Zymosterol

Zymosterol is a lipid of Sterol Lipids (ST) class. Zymosterol is associated with abnormalities such as Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease and Virus Diseases. The involved functions are known as Process, enzyme activity, Anabolism, Transcription, Genetic and Synthesis. Zymosterol often locates in Cytosol, Mitochondria, Articular system, Protoplasm and Tissue membrane. The associated genes with Zymosterol are Genome, Homologous Gene, Amino Acids, Acidic, Peptide Fragments and DLC1 gene. The related lipids are zymosterol, Cardiolipins, 25-azacholesterol, Sterols and Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Zymosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Zymosterol?

Zymosterol is suspected in Leishmaniasis, Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Zymosterol

MeSH term MeSH ID Detail
Limb Deformities, Congenital D017880 4 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Zymosterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Zymosterol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Zymosterol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Zymosterol?

Related references are published most in these journals:

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What genes are associated with Zymosterol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Zymosterol?

Knock-out

Knock-out are used in the study 'Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major.' (Chavali AK et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Zymosterol

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Authors Title Published Journal PubMed Link
pmid:
Soustre I et al. Sterol metabolism and ERG2 gene regulation in the yeast Saccharomyces cerevisiae. 2000 FEBS Lett. pmid:10734216
Baudry K et al. The effect of the erg26-1 mutation on the regulation of lipid metabolism in Saccharomyces cerevisiae. 2001 J. Biol. Chem. pmid:11279045
Swain E et al. Sterol-dependent regulation of sphingolipid metabolism in Saccharomyces cerevisiae. 2002 J. Biol. Chem. pmid:12006573
Kaneshiro ES et al. The Pneumocystis carinii drug target S-adenosyl-L-methionine:sterol C-24 methyl transferase has a unique substrate preference. 2002 Mol. Microbiol. pmid:12010494
Nes WD et al. Purification, characterization and catalytic properties of human sterol 8-isomerase. 2002 Biochem. J. pmid:12133002
Chevy F et al. Limb malformations of rat fetuses exposed to a distal inhibitor of cholesterol biosynthesis. 2002 J. Lipid Res. pmid:12177163
Nes WD et al. Active site mapping and substrate channeling in the sterol methyltransferase pathway. 2002 J. Biol. Chem. pmid:12196515
Berthois Y et al. SR31747A is a sigma receptor ligand exhibiting antitumoural activity both in vitro and in vivo. 2003 Br. J. Cancer pmid:12569389
Lusa S et al. Differential mobilization of newly synthesized cholesterol and biosynthetic sterol precursors from cells. 2003 J. Biol. Chem. pmid:12657643