Cucurbitacin S

Cucurbitacin s is a lipid of Sterol Lipids (ST) class. The involved functions are known as establishment and maintenance of localization and nitric oxide biosynthetic process.

Cross Reference

Introduction

To understand associated biological information of Cucurbitacin S, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Cucurbitacin S

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

What functions are associated with Cucurbitacin S?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

What genes are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Cucurbitacin S?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Cucurbitacin S

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Authors Title Published Journal PubMed Link
Abbas S et al. The cucurbitacins E, D and I: investigation of their cytotoxicity toward human chondrosarcoma SW 1353 cell line and their biotransformation in man liver. 2013 Toxicol. Lett. pmid:23194827
Gabrielsen M et al. Cucurbitacin covalent bonding to cysteine thiols: the filamentous-actin severing protein Cofilin1 as an exemplary target. 2013 Cell Commun. Signal pmid:23945128
Ayyad SE et al. In vitro and in vivo study of cucurbitacins-type triterpene glucoside from Citrullus colocynthis growing in Saudi Arabia against hepatocellular carcinoma. 2012 Environ. Toxicol. Pharmacol. pmid:22245841
Pan L et al. Isolation, structure elucidation, and biological evaluation of 16,23-epoxycucurbitacin constituents from Eleaocarpus chinensis. 2012 J. Nat. Prod. pmid:22239601
Henrich CJ et al. Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis. 2012 Apoptosis pmid:21928090
Chen X et al. Biological activities and potential molecular targets of cucurbitacins: a focus on cancer. 2012 Anticancer Drugs pmid:22561419
Ren S et al. Anti-proliferative effect of 23,24-dihydrocucurbitacin F on human prostate cancer cells through induction of actin aggregation and cofilin-actin rod formation. 2012 Cancer Chemother. Pharmacol. pmid:22814677
Ríos JL et al. Cucurbitacins as inducers of cell death and a rich source of potential anticancer compounds. 2012 Curr. Pharm. Des. pmid:22443631
Bartalis J and Halaweish FT In vitro and QSAR studies of cucurbitacins on HepG2 and HSC-T6 liver cell lines. 2011 Bioorg. Med. Chem. pmid:21459003
Lang KL et al. New cytotoxic cucurbitacins from Wilbrandia ebracteata Cogn. 2011 Planta Med. pmid:21472651
Boykin C et al. Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation. 2011 Br. J. Cancer pmid:21304528
Pedersen AB and Godfrey LD Evaluation of cucurbitacin-based gustatory stimulant to facilitate cucumber beetle (Coleoptera: Chrysomelidae) management with foliar insecticides in melons. 2011 J. Econ. Entomol. pmid:21882695
Lee DH et al. Cucurbitacin: ancient compound shedding new light on cancer treatment. 2010 ScientificWorldJournal pmid:20209387
Patel SK et al. Prediction of the solubility of cucurbitacin drugs in self-associating poly(ethylene oxide)-b-poly(alpha-benzyl carboxylate epsilon-caprolactone) block copolymer with different tacticities using molecular dynamics simulation. 2010 Biomaterials pmid:19796808
Patel SK et al. Molecular dynamics study of the encapsulation capability of a PCL-PEO based block copolymer for hydrophobic drugs with different spatial distributions of hydrogen bond donors and acceptors. 2010 Biomaterials pmid:19962756
Ramalhete C et al. New potent P-glycoprotein modulators with the cucurbitane scaffold and their synergistic interaction with doxorubicin on resistant cancer cells. 2009 Bioorg. Med. Chem. pmid:19733087
Patel SK et al. Roles of nonpolar and polar intermolecular interactions in the improvement of the drug loading capacity of PEO-b-PCL with increasing PCL content for two hydrophobic Cucurbitacin drugs. 2009 Biomacromolecules pmid:19655789
Abou-Khalil R et al. Interaction of cucurbitacins with human serum albumin: Thermodynamic characteristics and influence on the binding of site specific ligands. 2009 J. Photochem. Photobiol. B, Biol. pmid:19380237
Maloney KN et al. Actin-aggregating cucurbitacins from Physocarpus capitatus. 2008 J. Nat. Prod. pmid:18959442
Chen J et al. Trinorcucurbitane and cucurbitane triterpenoids from the roots of Momordica charantia. 2008 Phytochemistry pmid:18045630