MeSH term | MeSH ID | Detail |
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Limb Deformities, Congenital | D017880 | 4 associated lipids |
Zymosterol is a lipid of Sterol Lipids (ST) class. Zymosterol is associated with abnormalities such as Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease and Virus Diseases. The involved functions are known as Process, enzyme activity, Anabolism, Transcription, Genetic and Synthesis. Zymosterol often locates in Cytosol, Mitochondria, Articular system, Protoplasm and Tissue membrane. The associated genes with Zymosterol are Genome, Homologous Gene, Amino Acids, Acidic, Peptide Fragments and DLC1 gene. The related lipids are zymosterol, Cardiolipins, 25-azacholesterol, Sterols and Steroids. The related experimental models are Knock-out.
To understand associated biological information of Zymosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Zymosterol is suspected in Leishmaniasis, Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Zymosterol
MeSH term | MeSH ID | Detail |
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Limb Deformities, Congenital | D017880 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major.' (Chavali AK et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Nes WD et al. | Purification, characterization and catalytic properties of human sterol 8-isomerase. | 2002 | Biochem. J. | pmid:12133002 |
Liu J et al. | Effect of substrate features and mutagenesis of active site tyrosine residues on the reaction course catalysed by Trypanosoma brucei sterol C-24-methyltransferase. | 2011 | Biochem. J. | pmid:21736559 |
HÄ…c-Wydro K et al. | The influence of cholesterol precursor--desmosterol--on artificial lipid membranes. | 2015 | Biochim. Biophys. Acta | pmid:25960185 |
Mo C et al. | The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). | 2004 | Biochim. Biophys. Acta | pmid:15522820 |
Acuna-Johnson AP et al. | Stereochemistry of yeast delta 24-sterol methyl transferase. | 1997 | Bioorg. Med. Chem. | pmid:9208094 |
Duarte NC et al. | Integrated analysis of metabolic phenotypes in Saccharomyces cerevisiae. | 2004 | BMC Genomics | pmid:15355549 |
Rintala E et al. | Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae. | 2009 | BMC Genomics | pmid:19804647 |
Ishida K et al. | Growth inhibition and ultrastructural alterations induced by Delta24(25)-sterol methyltransferase inhibitors in Candida spp. isolates, including non-albicans organisms. | 2009 | BMC Microbiol. | pmid:19379501 |
Vargas FA et al. | Expanding a dynamic flux balance model of yeast fermentation to genome-scale. | 2011 | BMC Syst Biol | pmid:21595919 |
Cimini D et al. | Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3. | 2009 | BMC Syst Biol | pmid:19200357 |