|
|
|
|
pmid:
|
CHAUDHURI AC et al. |
Biosynthesis of pregnenolone from 22-hydroxycholesterol. |
1962 |
J. Biol. Chem. |
pmid:13878470
|
Huijmans JG et al. |
Effects of 22S-hydroxy-cholesterol and other hydroxylated sterols on the ACTH-stimulated steroid production in rat adrenal cells. |
1981 |
Acta Endocrinol. |
pmid:6263029
|
Huijmans JG et al. |
Conversion of 22S-hydroxy-cholesterol and its effects on the metabolism of other sterols in rat adrenal cells and bovine adrenal mitochondria. |
1982 |
Acta Endocrinol. |
pmid:6289587
|
Sullivan MH and Cooke BA |
Stimulation of cholesterol side-chain cleavage by a luteinizing-hormone-releasing hormone (luliberin) agonist (ICI 118630) in rat Leydig cells. |
1983 |
Biochem. J. |
pmid:6230077
|
Bates SR et al. |
Prevention of the hyperlipidemic serum or LDL-induced cellular cholesterol ester accumulation by 22-hydroxycholesterol and its analogue. |
1983 |
Biochim. Biophys. Acta |
pmid:6615863
|
Huijmans JG et al. |
Effects of some hydroxylated sterols on the steroid production in isolated rat adrenal glomerulosa and fasciculata/reticularis cells in the presence of potassium, angiotensin II or ACTH. |
1984 |
Acta Endocrinol. |
pmid:6322498
|
Risbridger GP et al. |
The interaction of hCG, hydroxysteroids and interstitial fluid on rat Leydig cell steroidogenesis in vitro. |
1986 |
J. Reprod. Fertil. |
pmid:3723471
|
Carr BR and Mason JI |
The effects of alpha-human atrial natriuretic polypeptide on steroidogenesis by fetal zone cells of the human fetal adrenal gland. |
1988 |
Am. J. Obstet. Gynecol. |
pmid:2849878
|
Cupp JR and Vickery LE |
Adrenodoxin with a COOH-terminal deletion (des 116-128) exhibits enhanced activity. |
1989 |
J. Biol. Chem. |
pmid:2912975
|
Meikle AW et al. |
Nonesterified fatty acids modulate steroidogenesis in mouse Leydig cells. |
1989 |
Am. J. Physiol. |
pmid:2558577
|
Guo H et al. |
Interleukin-2 is a potent inhibitor of Leydig cell steroidogenesis. |
1990 |
Endocrinology |
pmid:2167211
|
Hedger MP and Eddy EM |
Leydig cell cooperation in vitro: evidence for communication between adult rat Leydig cells. |
1990 Jan-Feb |
J. Androl. |
pmid:2155894
|
Mauduit C et al. |
Tumor necrosis factor alpha inhibits gonadotropin action in cultured porcine Leydig cells: site(s) of action. |
1991 |
Endocrinology |
pmid:1659519
|
Meikle AW et al. |
Extracellular calcium and luteinizing hormone effects on 22-hydroxycholesterol used for testosterone production in mouse Leydig cells. |
1991 Mar-Apr |
J. Androl. |
pmid:2050582
|
Gocze PM and Freeman DA |
A cholesteryl ester hydrolase inhibitor blocks cholesterol translocation into the mitochondria of MA-10 Leydig tumor cells. |
1992 |
Endocrinology |
pmid:1332853
|
Fitz TA et al. |
Effects of substrate supplementation with hydroxycholesterol analogues and serum lipoproteins on ovine luteal cell progesterone secretion in vitro: demonstration of prostaglandin F2 alpha luteolytic actions in a defined model system. |
1993 |
J. Reprod. Fertil. |
pmid:8464026
|
Abayasekara DR et al. |
Mode of action of prostaglandin F2 alpha in human luteinized granulosa cells: role of protein kinase C. |
1993 |
Mol. Cell. Endocrinol. |
pmid:8143907
|
Abayasekara RE and Flint AP |
A novel phospholipase C inhibitor U73122, inhibits phospholipase C-independent processes in rat luteal cells. |
1993 |
Biochem. Soc. Trans. |
pmid:8131934
|
Stocco DM et al. |
The effects of hydrogen peroxide on steroidogenesis in mouse Leydig tumor cells. |
1993 |
Endocrinology |
pmid:8243310
|
Sourdaine P and Garnier DH |
Stage-dependent modulation of Sertoli cell steroid production in dogfish (Scyliorhinus canicula). |
1993 |
J. Reprod. Fertil. |
pmid:8385221
|
Freeman DA et al. |
Finasteride blocks progesterone synthesis in MA-10 Leydig tumor cells. |
1993 |
Endocrinology |
pmid:8404636
|
Boujrad N et al. |
Inhibition of hormone-stimulated steroidogenesis in cultured Leydig tumor cells by a cholesterol-linked phosphorothioate oligodeoxynucleotide antisense to diazepam-binding inhibitor. |
1993 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:8390677
|
Musicki B et al. |
Inhibition of protein synthesis and hormone-sensitive steroidogenesis in response to hydrogen peroxide in rat luteal cells. |
1994 |
Endocrinology |
pmid:7507829
|
Khanna A et al. |
Heat shock protein induction blocks hormone-sensitive steroidogenesis in rat luteal cells. |
1994 |
Steroids |
pmid:8140601
|
Picard-Hagen N et al. |
Glucocorticoids enhance the cholesterol side-chain cleavage activity of ovine adrenocortical mitochondria. |
1995 |
J. Steroid Biochem. Mol. Biol. |
pmid:7577721
|
Brannian JD et al. |
Hydrogen peroxide suppresses low-density lipoprotein (LDL) uptake and LDL-supported steroidogenesis by porcine luteal cells. |
1995 |
Mol. Cell. Endocrinol. |
pmid:7556884
|
Verhagen JC et al. |
Physical effects of biologically formed cholesterol oxidation products on lipid membranes investigated with fluorescence depolarization spectroscopy and electron spin resonance. |
1996 |
J. Lipid Res. |
pmid:8827521
|
Mele PG et al. |
Site of action of proteinases in the activation of steroidogenesis in rat adrenal gland. |
1996 |
Biochim. Biophys. Acta |
pmid:8599603
|
Sugano S et al. |
Identification of intermediates in the conversion of cholesterol to pregnenolone with a reconstituted cytochrome p-450scc system: accumulation of the intermediate modulated by the adrenodoxin level. |
1996 |
J. Biochem. |
pmid:8947841
|
Doris PA et al. |
Ouabain production by cultured adrenal cells. |
1996 |
Endocrinology |
pmid:8593799
|
Pezzi V et al. |
Role of calmodulin-dependent protein kinase II in the acute stimulation of aldosterone production. |
1996 |
J. Steroid Biochem. Mol. Biol. |
pmid:8903426
|
Janowski BA et al. |
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. |
1996 |
Nature |
pmid:8878485
|
Hawi SR et al. |
Raman microspectroscopy of intracellular cholesterol crystals in cultured bovine coronary artery endothelial cells. |
1997 |
J. Lipid Res. |
pmid:9300781
|
Lehmann JM et al. |
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. |
1997 |
J. Biol. Chem. |
pmid:9013544
|
Lala DS et al. |
Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols. |
1997 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:9144161
|
Marinero MJ et al. |
Specific effect of arachidonic acid on 17beta-hydroxysteroid dehydrogenase in rat Leydig cells. |
1998 |
FEBS Lett. |
pmid:9475159
|
Huang CJ et al. |
Synergistic activation of RLD-1 by agents triggering PKA and PKC dependent signalling. |
1998 |
Biochem. Biophys. Res. Commun. |
pmid:9500983
|
Lin T et al. |
Interferon-gamma inhibits the steroidogenic acute regulatory protein messenger ribonucleic acid expression and protein levels in primary cultures of rat Leydig cells. |
1998 |
Endocrinology |
pmid:9564825
|
Lin T et al. |
Interleukin-1 inhibits Leydig cell steroidogenesis without affecting steroidogenic acute regulatory protein messenger ribonucleic acid or protein levels. |
1998 |
J. Endocrinol. |
pmid:9582502
|
Bosc MJ and Nicolle A |
Androstenedione and progesterone production in vitro by the inner or the outer theca cells in preovulatory follicles of gonadotropin stimulated calves. |
1998 |
Anim. Reprod. Sci. |
pmid:9672665
|
Dirami G and Cooke BA |
Effect of a dopamine agonist on luteinizing hormone receptors, cyclic AMP production and steroidogenesis in rat Leydig cells. |
1998 |
Toxicol. Appl. Pharmacol. |
pmid:9653071
|
Cymeryng CB et al. |
Effects of L-arginine in rat adrenal cells: involvement of nitric oxide synthase. |
1999 |
Endocrinology |
pmid:10385387
|
Hanley K et al. |
Fetal epidermal differentiation and barrier development In vivo is accelerated by nuclear hormone receptor activators. |
1999 |
J. Invest. Dermatol. |
pmid:10571735
|
Ogilvie KM et al. |
The inhibitory effect of intracerebroventricularly injected interleukin 1beta on testosterone secretion in the rat: role of steroidogenic acute regulatory protein. |
1999 |
Biol. Reprod. |
pmid:9916024
|
Wiebel FF et al. |
Ligand-independent coregulator recruitment by the triply activatable OR1/retinoid X receptor-alpha nuclear receptor heterodimer. |
1999 |
Mol. Endocrinol. |
pmid:10406462
|
Stocco CO and Deis RP |
Luteinizing hormone inhibits conversion of pregnenolone to progesterone in luteal cells from rats on day 19 of pregnancy. |
1999 |
Biol. Reprod. |
pmid:10026123
|
Hanley K et al. |
Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription. |
2000 |
J. Invest. Dermatol. |
pmid:10692116
|
Costet P et al. |
Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. |
2000 |
J. Biol. Chem. |
pmid:10858438
|
Murono EP et al. |
Octylphenol inhibits testosterone biosynthesis by cultured precursor and immature Leydig cells from rat testes. |
2000 May-Jun |
Reprod. Toxicol. |
pmid:10838129
|
Mauduit C et al. |
Leukemia inhibitory factor antagonizes gonadotropin induced-testosterone synthesis in cultured porcine leydig cells: sites of action. |
2001 |
Endocrinology |
pmid:11356700
|
Yoshikawa T et al. |
Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter. |
2001 |
Mol. Cell. Biol. |
pmid:11287605
|
Laffitte BA et al. |
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11149950
|
DeBose-Boyd RA et al. |
Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:11171976
|
Spencer TA et al. |
Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha. |
2001 |
J. Med. Chem. |
pmid:11300870
|
Chiang JY et al. |
Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha). |
2001 |
Gene |
pmid:11179691
|
Liu MY et al. |
The inhibitory effects of lead on steroidogenesis in MA-10 mouse Leydig tumor cells. |
2001 |
Life Sci. |
pmid:11213355
|
Lorkowski S et al. |
Genomic sequence and structure of the human ABCG1 (ABC8) gene. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11162488
|
Tu AY and Albers JJ |
Functional analysis of the transcriptional activity of the mouse phospholipid transfer protein gene. |
2001 |
Biochem. Biophys. Res. Commun. |
pmid:11573953
|
Huang MC and Miller WL |
Creation and activity of COS-1 cells stably expressing the F2 fusion of the human cholesterol side-chain cleavage enzyme system. |
2001 |
Endocrinology |
pmid:11356706
|
Wu CS et al. |
Melatonin inhibits the expression of steroidogenic acute regulatory protein and steroidogenesis in MA-10 cells. |
2001 Mar-Apr |
J. Androl. |
pmid:11229798
|
Malerød L et al. |
Oxysterol-activated LXRalpha/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:12470667
|
Yao ZX et al. |
22R-Hydroxycholesterol protects neuronal cells from beta-amyloid-induced cytotoxicity by binding to beta-amyloid peptide. |
2002 |
J. Neurochem. |
pmid:12437582
|
Goldman JM and Murr AS |
Alterations in ovarian follicular progesterone secretion by elevated exposures to the drinking water disinfection by-product dibromoacetic acid: examination of the potential site(s) of impact along the steroidogenic pathway. |
2002 |
Toxicology |
pmid:11836015
|
Kömüves LG et al. |
Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis. |
2002 |
J. Invest. Dermatol. |
pmid:11851872
|
Nishida Y et al. |
Expression and functional analyses of novel mutations of ATP-binding cassette transporter-1 in Japanese patients with high-density lipoprotein deficiency. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:11785958
|
Reddy ST et al. |
ATP-binding cassette transporter 1 participates in LDL oxidation by artery wall cells. |
2002 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:12426219
|
Stein O et al. |
Macrophage cholesterol efflux to free apoprotein A-I in C3H and C57BL/6 mice. |
2002 |
Biochem. Biophys. Res. Commun. |
pmid:11820773
|
Wellington CL et al. |
Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol. |
2002 |
J. Lipid Res. |
pmid:12401893
|
Ragoobir J et al. |
Stimulation of progesterone production in human granulosa-lutein cells by lipoproteins: evidence for cholesterol-independent actions of high-density lipoproteins. |
2002 |
J. Endocrinol. |
pmid:11927389
|
Cheng J et al. |
The inhibitory effects of manganese on steroidogenesis in rat primary Leydig cells by disrupting steroidogenic acute regulatory (StAR) protein expression. |
2003 |
Toxicology |
pmid:12699903
|
Hsu CC et al. |
Regulatory mechanism of Cordyceps sinensis mycelium on mouse Leydig cell steroidogenesis. |
2003 |
FEBS Lett. |
pmid:12753921
|
Bortnick AE et al. |
Identification and characterization of rodent ABCA1 in isolated type II pneumocytes. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
pmid:12909583
|
Ide T et al. |
Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling. |
2003 |
Mol. Endocrinol. |
pmid:12730332
|
Koldamova RP et al. |
22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion. |
2003 |
J. Biol. Chem. |
pmid:12547833
|
Nguyen DH and Taub DD |
Membrane incorporation of 22-hydroxycholesterol inhibits chemokine receptor activity. |
2003 |
Exp. Cell Res. |
pmid:12706121
|
Fowler AJ et al. |
Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production. |
2003 |
J. Invest. Dermatol. |
pmid:12542530
|
Xia H and Redman CM |
Oxysterols suppress constitutive fibrinogen expression. |
2003 |
Thromb. Haemost. |
pmid:12876624
|
Antonio V et al. |
Oxysterol and 9-cis-retinoic acid stimulate the group IIA secretory phospholipase A2 gene in rat smooth-muscle cells. |
2003 |
Biochem. J. |
pmid:12882648
|
Goodwin B et al. |
Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha. |
2003 |
Mol. Endocrinol. |
pmid:12554795
|
Kaneko E et al. |
Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist. |
2003 |
J. Biol. Chem. |
pmid:12847102
|
Nazarov PA et al. |
Formation and functioning of fused cholesterol side-chain cleavage enzymes. |
2003 |
DNA Cell Biol. |
pmid:12823901
|
Thiboutot D et al. |
Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte cell line (SEB-1). |
2003 |
J. Invest. Dermatol. |
pmid:12787114
|
Sriraman V and Jagannadha Rao A |
Evaluation of the role of FSH in regulation of Leydig cell function during different stages of its differentiation. |
2004 |
Mol. Cell. Endocrinol. |
pmid:15353182
|
Huuskonen J et al. |
Role of p160 coactivator complex in the activation of liver X receptor. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:14764426
|
Lecanu L et al. |
Identification of naturally occurring spirostenols preventing beta-amyloid-induced neurotoxicity. |
2004 |
Steroids |
pmid:14715372
|
Dubuc G et al. |
Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:15178557
|
Yoon JH et al. |
Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis. |
2004 |
Hepatology |
pmid:14999691
|
Llaverias G et al. |
Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism. |
2004 |
J. Lipid Res. |
pmid:15314095
|
Suzuki S et al. |
Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism. |
2004 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:14726413
|
Denis M et al. |
Molecular and cellular physiology of apolipoprotein A-I lipidation by the ATP-binding cassette transporter A1 (ABCA1). |
2004 |
J. Biol. Chem. |
pmid:14660648
|
Schmuth M et al. |
The effect of LXR activators on AP-1 proteins in keratinocytes. |
2004 |
J. Invest. Dermatol. |
pmid:15191540
|
Haidar B et al. |
Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter. |
2004 |
J. Biol. Chem. |
pmid:14701824
|
O'Connell BJ et al. |
Cellular physiology of cholesterol efflux in vascular endothelial cells. |
2004 |
Circulation |
pmid:15492319
|
Tang CK et al. |
Oxidized LDL upregulated ATP binding cassette transporter-1 in THP-1 macrophages. |
2004 |
Acta Pharmacol. Sin. |
pmid:15132822
|
Weedon-Fekjaer MS et al. |
Liver X receptors mediate inhibition of hCG secretion in a human placental trophoblast cell line. |
2005 |
Placenta |
pmid:16226121
|
Shouhed D et al. |
Osteogenic oxysterols inhibit the adverse effects of oxidative stress on osteogenic differentiation of marrow stromal cells. |
2005 |
J. Cell. Biochem. |
pmid:15880703
|
Norata GD et al. |
Liver X receptor and retinoic X receptor agonists modulate the expression of genes involved in lipid metabolism in human endothelial cells. |
2005 |
Int. J. Mol. Med. |
pmid:16142410
|
Yasuda T et al. |
Suppression of inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 22(R)-hydroxycholesterol requires de novo protein synthesis in activated macrophages. |
2005 |
J. Steroid Biochem. Mol. Biol. |
pmid:16146692
|
Matsuzaki J et al. |
Immunosteroid as a regulator for Th1/Th2 balance: its possible role in autoimmune diseases. |
2005 |
Autoimmunity |
pmid:16227152
|