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pmid:
|
Guo J et al. |
The anti-melanoma efficiency of the intratumoral injection of cucurbitacin-loaded sustained release carriers: in situ-forming implants. |
2015 |
AAPS PharmSciTech |
pmid:25609378
|
Wang WD et al. |
ANTITUMOR AND APOPTOTIC EFFECTS OF CUCURBITACIN A IN A-549 LUNG CARCINOMA CELLS IS MEDIATED VIA G2/M CELL CYCLE ARREST AND M-TOR/PI3K/AKT SIGNALLING PATHWAY. |
2017 |
Afr J Tradit Complement Altern Med |
pmid:28573224
|
Theis N et al. |
Attracting mutualists and antagonists: plant trait variation explains the distribution of specialist floral herbivores and pollinators on crops and wild gourds. |
2014 |
Am. J. Bot. |
pmid:25156980
|
Yang PQ et al. |
Cucurbitacin contents in Hemsleya dolichocarpa. |
1991 |
Am. J. Chin. Med. |
pmid:1897490
|
Chen X et al. |
Biological activities and potential molecular targets of cucurbitacins: a focus on cancer. |
2012 |
Anticancer Drugs |
pmid:22561419
|
Henrich CJ et al. |
Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis. |
2012 |
Apoptosis |
pmid:21928090
|
Tannin-Spitz T et al. |
Cucurbitacin glucosides: antioxidant and free-radical scavenging activities. |
2007 |
Biochem. Biophys. Res. Commun. |
pmid:17942079
|
Witkowski A et al. |
Inhibition of the biosynthesis of deoxyribonucleic acid, ribonucleic acid and protein in HeLa S3 cells by cucurbitacins, glucocorticoid-like cytotoxic triterpenes. |
1984 |
Biochem. Pharmacol. |
pmid:6546879
|
Witkowski A and Konopa J |
Binding of the cytotoxic and antitumor triterpenes, cucurbitacins, to glucocorticoid receptors of HeLa cells. |
1981 |
Biochim. Biophys. Acta |
pmid:6894552
|
Patel SK et al. |
Roles of nonpolar and polar intermolecular interactions in the improvement of the drug loading capacity of PEO-b-PCL with increasing PCL content for two hydrophobic Cucurbitacin drugs. |
2009 |
Biomacromolecules |
pmid:19655789
|
Patel SK et al. |
Prediction of the solubility of cucurbitacin drugs in self-associating poly(ethylene oxide)-b-poly(alpha-benzyl carboxylate epsilon-caprolactone) block copolymer with different tacticities using molecular dynamics simulation. |
2010 |
Biomaterials |
pmid:19796808
|
Patel SK et al. |
Molecular dynamics study of the encapsulation capability of a PCL-PEO based block copolymer for hydrophobic drugs with different spatial distributions of hydrogen bond donors and acceptors. |
2010 |
Biomaterials |
pmid:19962756
|
Bai M et al. |
Development and validation of an LC-ESI-MS/MS method for the quantitation of hemslecin A in rhesus monkey plasma and its application in pharmacokinetics. |
2014 |
Biomed. Chromatogr. |
pmid:24132644
|
Bartalis J and Halaweish FT |
In vitro and QSAR studies of cucurbitacins on HepG2 and HSC-T6 liver cell lines. |
2011 |
Bioorg. Med. Chem. |
pmid:21459003
|
Ramalhete C et al. |
New potent P-glycoprotein modulators with the cucurbitane scaffold and their synergistic interaction with doxorubicin on resistant cancer cells. |
2009 |
Bioorg. Med. Chem. |
pmid:19733087
|
Guo RH et al. |
Synthesis of hemslecin A derivatives: a new class of hepatitis B virus inhibitors. |
2013 |
Bioorg. Med. Chem. Lett. |
pmid:23385212
|
Chen CH et al. |
Identification of cucurbitacins and assembly of a draft genome for Aquilaria agallocha. |
2014 |
BMC Genomics |
pmid:25005802
|
Kuo TC et al. |
The effect of red light and far-red light conditions on secondary metabolism in agarwood. |
2015 |
BMC Plant Biol. |
pmid:26067652
|
Boykin C et al. |
Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation. |
2011 |
Br. J. Cancer |
pmid:21304528
|
Ren S et al. |
Anti-proliferative effect of 23,24-dihydrocucurbitacin F on human prostate cancer cells through induction of actin aggregation and cofilin-actin rod formation. |
2012 |
Cancer Chemother. Pharmacol. |
pmid:22814677
|
Jayaprakasam B et al. |
Anticancer and antiinflammatory activities of cucurbitacins from Cucurbita andreana. |
2003 |
Cancer Lett. |
pmid:12445672
|
GALLILY R et al. |
Further studies on the antitumor effect of cucurbitacins. |
1962 |
Cancer Res. |
pmid:13946249
|
Gabrielsen M et al. |
Cucurbitacin covalent bonding to cysteine thiols: the filamentous-actin severing protein Cofilin1 as an exemplary target. |
2013 |
Cell Commun. Signal |
pmid:23945128
|
Dinan L et al. |
Assessment of natural products in the Drosophila melanogaster B(II) cell bioassay for ecdysteroid agonist and antagonist activities. |
2001 |
Cell. Mol. Life Sci. |
pmid:11289314
|
Himeno E et al. |
Structures of cayaponosides A, B, C and D, glucosides of new nor-cucurbitacins in the roots of Cayaponia tayuya. |
1992 |
Chem. Pharm. Bull. |
pmid:1464123
|
Kawahara N et al. |
Two new cucurbitacin glucosides, opercurins A and B, from the Brazilian folk medicine "Buchinha" (Luffa operculata). |
2004 |
Chem. Pharm. Bull. |
pmid:15305007
|
Shaw JT and Hummel HE |
A monitoring trap for Diabrotica virgifera virgifera and D. barberi adults lured with a poisoned cucurbitacin bait. |
2003 |
Commun. Agric. Appl. Biol. Sci. |
pmid:15149093
|
RÃos JL et al. |
Cucurbitacins as inducers of cell death and a rich source of potential anticancer compounds. |
2012 |
Curr. Pharm. Des. |
pmid:22443631
|
Ayyad SE et al. |
In vitro and in vivo study of cucurbitacins-type triterpene glucoside from Citrullus colocynthis growing in Saudi Arabia against hepatocellular carcinoma. |
2012 |
Environ. Toxicol. Pharmacol. |
pmid:22245841
|
Hira SK et al. |
Downregulation of endogenous STAT3 augments tumoricidal activity of interleukin 15 activated dendritic cell against lymphoma and leukemia via TRAIL. |
2014 |
Exp. Cell Res. |
pmid:25139620
|
Attard EG and Scicluna-Spiteri A |
Ecballium elaterium: an in vitro source of cucurbitacins. |
2001 |
Fitoterapia |
pmid:11163940
|
Kirschman JC and Suber RL |
Recent food poisonings from cucurbitacin in traditionally bred squash. |
1989 |
Food Chem. Toxicol. |
pmid:2792979
|
Yang K et al. |
[Clinical application of anticancer nanoparticles targeting metastasis foci of cervical lymph nodes in patients with oral carcinoma]. |
2003 |
Hua Xi Kou Qiang Yi Xue Za Zhi |
pmid:14732978
|