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1H and 13C NMR signal assignment of cucurbitacin derivatives from Citrullus colocynthis (L.) Schrader and Ecballium elaterium L. (Cucurbitaceae). |
2005 |
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[The preparation of the polylacticacid nanoparticles of cucurbitacin and their drug loading]. |
2005 |
Zhongguo Zhong Yao Za Zhi |
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[Relationships of Aulacophora beetles feeding behavior with cucurbitacin types in host crops]. |
2005 |
Ying Yong Sheng Tai Xue Bao |
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Relationship between cucurbitacins reversed-phase high-performance liquid chromatography hydrophobicity index and basal cytotoxicity on HepG2 cells. |
2005 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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A new cucurbitacin from Picria fel-terrae. |
2006 |
J Asian Nat Prod Res |
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2006 |
Phytochemistry |
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Cucurbitacin glucosides from Citrullus colocynthis. |
2006 |
Nat. Prod. Res. |
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The bioactivity-guided isolation and structural identification of toxic cucurbitacin steroidal glucosides from stemodia kingii. |
2006 Jul-Aug |
Phytochem Anal |
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Cucurbitacins from Cayaponia racemosa: isolation and total assignment of 1H and 13C NMR spectra. |
2007 |
Magn Reson Chem |
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Cucurbitacins from Bacopa monnieri. |
2007 |
Phytochemistry |
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A new cucurbitacin from Bolbostemma paniculatum Franguent. |
2007 |
J Asian Nat Prod Res |
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[Comparison of preparing two polylactide nanoparticles loaded lipophilic anti-cancer herb drug by nanoprecipitation method]. |
2007 |
Zhongguo Zhong Yao Za Zhi |
pmid:17455462
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Cucurbitacin glucosides: antioxidant and free-radical scavenging activities. |
2007 |
Biochem. Biophys. Res. Commun. |
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Cucurbitacin R reduces the inflammation and bone damage associated with adjuvant arthritis in lewis rats by suppression of tumor necrosis factor-alpha in T lymphocytes and macrophages. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17065367
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Actin-aggregating cucurbitacins from Physocarpus capitatus. |
2008 |
J. Nat. Prod. |
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Trinorcucurbitane and cucurbitane triterpenoids from the roots of Momordica charantia. |
2008 |
Phytochemistry |
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Differential regulation of STAT family members by glycogen synthase kinase-3. |
2008 |
J. Biol. Chem. |
pmid:18550525
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Polymeric micelles for the solubilization and delivery of STAT3 inhibitor cucurbitacins in solid tumors. |
2008 |
Int J Pharm |
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New potent P-glycoprotein modulators with the cucurbitane scaffold and their synergistic interaction with doxorubicin on resistant cancer cells. |
2009 |
Bioorg. Med. Chem. |
pmid:19733087
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Roles of nonpolar and polar intermolecular interactions in the improvement of the drug loading capacity of PEO-b-PCL with increasing PCL content for two hydrophobic Cucurbitacin drugs. |
2009 |
Biomacromolecules |
pmid:19655789
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Interaction of cucurbitacins with human serum albumin: Thermodynamic characteristics and influence on the binding of site specific ligands. |
2009 |
J. Photochem. Photobiol. B, Biol. |
pmid:19380237
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Cucurbitacin: ancient compound shedding new light on cancer treatment. |
2010 |
ScientificWorldJournal |
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Prediction of the solubility of cucurbitacin drugs in self-associating poly(ethylene oxide)-b-poly(alpha-benzyl carboxylate epsilon-caprolactone) block copolymer with different tacticities using molecular dynamics simulation. |
2010 |
Biomaterials |
pmid:19796808
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Molecular dynamics study of the encapsulation capability of a PCL-PEO based block copolymer for hydrophobic drugs with different spatial distributions of hydrogen bond donors and acceptors. |
2010 |
Biomaterials |
pmid:19962756
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Bartalis J and Halaweish FT |
In vitro and QSAR studies of cucurbitacins on HepG2 and HSC-T6 liver cell lines. |
2011 |
Bioorg. Med. Chem. |
pmid:21459003
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New cytotoxic cucurbitacins from Wilbrandia ebracteata Cogn. |
2011 |
Planta Med. |
pmid:21472651
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Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation. |
2011 |
Br. J. Cancer |
pmid:21304528
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Evaluation of cucurbitacin-based gustatory stimulant to facilitate cucumber beetle (Coleoptera: Chrysomelidae) management with foliar insecticides in melons. |
2011 |
J. Econ. Entomol. |
pmid:21882695
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In vitro and in vivo study of cucurbitacins-type triterpene glucoside from Citrullus colocynthis growing in Saudi Arabia against hepatocellular carcinoma. |
2012 |
Environ. Toxicol. Pharmacol. |
pmid:22245841
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Isolation, structure elucidation, and biological evaluation of 16,23-epoxycucurbitacin constituents from Eleaocarpus chinensis. |
2012 |
J. Nat. Prod. |
pmid:22239601
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Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis. |
2012 |
Apoptosis |
pmid:21928090
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Biological activities and potential molecular targets of cucurbitacins: a focus on cancer. |
2012 |
Anticancer Drugs |
pmid:22561419
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Anti-proliferative effect of 23,24-dihydrocucurbitacin F on human prostate cancer cells through induction of actin aggregation and cofilin-actin rod formation. |
2012 |
Cancer Chemother. Pharmacol. |
pmid:22814677
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Cucurbitacins as inducers of cell death and a rich source of potential anticancer compounds. |
2012 |
Curr. Pharm. Des. |
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The cucurbitacins E, D and I: investigation of their cytotoxicity toward human chondrosarcoma SW 1353 cell line and their biotransformation in man liver. |
2013 |
Toxicol. Lett. |
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Chemical modification produces species-specific changes in cucurbitacin antifeedant effect. |
2013 |
J. Agric. Food Chem. |
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Formation of cofilin-actin rods following cucurbitacin-B-induced actin aggregation depends on Slingshot homolog 1-mediated cofilin hyperactivation. |
2013 |
J. Cell. Biochem. |
pmid:23695982
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Synthesis of hemslecin A derivatives: a new class of hepatitis B virus inhibitors. |
2013 |
Bioorg. Med. Chem. Lett. |
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Cucurbitacin IIa induces caspase-3-dependent apoptosis and enhances autophagy in lipopolysaccharide-stimulated RAW 264.7 macrophages. |
2013 |
Int. Immunopharmacol. |
pmid:23541744
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Cucurbitacin covalent bonding to cysteine thiols: the filamentous-actin severing protein Cofilin1 as an exemplary target. |
2013 |
Cell Commun. Signal |
pmid:23945128
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Zhang S et al. |
Localization of a new gene for bitterness in cucumber. |
2013 Jan-Feb |
J. Hered. |
pmid:23091223
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Attracting mutualists and antagonists: plant trait variation explains the distribution of specialist floral herbivores and pollinators on crops and wild gourds. |
2014 |
Am. J. Bot. |
pmid:25156980
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Identification of cucurbitacins and assembly of a draft genome for Aquilaria agallocha. |
2014 |
BMC Genomics |
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Potential activity of fevicordin-A from Phaleria macrocarpa (Scheff) Boerl. seeds as estrogen receptor antagonist based on cytotoxicity and molecular modelling studies. |
2014 |
Int J Mol Sci |
pmid:24776765
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Cucurbitacin IIb exhibits anti-inflammatory activity through modulating multiple cellular behaviors of mouse lymphocytes. |
2014 |
PLoS ONE |
pmid:24587010
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Development and validation of an LC-ESI-MS/MS method for the quantitation of hemslecin A in rhesus monkey plasma and its application in pharmacokinetics. |
2014 |
Biomed. Chromatogr. |
pmid:24132644
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Multivariate SAR and QSAR of cucurbitacin derivatives as cytotoxic compounds in a human lung adenocarcinoma cell line. |
2014 |
J. Mol. Graph. Model. |
pmid:24378396
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Ahmed MS and Halaweish FT |
Cucurbitacins: potential candidates targeting mitogen-activated protein kinase pathway for treatment of melanoma. |
2014 |
J Enzyme Inhib Med Chem |
pmid:23368732
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Downregulation of endogenous STAT3 augments tumoricidal activity of interleukin 15 activated dendritic cell against lymphoma and leukemia via TRAIL. |
2014 |
Exp. Cell Res. |
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[Study on in vivo pharmacokinetics of cucurbitacin injection in rats]. |
2014 |
Zhongguo Zhong Yao Za Zhi |
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