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Protective Effects of Cucurbitacin B on Acute Lung Injury Induced by Sepsis in Rats. |
2017 |
Med. Sci. Monit. |
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Doxorubicin has a synergistic cytotoxicity with cucurbitacin B in anaplastic thyroid carcinoma cells. |
2017 |
Tumour Biol. |
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Cai F et al. |
Cucurbitacin B reverses multidrug resistance by targeting CIP2A to reactivate protein phosphatase 2A in MCF-7/adriamycin cells. |
2016 |
Oncol. Rep. |
pmid:27350399
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Niu Y et al. |
PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells. |
2016 |
Oxid Med Cell Longev |
pmid:28042385
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Shukla S et al. |
Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis. |
2016 |
Sci Rep |
pmid:26905250
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Shukla S et al. |
Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis. |
2015 |
Cancer Prev Res (Phila) |
pmid:25813524
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Silva IT et al. |
In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B. |
2015 |
PLoS ONE |
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Lv Q et al. |
Application of spray granulation for conversion of mixed phospholipid-bile salt micelles to dry powder form: influence of drug hydrophobicity on nanoparticle reagglomeration. |
2014 |
Int J Nanomedicine |
pmid:24531119
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Husen A and Siddiqi KS |
Carbon and fullerene nanomaterials in plant system. |
2014 |
J Nanobiotechnology |
pmid:24766786
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Guo J et al. |
Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner. |
2014 |
PLoS ONE |
pmid:24505404
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Gao Y et al. |
Inactivation of ATP citrate lyase by Cucurbitacin B: A bioactive compound from cucumber, inhibits prostate cancer growth. |
2014 |
Cancer Lett. |
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Seo CR et al. |
Cucurbitacin B and cucurbitacin I suppress adipocyte differentiation through inhibition of STAT3 signaling. |
2014 |
Food Chem. Toxicol. |
pmid:24316209
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Ma J et al. |
Cucurbitacin B inhibits the translational expression of hypoxia-inducible factor-1α. |
2014 |
Eur. J. Pharmacol. |
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[Preparation and characterization of cucurbitacin B sodium deoxycholate/phospholipid-mixed oral fast dissolving film and antitumor activity study]. |
2014 |
Zhongguo Zhong Yao Za Zhi |
pmid:25282885
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Shang Y et al. |
Cucurbitacin-B inhibits neuroblastoma cell proliferation through up-regulation of PTEN. |
2014 |
Eur Rev Med Pharmacol Sci |
pmid:25487942
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Zhang M et al. |
Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells. |
2014 |
Mol Med Rep |
pmid:25242136
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Gupta P and Srivastava SK |
Inhibition of Integrin-HER2 signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression. |
2014 |
Oncotarget |
pmid:24729020
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Zhang YT et al. |
VASP activation via the Gα13/RhoA/PKA pathway mediates cucurbitacin-B-induced actin aggregation and cofilin-actin rod formation. |
2014 |
PLoS ONE |
pmid:24691407
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Kole C et al. |
Nanobiotechnology can boost crop production and quality: first evidence from increased plant biomass, fruit yield and phytomedicine content in bitter melon (Momordica charantia). |
2013 |
BMC Biotechnol. |
pmid:23622112
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Hu H et al. |
Preparation, characterization, cellular uptake and evaluation in vivo of solid lipid nanoparticles loaded with cucurbitacin B. |
2013 |
Drug Dev Ind Pharm |
pmid:22794139
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Duportets L et al. |
Steroid hormone signaling is involved in the age-dependent behavioral response to sex pheromone in the adult male moth Agrotis ipsilon. |
2013 |
Gen. Comp. Endocrinol. |
pmid:23474331
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Promkan M et al. |
The effectiveness of cucurbitacin B in BRCA1 defective breast cancer cells. |
2013 |
PLoS ONE |
pmid:23393598
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Kausar H et al. |
Cucurbitacin B potently suppresses non-small-cell lung cancer growth: identification of intracellular thiols as critical targets. |
2013 |
Cancer Lett. |
pmid:23340170
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Jianbo G et al. |
The anti-melanoma efficiency of the intratumoral injection of cucurbitacin-loaded sustained-release carriers: a PLGA particle system. |
2013 |
J Pharm Sci |
pmid:23729371
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Aribi A et al. |
The triterpenoid cucurbitacin B augments the antiproliferative activity of chemotherapy in human breast cancer. |
2013 |
Int. J. Cancer |
pmid:23165325
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Dakeng S et al. |
Inhibition of Wnt signaling by cucurbitacin B in breast cancer cells: reduction of Wnt-associated proteins and reduced translocation of galectin-3-mediated β-catenin to the nucleus. |
2012 |
J. Cell. Biochem. |
pmid:21866566
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Lu P et al. |
Cucurbitacin B regulates immature myeloid cell differentiation and enhances antitumor immunity in patients with lung cancer. |
2012 |
Cancer Biother. Radiopharm. |
pmid:22746287
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Lang KL et al. |
Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives. |
2012 |
Bioorg. Med. Chem. |
pmid:22472043
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Zhang T et al. |
Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis. |
2012 |
Autophagy |
pmid:22441021
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Zhu JS et al. |
Cucurbitacin B induces cell cycle arrest, apoptosis and autophagy associated with G actin reduction and persistent activation of cofilin in Jurkat cells. |
2012 |
Pharmacology |
pmid:22699368
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Duangmano S et al. |
Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation. |
2012 |
BMC Complement Altern Med |
pmid:23062075
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Zhang Y et al. |
Cucurbitacin B induces rapid depletion of the G-actin pool through reactive oxygen species-dependent actin aggregation in melanoma cells. |
2011 |
Acta Biochim. Biophys. Sin. (Shanghai) |
pmid:21642275
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Ouyang D et al. |
Histone deacetylase inhibitor valproic acid sensitizes B16F10 melanoma cells to cucurbitacin B treatment. |
2011 |
Acta Biochim. Biophys. Sin. (Shanghai) |
pmid:21628505
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Jin HR et al. |
Cucurbitacin B suppresses the transactivation activity of RelA/p65. |
2011 |
J. Cell. Biochem. |
pmid:21344491
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Wei Y et al. |
[Studies on chemical constituents in roots of Helicteres angustifolia]. |
2011 |
Zhongguo Zhong Yao Za Zhi |
pmid:21842648
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Lee DH et al. |
Synergistic effect of low-dose cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma. |
2011 |
Cancer Lett. |
pmid:21440986
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Jung ME and Lui RM |
Studies toward the total syntheses of cucurbitacins B and D. |
2010 |
J. Org. Chem. |
pmid:20873743
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Chen W et al. |
Cucurbitacin B inhibits growth, arrests the cell cycle, and potentiates antiproliferative efficacy of cisplatin in cutaneous squamous cell carcinoma cell lines. |
2010 |
Int. J. Oncol. |
pmid:20664943
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Chan KT et al. |
Cucurbitacin B inhibits STAT3 and the Raf/MEK/ERK pathway in leukemia cell line K562. |
2010 |
Cancer Lett. |
pmid:19700240
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Nakashima S et al. |
Cucurbitacin E as a new inhibitor of cofilin phosphorylation in human leukemia U937 cells. |
2010 |
Bioorg. Med. Chem. Lett. |
pmid:20347305
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Yasuda S et al. |
Cucurbitacin B induces G2 arrest and apoptosis via a reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells. |
2010 |
Mol Nutr Food Res |
pmid:19937855
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Liu T et al. |
Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin. |
2010 |
Eur. J. Pharmacol. |
pmid:20483353
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Dat NT et al. |
An isoaurone and other constituents from Trichosanthes kirilowii seeds inhibit hypoxia-inducible factor-1 and nuclear factor-kappaB. |
2010 |
J. Nat. Prod. |
pmid:20469887
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Iwanski GB et al. |
Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer. |
2010 |
Br. J. Pharmacol. |
pmid:20590594
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Zhang M et al. |
Inhibition of pancreatic cancer cell growth by cucurbitacin B through modulation of signal transducer and activator of transcription 3 signaling. |
2010 |
Pancreas |
pmid:20182390
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Wang W et al. |
Galactosylated solid lipid nanoparticles with cucurbitacin B improves the liver targetability. |
2010 |
Drug Deliv |
pmid:20148709
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Duangmano S et al. |
Antiproliferative effects of cucurbitacin B in breast cancer cells: down-regulation of the c-Myc/hTERT/telomerase pathway and obstruction of the cell cycle. |
2010 |
Int J Mol Sci |
pmid:21614210
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Chen C et al. |
Cucurbitane-type triterpenoids from the stems of Cucumis melo. |
2009 |
J. Nat. Prod. |
pmid:19348465
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Kongtun S et al. |
Cytotoxic properties of root extract and fruit juice of Trichosanthes cucumerina. |
2009 |
Planta Med. |
pmid:19288406
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Zhang M et al. |
Targeted constitutive activation of signal transducer and activator of transcription 3 in human hepatocellular carcinoma cells by cucurbitacin B. |
2009 |
Cancer Chemother. Pharmacol. |
pmid:18521604
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