4,4-dimethylzymosterol

4,4-dimethylzymosterol is a lipid of Sterol Lipids (ST) class. The involved functions are known as Synthesis, Anabolism, sphingolipid biosynthesis, Permissiveness, Biological Function and ergosterol biosynthesis. 4,4-dimethylzymosterol often locates in Microsomes, Protoplasm and Face. The associated genes with 4,4-dimethylzymosterol are DLC1 gene. The related lipids are Sterols, zymosterol, Cholestenones, coprostanone and Sphingolipids.

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Introduction

To understand associated biological information of 4,4-dimethylzymosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4,4-dimethylzymosterol?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 4,4-dimethylzymosterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with 4,4-dimethylzymosterol?

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What functions are associated with 4,4-dimethylzymosterol?


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What lipids are associated with 4,4-dimethylzymosterol?

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What genes are associated with 4,4-dimethylzymosterol?

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What common seen animal models are associated with 4,4-dimethylzymosterol?

There are no associated biomedical information in the current reference collection.

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All references with 4,4-dimethylzymosterol

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Authors Title Published Journal PubMed Link
pmid:
Aoyama Y et al. Involvement of cytochrome b5 and a cyanide-sensitive monooxygenase in the 4-demethylation of 4,4-dimethylzymosterol by yeast microsomes. 1981 Biochim. Biophys. Acta pmid:6163470
Maitra US et al. Purification of a terminal oxygenase in demethylation of C-30 of lanosterol. 1982 Biochem. Biophys. Res. Commun. pmid:6816234
Maitra US et al. Biosynthetic preparation of labeled 4,4-dimethylzymosterol. 1989 Mar-May Steroids pmid:2799859
Baudry K et al. The effect of the erg26-1 mutation on the regulation of lipid metabolism in Saccharomyces cerevisiae. 2001 J. Biol. Chem. pmid:11279045
Swain E et al. Sterol-dependent regulation of sphingolipid metabolism in Saccharomyces cerevisiae. 2002 J. Biol. Chem. pmid:12006573
Nose H et al. PF1163A, a novel antifungal agent, inhibit ergosterol biosynthesis at C-4 sterol methyl oxidase. 2002 J. Antibiot. pmid:12546418
Darnet S and Rahier A Enzymological properties of sterol-C4-methyl-oxidase of yeast sterol biosynthesis. 2003 Biochim. Biophys. Acta pmid:12880870
Mo C et al. In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity. 2003 Biochim. Biophys. Acta pmid:12842197
Mo C et al. The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). 2004 Biochim. Biophys. Acta pmid:15522820