| MeSH term | MeSH ID | Detail |
|---|---|---|
| Limb Deformities, Congenital | D017880 | 4 associated lipids |
Total
1
Zymosterol
Zymosterol is a lipid of Sterol Lipids (ST) class. Zymosterol is associated with abnormalities such as Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease and Virus Diseases. The involved functions are known as Process, enzyme activity, Anabolism, Transcription, Genetic and Synthesis. Zymosterol often locates in Cytosol, Mitochondria, Articular system, Protoplasm and Tissue membrane. The associated genes with Zymosterol are Genome, Homologous Gene, Amino Acids, Acidic, Peptide Fragments and DLC1 gene. The related lipids are zymosterol, Cardiolipins, 25-azacholesterol, Sterols and Steroids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Zymosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Zymosterol?
Zymosterol is suspected in Leishmaniasis, Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Zymosterol
PubChem Associated disorders and diseases
What pathways are associated with Zymosterol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Zymosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Zymosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Zymosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Zymosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Zymosterol?
Knock-out
Knock-out are used in the study 'Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major.' (Chavali AK et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Zymosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Marijanovic Z et al. | Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis. | 2003 | Mol. Endocrinol. | pmid:12829805 |
| ALEXANDER GJ and SCHWENK E | Studies on biosynthesis of cholesterol. IX. Zymosterol as a precursor of cholesterol. | 1957 | Arch. Biochem. Biophys. | pmid:13403684 |
| SCHROEPFER GJ | Conversion of zymosterol-C-14 and zymostenol-H3 to cholesterol by rat liver homogenates and intact rats. | 1961 | J. Biol. Chem. | pmid:13748688 |
| Veen M et al. | Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. | 2003 | FEMS Yeast Res. | pmid:14554200 |
| Zhou W and Nes WD | Sterol methyltransferase2: purification, properties, and inhibition. | 2003 | Arch. Biochem. Biophys. | pmid:14622971 |
| Pikuleva I and Javitt NB | Novel sterols synthesized via the CYP27A1 metabolic pathway. | 2003 | Arch. Biochem. Biophys. | pmid:14622972 |
| Duarte NC et al. | Integrated analysis of metabolic phenotypes in Saccharomyces cerevisiae. | 2004 | BMC Genomics | pmid:15355549 |
| Javitt NB | Oxysteroids: a new class of steroids with autocrine and paracrine functions. | 2004 | Trends Endocrinol. Metab. | pmid:15380811 |
| Suárez Y et al. | Synergistic upregulation of low-density lipoprotein receptor activity by tamoxifen and lovastatin. | 2004 | Cardiovasc. Res. | pmid:15485695 |
| Mo C et al. | The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). | 2004 | Biochim. Biophys. Acta | pmid:15522820 |