| MeSH term | MeSH ID | Detail |
|---|---|---|
| Fatty Liver | D005234 | 48 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Coronary Artery Disease | D003324 | 47 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Smith-Lemli-Opitz Syndrome | D019082 | 7 associated lipids |
Lathosterol
Lathosterol is a lipid of Sterol Lipids (ST) class. Lathosterol is associated with abnormalities such as Obesity, Diabetes, Metabolic syndrome, Cholestasis and Hypertensive disease. The involved functions are known as Increased Cholesterol Synthesis, Mutation, Synthesis, cholesterol metabolism and Insulin Resistance. Lathosterol often locates in Visceral Fat, Blood, Body tissue, Membrane and Hepatic. The associated genes with Lathosterol are apolipoprotein E-3, Alleles, ABCG8 gene, CYP7A1 gene and STN gene. The related lipids are Sterols, lathosterol, Total cholesterol, campesterol and Cholestanes. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Lathosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Lathosterol?
Lathosterol is suspected in Obesity, Diabetes, Asthma, Cardiovascular Diseases, Diabetes Mellitus, Non-Insulin-Dependent, Cholestasis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lathosterol
PubChem Associated disorders and diseases
What pathways are associated with Lathosterol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Lathosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Lathosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Lathosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Lathosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Lathosterol?
Knock-out
Knock-out are used in the study 'C-5(6) sterol desaturase from tetrahymena thermophila: Gene identification and knockout, sequence analysis, and comparison to other C-5(6) sterol desaturases.' (Nusblat AD et al., 2009).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Lathosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Weingärtner O et al. | Plant sterol ester diet supplementation increases serum plant sterols and markers of cholesterol synthesis, but has no effect on total cholesterol levels. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:27473562 |
| Sawamura A et al. | Cholesterol metabolism as a prognostic marker in patients with mildly symptomatic nonischemic dilated cardiomyopathy. | 2017 | J Cardiol | pmid:27686044 |
| Makarova AM et al. | Attenuation of UVR-induced vitamin D synthesis in a mouse model deleted for keratinocyte lathosterol 5-desaturase. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:28330720 |
| Othman RA et al. | Thyroid Hormone Status in Sitosterolemia Is Modified by Ezetimibe. | 2017 | J. Pediatr. | pmid:28625503 |
| Stellaard F et al. | The value of surrogate markers to monitor cholesterol absorption, synthesis and bioconversion to bile acids under lipid lowering therapies. | 2017 | J. Steroid Biochem. Mol. Biol. | pmid:27060336 |
| Matos Cordeiro Borges M et al. | Molecularly imprinted solid-phase extraction coupled with LC-APCI-MS-MS for the selective determination of serum cholesterol. | 2017 | Electrophoresis | pmid:28543542 |
| Mignarri A et al. | Evaluation of cholesterol metabolism in cerebrotendinous xanthomatosis. | 2016 | J. Inherit. Metab. Dis. | pmid:26153518 |
| Andrade I et al. | Cholesterol absorption and synthesis markers in Portuguese hypercholesterolemic adults: A cross-sectional study. | 2016 | Eur. J. Intern. Med. | pmid:26577223 |
| Herzog E et al. | Reconstituted high-density lipoprotein can elevate plasma alanine aminotransferase by transient depletion of hepatic cholesterol: role of the phospholipid component. | 2016 | J Appl Toxicol | pmid:26651060 |
| Tsujita K et al. | Synergistic effect of ezetimibe addition on coronary atheroma regression in patients with prior statin therapy: Subanalysis of PRECISE-IVUS trial. | 2016 | Eur J Prev Cardiol | pmid:27296705 |