Zymosterol

Zymosterol is a lipid of Sterol Lipids (ST) class. Zymosterol is associated with abnormalities such as Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease and Virus Diseases. The involved functions are known as Process, enzyme activity, Anabolism, Transcription, Genetic and Synthesis. Zymosterol often locates in Cytosol, Mitochondria, Articular system, Protoplasm and Tissue membrane. The associated genes with Zymosterol are Genome, Homologous Gene, Amino Acids, Acidic, Peptide Fragments and DLC1 gene. The related lipids are zymosterol, Cardiolipins, 25-azacholesterol, Sterols and Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Zymosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Zymosterol?

Zymosterol is suspected in Leishmaniasis, Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Zymosterol

MeSH term MeSH ID Detail
Limb Deformities, Congenital D017880 4 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Zymosterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Zymosterol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Zymosterol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Zymosterol?

Related references are published most in these journals:

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What genes are associated with Zymosterol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Zymosterol?

Knock-out

Knock-out are used in the study 'Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major.' (Chavali AK et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Zymosterol

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Authors Title Published Journal PubMed Link
Shin GH et al. Overexpression of genes of the fatty acid biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. 2012 Yeast pmid:22926964
Javitt NB Oxysteroids: a new class of steroids with autocrine and paracrine functions. 2004 Trends Endocrinol. Metab. pmid:15380811
Alvarez-Vasquez F et al. Mathematical modeling and validation of the ergosterol pathway in Saccharomyces cerevisiae. 2011 PLoS ONE pmid:22194828
Hameed S et al. Calcineurin signaling and membrane lipid homeostasis regulates iron mediated multidrug resistance mechanisms in Candida albicans. 2011 PLoS ONE pmid:21533276
Lange Y et al. Activation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cells. 2012 PLoS ONE pmid:22276143
Gleason JE et al. Analysis of hypoxia and hypoxia-like states through metabolite profiling. 2011 PLoS ONE pmid:21931840
Alvarez-Rueda N et al. Amino acid substitutions at the major insertion loop of Candida albicans sterol 14alpha-demethylase are involved in fluconazole resistance. 2011 PLoS ONE pmid:21698128
Cheng D et al. Lipid pathway alterations in Parkinson's disease primary visual cortex. 2011 PLoS ONE pmid:21387008
Leszczynska A et al. Investigating the effects of statins on cellular lipid metabolism using a yeast expression system. 2009 PLoS ONE pmid:20041128
Singh A and Prasad R Comparative lipidomics of azole sensitive and resistant clinical isolates of Candida albicans reveals unexpected diversity in molecular lipid imprints. 2011 PLoS ONE pmid:21559392