Cucurbitacin S

Cucurbitacin s is a lipid of Sterol Lipids (ST) class. The involved functions are known as establishment and maintenance of localization and nitric oxide biosynthetic process.

Cross Reference

Introduction

To understand associated biological information of Cucurbitacin S, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Cucurbitacin S

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

What functions are associated with Cucurbitacin S?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

What genes are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Cucurbitacin S

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Authors Title Published Journal PubMed Link
Wang WD et al. ANTITUMOR AND APOPTOTIC EFFECTS OF CUCURBITACIN A IN A-549 LUNG CARCINOMA CELLS IS MEDIATED VIA G2/M CELL CYCLE ARREST AND M-TOR/PI3K/AKT SIGNALLING PATHWAY. 2017 Afr J Tradit Complement Altern Med pmid:28573224
Chawech R et al. Cucurbitacins from the Leaves of Citrullus colocynthis (L.) Schrad. 2015 Molecules pmid:26437392
Arumuggam N et al. A Review: Phytochemicals Targeting JAK/STAT Signaling and IDO Expression in Cancer. 2015 Phytother Res pmid:25787773
Kuo TC et al. The effect of red light and far-red light conditions on secondary metabolism in agarwood. 2015 BMC Plant Biol. pmid:26067652
Guo J et al. The anti-melanoma efficiency of the intratumoral injection of cucurbitacin-loaded sustained release carriers: in situ-forming implants. 2015 AAPS PharmSciTech pmid:25609378
Davidovich-Rikanati R et al. Recombinant yeast as a functional tool for understanding bitterness and cucurbitacin biosynthesis in watermelon (Citrullus spp.). 2015 Yeast pmid:25308777
Theis N et al. Attracting mutualists and antagonists: plant trait variation explains the distribution of specialist floral herbivores and pollinators on crops and wild gourds. 2014 Am. J. Bot. pmid:25156980
Chen CH et al. Identification of cucurbitacins and assembly of a draft genome for Aquilaria agallocha. 2014 BMC Genomics pmid:25005802
Muchtaridi M et al. Potential activity of fevicordin-A from Phaleria macrocarpa (Scheff) Boerl. seeds as estrogen receptor antagonist based on cytotoxicity and molecular modelling studies. 2014 Int J Mol Sci pmid:24776765
Wang Y et al. Cucurbitacin IIb exhibits anti-inflammatory activity through modulating multiple cellular behaviors of mouse lymphocytes. 2014 PLoS ONE pmid:24587010
Bai M et al. Development and validation of an LC-ESI-MS/MS method for the quantitation of hemslecin A in rhesus monkey plasma and its application in pharmacokinetics. 2014 Biomed. Chromatogr. pmid:24132644
Lang KL et al. Multivariate SAR and QSAR of cucurbitacin derivatives as cytotoxic compounds in a human lung adenocarcinoma cell line. 2014 J. Mol. Graph. Model. pmid:24378396
Ahmed MS and Halaweish FT Cucurbitacins: potential candidates targeting mitogen-activated protein kinase pathway for treatment of melanoma. 2014 J Enzyme Inhib Med Chem pmid:23368732
Hira SK et al. Downregulation of endogenous STAT3 augments tumoricidal activity of interleukin 15 activated dendritic cell against lymphoma and leukemia via TRAIL. 2014 Exp. Cell Res. pmid:25139620
Xu XT et al. [Study on in vivo pharmacokinetics of cucurbitacin injection in rats]. 2014 Zhongguo Zhong Yao Za Zhi pmid:25272856
Zhang S et al. Localization of a new gene for bitterness in cucumber. 2013 Jan-Feb J. Hered. pmid:23091223
Lang KL et al. Chemical modification produces species-specific changes in cucurbitacin antifeedant effect. 2013 J. Agric. Food Chem. pmid:23646892
Zhang YT et al. Formation of cofilin-actin rods following cucurbitacin-B-induced actin aggregation depends on Slingshot homolog 1-mediated cofilin hyperactivation. 2013 J. Cell. Biochem. pmid:23695982
Guo RH et al. Synthesis of hemslecin A derivatives: a new class of hepatitis B virus inhibitors. 2013 Bioorg. Med. Chem. Lett. pmid:23385212
He J et al. Cucurbitacin IIa induces caspase-3-dependent apoptosis and enhances autophagy in lipopolysaccharide-stimulated RAW 264.7 macrophages. 2013 Int. Immunopharmacol. pmid:23541744