Cucurbitacin S

Cucurbitacin s is a lipid of Sterol Lipids (ST) class. The involved functions are known as establishment and maintenance of localization and nitric oxide biosynthetic process.

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Introduction

To understand associated biological information of Cucurbitacin S, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Cucurbitacin S

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

What functions are associated with Cucurbitacin S?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

What genes are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Cucurbitacin S

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Authors Title Published Journal PubMed Link
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Attard EG and Scicluna-Spiteri A Ecballium elaterium: an in vitro source of cucurbitacins. 2001 Fitoterapia pmid:11163940
Dinan L et al. Assessment of natural products in the Drosophila melanogaster B(II) cell bioassay for ecdysteroid agonist and antagonist activities. 2001 Cell. Mol. Life Sci. pmid:11289314
Behle RW Consumption of residue containing cucurbitacin feeding stimulant and reduced rates of carbaryl insecticide by western corn rootworm (Coleoptera: Chrysomelidae). 2001 J. Econ. Entomol. pmid:11777045
Ito A et al. Ellagic acid derivatives and cytotoxic cucurbitacins from Elaeocarpus mastersii. 2002 Phytochemistry pmid:12169311
Jayaprakasam B et al. Anticancer and antiinflammatory activities of cucurbitacins from Cucurbita andreana. 2003 Cancer Lett. pmid:12445672
Li CY and Hou SX [A study on lyophilization injection of cucurbitacin polylactic acid nanoparticles]. 2001 Zhongguo Zhong Yao Za Zhi pmid:12528519
Gillespie JJ et al. Convergent evolution of cucurbitacin feeding in spatially isolated rootworm taxa (Coleoptera: Chrysomelidae; Galerucinae, Luperini). 2003 Mol. Phylogenet. Evol. pmid:12967617
GALLILY R et al. Further studies on the antitumor effect of cucurbitacins. 1962 Cancer Res. pmid:13946249
Himeno E et al. Structures of cayaponosides A, B, C and D, glucosides of new nor-cucurbitacins in the roots of Cayaponia tayuya. 1992 Chem. Pharm. Bull. pmid:1464123
Yang K et al. [Clinical application of anticancer nanoparticles targeting metastasis foci of cervical lymph nodes in patients with oral carcinoma]. 2003 Hua Xi Kou Qiang Yi Xue Za Zhi pmid:14732978
Yang K et al. [The study of cucurbitacin BE polylactic acid nanoparticles delivering cucurbitacin BE to metastasized cervical lymph nodes in mice with oral cancer]. 2003 Hua Xi Kou Qiang Yi Xue Za Zhi pmid:14732987
Martin PA and Blackburn M Inhibition of seed germination by extracts of bitter Hawkesbury watermelon containing cucurbitacin, a feeding stimulant for corn rootworm (Coleoptera: Chrysomelidae). 2003 J. Econ. Entomol. pmid:14994812
Recio MC et al. Anti-inflammatory activity of two cucurbitacins isolated from Cayaponia tayuya roots. 2004 Planta Med. pmid:15124085
Shaw JT and Hummel HE A monitoring trap for Diabrotica virgifera virgifera and D. barberi adults lured with a poisoned cucurbitacin bait. 2003 Commun. Agric. Appl. Biol. Sci. pmid:15149093
Kawahara N et al. Two new cucurbitacin glucosides, opercurins A and B, from the Brazilian folk medicine "Buchinha" (Luffa operculata). 2004 Chem. Pharm. Bull. pmid:15305007
Siegfried BD et al. Monitoring western corn rootworm (Coleoptera: Chrysomelidae) susceptibility to carbaryl and cucurbitacin baits in the areawide management pilot program. 2004 J. Econ. Entomol. pmid:15568365
Bartalis J and Halaweish FT Relationship between cucurbitacins reversed-phase high-performance liquid chromatography hydrophobicity index and basal cytotoxicity on HepG2 cells. 2005 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:15734155
Sun J et al. Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity. 2005 Oncogene pmid:15735720
Seger C et al. 1H and 13C NMR signal assignment of cucurbitacin derivatives from Citrullus colocynthis (L.) Schrader and Ecballium elaterium L. (Cucurbitaceae). 2005 Magn Reson Chem pmid:15772995
Zhang JF et al. [The preparation of the polylacticacid nanoparticles of cucurbitacin and their drug loading]. 2005 Zhongguo Zhong Yao Za Zhi pmid:15810448
Yang X et al. [Relationships of Aulacophora beetles feeding behavior with cucurbitacin types in host crops]. 2005 Ying Yong Sheng Tai Xue Bao pmid:16252877
Nayab D et al. Cucurbitacin glucosides from Citrullus colocynthis. 2006 Nat. Prod. Res. pmid:16644537
Zou JM et al. A new cucurbitacin from Picria fel-terrae. 2006 J Asian Nat Prod Res pmid:16864449
Allen JG et al. The bioactivity-guided isolation and structural identification of toxic cucurbitacin steroidal glucosides from stemodia kingii. 2006 Jul-Aug Phytochem Anal pmid:16910038
Escandell JM et al. Cucurbitacin R reduces the inflammation and bone damage associated with adjuvant arthritis in lewis rats by suppression of tumor necrosis factor-alpha in T lymphocytes and macrophages. 2007 J. Pharmacol. Exp. Ther. pmid:17065367
Kim IH et al. Iridoid glycosides and cucurbitacin glycoside from Neopicrorhiza scrophulariiflora. 2006 Phytochemistry pmid:17070880
Chaves DC et al. Cucurbitacins from Cayaponia racemosa: isolation and total assignment of 1H and 13C NMR spectra. 2007 Magn Reson Chem pmid:17372957
Bhandari P et al. Cucurbitacins from Bacopa monnieri. 2007 Phytochemistry pmid:17442350
Zheng CH et al. A new cucurbitacin from Bolbostemma paniculatum Franguent. 2007 J Asian Nat Prod Res pmid:17454317
Zhang JF et al. [Comparison of preparing two polylactide nanoparticles loaded lipophilic anti-cancer herb drug by nanoprecipitation method]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17455462
Molavi O et al. Polymeric micelles for the solubilization and delivery of STAT3 inhibitor cucurbitacins in solid tumors. 2008 Int J Pharm pmid:17681440
Tannin-Spitz T et al. Cucurbitacin glucosides: antioxidant and free-radical scavenging activities. 2007 Biochem. Biophys. Res. Commun. pmid:17942079
Chen J et al. Trinorcucurbitane and cucurbitane triterpenoids from the roots of Momordica charantia. 2008 Phytochemistry pmid:18045630
Rao VS et al. Evaluation of the purified fraction of Wilbrandia (c.f.) verticillata for antitumour activity. 1991 Mem. Inst. Oswaldo Cruz pmid:1842011
Beurel E and Jope RS Differential regulation of STAT family members by glycogen synthase kinase-3. 2008 J. Biol. Chem. pmid:18550525
Maloney KN et al. Actin-aggregating cucurbitacins from Physocarpus capitatus. 2008 J. Nat. Prod. pmid:18959442
Yang PQ et al. Cucurbitacin contents in Hemsleya dolichocarpa. 1991 Am. J. Chin. Med. pmid:1897490
Abou-Khalil R et al. Interaction of cucurbitacins with human serum albumin: Thermodynamic characteristics and influence on the binding of site specific ligands. 2009 J. Photochem. Photobiol. B, Biol. pmid:19380237
Patel SK et al. Roles of nonpolar and polar intermolecular interactions in the improvement of the drug loading capacity of PEO-b-PCL with increasing PCL content for two hydrophobic Cucurbitacin drugs. 2009 Biomacromolecules pmid:19655789
Ramalhete C et al. New potent P-glycoprotein modulators with the cucurbitane scaffold and their synergistic interaction with doxorubicin on resistant cancer cells. 2009 Bioorg. Med. Chem. pmid:19733087
Patel SK et al. Prediction of the solubility of cucurbitacin drugs in self-associating poly(ethylene oxide)-b-poly(alpha-benzyl carboxylate epsilon-caprolactone) block copolymer with different tacticities using molecular dynamics simulation. 2010 Biomaterials pmid:19796808
Patel SK et al. Molecular dynamics study of the encapsulation capability of a PCL-PEO based block copolymer for hydrophobic drugs with different spatial distributions of hydrogen bond donors and acceptors. 2010 Biomaterials pmid:19962756
Lee DH et al. Cucurbitacin: ancient compound shedding new light on cancer treatment. 2010 ScientificWorldJournal pmid:20209387
Boykin C et al. Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation. 2011 Br. J. Cancer pmid:21304528
Bartalis J and Halaweish FT In vitro and QSAR studies of cucurbitacins on HepG2 and HSC-T6 liver cell lines. 2011 Bioorg. Med. Chem. pmid:21459003
Lang KL et al. New cytotoxic cucurbitacins from Wilbrandia ebracteata Cogn. 2011 Planta Med. pmid:21472651
Pedersen AB and Godfrey LD Evaluation of cucurbitacin-based gustatory stimulant to facilitate cucumber beetle (Coleoptera: Chrysomelidae) management with foliar insecticides in melons. 2011 J. Econ. Entomol. pmid:21882695
Henrich CJ et al. Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis. 2012 Apoptosis pmid:21928090
Pan L et al. Isolation, structure elucidation, and biological evaluation of 16,23-epoxycucurbitacin constituents from Eleaocarpus chinensis. 2012 J. Nat. Prod. pmid:22239601