| MeSH term | MeSH ID | Detail |
|---|---|---|
| Limb Deformities, Congenital | D017880 | 4 associated lipids |
Total
1
Zymosterol
Zymosterol is a lipid of Sterol Lipids (ST) class. Zymosterol is associated with abnormalities such as Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease and Virus Diseases. The involved functions are known as Process, enzyme activity, Anabolism, Transcription, Genetic and Synthesis. Zymosterol often locates in Cytosol, Mitochondria, Articular system, Protoplasm and Tissue membrane. The associated genes with Zymosterol are Genome, Homologous Gene, Amino Acids, Acidic, Peptide Fragments and DLC1 gene. The related lipids are zymosterol, Cardiolipins, 25-azacholesterol, Sterols and Steroids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Zymosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Zymosterol?
Zymosterol is suspected in Leishmaniasis, Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Zymosterol
PubChem Associated disorders and diseases
What pathways are associated with Zymosterol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Zymosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Zymosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Zymosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Zymosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Zymosterol?
Knock-out
Knock-out are used in the study 'Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major.' (Chavali AK et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Zymosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Huijmans JG et al. | Effects of 22S-hydroxy-cholesterol and other hydroxylated sterols on the ACTH-stimulated steroid production in rat adrenal cells. | 1981 | Acta Endocrinol. | pmid:6263029 |
| Qi Y et al. | Med15B Regulates Acid Stress Response and Tolerance in Candida glabrata by Altering Membrane Lipid Composition. | 2017 | Appl. Environ. Microbiol. | pmid:28710262 |
| Nes WD et al. | Yeast sterol C24-methyltransferase: role of highly conserved tyrosine-81 in catalytic competence studied by site-directed mutagenesis and thermodynamic analysis. | 2008 | Arch. Biochem. Biophys. | pmid:18555004 |
| Nes WD et al. | Substrate-based inhibitors of the (S)-adenosyl-L-methionine:delta24(25)- to delta24(28)-sterol methyl transferase from Saccharomyces cerevisiae. | 1997 | Arch. Biochem. Biophys. | pmid:9185615 |
| Zhou W and Nes WD | Sterol methyltransferase2: purification, properties, and inhibition. | 2003 | Arch. Biochem. Biophys. | pmid:14622971 |
| Ganapathy K et al. | Purification, characterization and inhibition of sterol C24-methyltransferase from Candida albicans. | 2011 | Arch. Biochem. Biophys. | pmid:20946868 |
| Nes WD et al. | Sterol 24-C-methyltransferase: an enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans. | 2009 | Arch. Biochem. Biophys. | pmid:19014901 |
| Pikuleva I and Javitt NB | Novel sterols synthesized via the CYP27A1 metabolic pathway. | 2003 | Arch. Biochem. Biophys. | pmid:14622972 |
| ALEXANDER GJ and SCHWENK E | Studies on biosynthesis of cholesterol. IX. Zymosterol as a precursor of cholesterol. | 1957 | Arch. Biochem. Biophys. | pmid:13403684 |
| Nes WD et al. | Purification, characterization and catalytic properties of human sterol 8-isomerase. | 2002 | Biochem. J. | pmid:12133002 |
| Liu J et al. | Effect of substrate features and mutagenesis of active site tyrosine residues on the reaction course catalysed by Trypanosoma brucei sterol C-24-methyltransferase. | 2011 | Biochem. J. | pmid:21736559 |
| HÄ…c-Wydro K et al. | The influence of cholesterol precursor--desmosterol--on artificial lipid membranes. | 2015 | Biochim. Biophys. Acta | pmid:25960185 |
| Mo C et al. | The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). | 2004 | Biochim. Biophys. Acta | pmid:15522820 |
| Acuna-Johnson AP et al. | Stereochemistry of yeast delta 24-sterol methyl transferase. | 1997 | Bioorg. Med. Chem. | pmid:9208094 |
| Duarte NC et al. | Integrated analysis of metabolic phenotypes in Saccharomyces cerevisiae. | 2004 | BMC Genomics | pmid:15355549 |
| Rintala E et al. | Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae. | 2009 | BMC Genomics | pmid:19804647 |
| Ishida K et al. | Growth inhibition and ultrastructural alterations induced by Delta24(25)-sterol methyltransferase inhibitors in Candida spp. isolates, including non-albicans organisms. | 2009 | BMC Microbiol. | pmid:19379501 |
| Vargas FA et al. | Expanding a dynamic flux balance model of yeast fermentation to genome-scale. | 2011 | BMC Syst Biol | pmid:21595919 |
| Cimini D et al. | Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3. | 2009 | BMC Syst Biol | pmid:19200357 |