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Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation. |
2012 |
BMC Complement Altern Med |
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The triterpenoid cucurbitacin B augments the antiproliferative activity of chemotherapy in human breast cancer. |
2013 |
Int. J. Cancer |
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Cucurbitacin B potently suppresses non-small-cell lung cancer growth: identification of intracellular thiols as critical targets. |
2013 |
Cancer Lett. |
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The effectiveness of cucurbitacin B in BRCA1 defective breast cancer cells. |
2013 |
PLoS ONE |
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Duportets L et al. |
Steroid hormone signaling is involved in the age-dependent behavioral response to sex pheromone in the adult male moth Agrotis ipsilon. |
2013 |
Gen. Comp. Endocrinol. |
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Nanobiotechnology can boost crop production and quality: first evidence from increased plant biomass, fruit yield and phytomedicine content in bitter melon (Momordica charantia). |
2013 |
BMC Biotechnol. |
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Jianbo G et al. |
The anti-melanoma efficiency of the intratumoral injection of cucurbitacin-loaded sustained-release carriers: a PLGA particle system. |
2013 |
J Pharm Sci |
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Cucurbitacin B and cucurbitacin I suppress adipocyte differentiation through inhibition of STAT3 signaling. |
2014 |
Food Chem. Toxicol. |
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Ma J et al. |
Cucurbitacin B inhibits the translational expression of hypoxia-inducible factor-1α. |
2014 |
Eur. J. Pharmacol. |
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Guo J et al. |
Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner. |
2014 |
PLoS ONE |
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Lv Q et al. |
Application of spray granulation for conversion of mixed phospholipid-bile salt micelles to dry powder form: influence of drug hydrophobicity on nanoparticle reagglomeration. |
2014 |
Int J Nanomedicine |
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Gao Y et al. |
Inactivation of ATP citrate lyase by Cucurbitacin B: A bioactive compound from cucumber, inhibits prostate cancer growth. |
2014 |
Cancer Lett. |
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Zhang YT et al. |
VASP activation via the Gα13/RhoA/PKA pathway mediates cucurbitacin-B-induced actin aggregation and cofilin-actin rod formation. |
2014 |
PLoS ONE |
pmid:24691407
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Gupta P and Srivastava SK |
Inhibition of Integrin-HER2 signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression. |
2014 |
Oncotarget |
pmid:24729020
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Husen A and Siddiqi KS |
Carbon and fullerene nanomaterials in plant system. |
2014 |
J Nanobiotechnology |
pmid:24766786
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Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells. |
2014 |
Mol Med Rep |
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Yu C et al. |
[Preparation and characterization of cucurbitacin B sodium deoxycholate/phospholipid-mixed oral fast dissolving film and antitumor activity study]. |
2014 |
Zhongguo Zhong Yao Za Zhi |
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Shang Y et al. |
Cucurbitacin-B inhibits neuroblastoma cell proliferation through up-regulation of PTEN. |
2014 |
Eur Rev Med Pharmacol Sci |
pmid:25487942
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Silva IT et al. |
In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B. |
2015 |
PLoS ONE |
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Shukla S et al. |
Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis. |
2015 |
Cancer Prev Res (Phila) |
pmid:25813524
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pmid:25882012
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pmid:26018422
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pmid:26183715
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pmid:26207321
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pmid:26372186
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pmid:26863882
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Shukla S et al. |
Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis. |
2016 |
Sci Rep |
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pmid:27145940
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Cai F et al. |
Cucurbitacin B reverses multidrug resistance by targeting CIP2A to reactivate protein phosphatase 2A in MCF-7/adriamycin cells. |
2016 |
Oncol. Rep. |
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Niu Y et al. |
PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells. |
2016 |
Oxid Med Cell Longev |
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pmid:28108377
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Kim SH et al. |
Doxorubicin has a synergistic cytotoxicity with cucurbitacin B in anaplastic thyroid carcinoma cells. |
2017 |
Tumour Biol. |
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Hua S et al. |
Protective Effects of Cucurbitacin B on Acute Lung Injury Induced by Sepsis in Rats. |
2017 |
Med. Sci. Monit. |
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