|
|
|
|
pmid:
|
Soustre I et al. |
Sterol metabolism and ERG2 gene regulation in the yeast Saccharomyces cerevisiae. |
2000 |
FEBS Lett. |
pmid:10734216
|
Baudry K et al. |
The effect of the erg26-1 mutation on the regulation of lipid metabolism in Saccharomyces cerevisiae. |
2001 |
J. Biol. Chem. |
pmid:11279045
|
Swain E et al. |
Sterol-dependent regulation of sphingolipid metabolism in Saccharomyces cerevisiae. |
2002 |
J. Biol. Chem. |
pmid:12006573
|
Kaneshiro ES et al. |
The Pneumocystis carinii drug target S-adenosyl-L-methionine:sterol C-24 methyl transferase has a unique substrate preference. |
2002 |
Mol. Microbiol. |
pmid:12010494
|
Nes WD et al. |
Purification, characterization and catalytic properties of human sterol 8-isomerase. |
2002 |
Biochem. J. |
pmid:12133002
|
Chevy F et al. |
Limb malformations of rat fetuses exposed to a distal inhibitor of cholesterol biosynthesis. |
2002 |
J. Lipid Res. |
pmid:12177163
|
Nes WD et al. |
Active site mapping and substrate channeling in the sterol methyltransferase pathway. |
2002 |
J. Biol. Chem. |
pmid:12196515
|
Berthois Y et al. |
SR31747A is a sigma receptor ligand exhibiting antitumoural activity both in vitro and in vivo. |
2003 |
Br. J. Cancer |
pmid:12569389
|
Lusa S et al. |
Differential mobilization of newly synthesized cholesterol and biosynthetic sterol precursors from cells. |
2003 |
J. Biol. Chem. |
pmid:12657643
|
Marijanovic Z et al. |
Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis. |
2003 |
Mol. Endocrinol. |
pmid:12829805
|
ALEXANDER GJ and SCHWENK E |
Studies on biosynthesis of cholesterol. IX. Zymosterol as a precursor of cholesterol. |
1957 |
Arch. Biochem. Biophys. |
pmid:13403684
|
SCHROEPFER GJ |
Conversion of zymosterol-C-14 and zymostenol-H3 to cholesterol by rat liver homogenates and intact rats. |
1961 |
J. Biol. Chem. |
pmid:13748688
|
Veen M et al. |
Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. |
2003 |
FEMS Yeast Res. |
pmid:14554200
|
Zhou W and Nes WD |
Sterol methyltransferase2: purification, properties, and inhibition. |
2003 |
Arch. Biochem. Biophys. |
pmid:14622971
|
Pikuleva I and Javitt NB |
Novel sterols synthesized via the CYP27A1 metabolic pathway. |
2003 |
Arch. Biochem. Biophys. |
pmid:14622972
|
Duarte NC et al. |
Integrated analysis of metabolic phenotypes in Saccharomyces cerevisiae. |
2004 |
BMC Genomics |
pmid:15355549
|
Javitt NB |
Oxysteroids: a new class of steroids with autocrine and paracrine functions. |
2004 |
Trends Endocrinol. Metab. |
pmid:15380811
|
Suárez Y et al. |
Synergistic upregulation of low-density lipoprotein receptor activity by tamoxifen and lovastatin. |
2004 |
Cardiovasc. Res. |
pmid:15485695
|
Mo C et al. |
The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). |
2004 |
Biochim. Biophys. Acta |
pmid:15522820
|
Müllner H et al. |
YEH2/YLR020c encodes a novel steryl ester hydrolase of the yeast Saccharomyces cerevisiae. |
2005 |
J. Biol. Chem. |
pmid:15632184
|
Kanagasabai R et al. |
Disruption of ergosterol biosynthesis, growth, and the morphological transition in Candida albicans by sterol methyltransferase inhibitors containing sulfur at C-25 in the sterol side chain. |
2004 |
Lipids |
pmid:15638241
|
Kaneshiro ES |
Sterol metabolism in the opportunistic pathogen Pneumocystis: advances and new insights. |
2004 |
Lipids |
pmid:15638243
|
Liu Y et al. |
Cytochrome P450 17alpha hydroxylase/17,20 lyase (CYP17) function in cholesterol biosynthesis: identification of squalene monooxygenase (epoxidase) activity associated with CYP17 in Leydig cells. |
2005 |
Mol. Endocrinol. |
pmid:15761033
|
Liu H et al. |
Cloning and characterization of human form 2 type 7 17beta-hydroxysteroid dehydrogenase, a primarily 3beta-keto reductase and estrogen activating and androgen inactivating enzyme. |
2005 |
J. Steroid Biochem. Mol. Biol. |
pmid:15862963
|
Germann M et al. |
Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis. |
2005 |
J. Biol. Chem. |
pmid:16120615
|
Almaas E et al. |
The activity reaction core and plasticity of metabolic networks. |
2005 |
PLoS Comput. Biol. |
pmid:16362071
|
Zhou W et al. |
Mechanistic analysis of a multiple product sterol methyltransferase implicated in ergosterol biosynthesis in Trypanosoma brucei. |
2006 |
J. Biol. Chem. |
pmid:16414960
|
Chemler JA et al. |
Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae. |
2006 |
Microb. Cell Fact. |
pmid:16719921
|
Megha O et al. |
Cholesterol precursors stabilize ordinary and ceramide-rich ordered lipid domains (lipid rafts) to different degrees. Implications for the Bloch hypothesis and sterol biosynthesis disorders. |
2006 |
J. Biol. Chem. |
pmid:16735517
|
Yang C et al. |
Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands. |
2006 |
J. Biol. Chem. |
pmid:16857673
|
Steffensen KR et al. |
Reduced fertility and inability of oocytes to resume meiosis in mice deficient of the Lxr genes. |
2006 |
Mol. Cell. Endocrinol. |
pmid:16895745
|
Cushion MT et al. |
Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite. |
2007 |
PLoS ONE |
pmid:17487271
|
Iwaki T et al. |
Multiple functions of ergosterol in the fission yeast Schizosaccharomyces pombe. |
2008 |
Microbiology (Reading, Engl.) |
pmid:18310029
|
Chavali AK et al. |
Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major. |
2008 |
Mol. Syst. Biol. |
pmid:18364711
|
Andersen MR et al. |
Metabolic model integration of the bibliome, genome, metabolome and reactome of Aspergillus niger. |
2008 |
Mol. Syst. Biol. |
pmid:18364712
|
Nes WD et al. |
Yeast sterol C24-methyltransferase: role of highly conserved tyrosine-81 in catalytic competence studied by site-directed mutagenesis and thermodynamic analysis. |
2008 |
Arch. Biochem. Biophys. |
pmid:18555004
|
Vinci G et al. |
Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses. |
2008 |
PLoS ONE |
pmid:18682733
|
Snitkin ES et al. |
Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions. |
2008 |
Genome Biol. |
pmid:18808699
|
Nes WD et al. |
Sterol 24-C-methyltransferase: an enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans. |
2009 |
Arch. Biochem. Biophys. |
pmid:19014901
|
Cimini D et al. |
Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3. |
2009 |
BMC Syst Biol |
pmid:19200357
|
Ishida K et al. |
Growth inhibition and ultrastructural alterations induced by Delta24(25)-sterol methyltransferase inhibitors in Candida spp. isolates, including non-albicans organisms. |
2009 |
BMC Microbiol. |
pmid:19379501
|
Lange Y et al. |
Movement of zymosterol, a precursor of cholesterol, among three membranes in human fibroblasts. |
1991 |
J. Biol. Chem. |
pmid:1939176
|
Kawashima H et al. |
Differences in sterol composition between male and female gonads of dominant limpet species. |
2009 |
Lipids |
pmid:19452182
|
Acimovic J et al. |
Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells. |
2009 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:19525158
|
de Souza W and Rodrigues JC |
Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. |
2009 |
Interdiscip Perspect Infect Dis |
pmid:19680554
|
Rintala E et al. |
Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae. |
2009 |
BMC Genomics |
pmid:19804647
|
Leszczynska A et al. |
Investigating the effects of statins on cellular lipid metabolism using a yeast expression system. |
2009 |
PLoS ONE |
pmid:20041128
|
Jokela H et al. |
Hydroxysteroid (17beta) dehydrogenase 7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos. |
2010 |
Endocrinology |
pmid:20185768
|
Fon Tacer K et al. |
Adaptation of cholesterol synthesis to fasting and TNF-alpha: profiling cholesterol intermediates in the liver, brain, and testis. |
2010 |
J. Steroid Biochem. Mol. Biol. |
pmid:20206258
|