4,4-dimethylzymosterol

4,4-dimethylzymosterol is a lipid of Sterol Lipids (ST) class. The involved functions are known as Synthesis, Anabolism, sphingolipid biosynthesis, Permissiveness, Biological Function and ergosterol biosynthesis. 4,4-dimethylzymosterol often locates in Microsomes, Protoplasm and Face. The associated genes with 4,4-dimethylzymosterol are DLC1 gene. The related lipids are Sterols, zymosterol, Cholestenones, coprostanone and Sphingolipids.

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Introduction

To understand associated biological information of 4,4-dimethylzymosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4,4-dimethylzymosterol?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 4,4-dimethylzymosterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with 4,4-dimethylzymosterol?

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What functions are associated with 4,4-dimethylzymosterol?


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What lipids are associated with 4,4-dimethylzymosterol?

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What genes are associated with 4,4-dimethylzymosterol?

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What common seen animal models are associated with 4,4-dimethylzymosterol?

There are no associated biomedical information in the current reference collection.

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All references with 4,4-dimethylzymosterol

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Authors Title Published Journal PubMed Link
Sugai M et al. Characterization of sterol lipids in Kluyveromyces lactis strain M-16 accumulating a high amount of steryl glucoside. 2009 J Oleo Sci pmid:19145063
Gleason JE et al. Analysis of hypoxia and hypoxia-like states through metabolite profiling. 2011 PLoS ONE pmid:21931840
Sukhanova A et al. Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation. 2013 Cancer Discov pmid:23125191
Maitra US et al. Biosynthetic preparation of labeled 4,4-dimethylzymosterol. 1989 Mar-May Steroids pmid:2799859
Aoyama Y et al. Involvement of cytochrome b5 and a cyanide-sensitive monooxygenase in the 4-demethylation of 4,4-dimethylzymosterol by yeast microsomes. 1981 Biochim. Biophys. Acta pmid:6163470
Maitra US et al. Purification of a terminal oxygenase in demethylation of C-30 of lanosterol. 1982 Biochem. Biophys. Res. Commun. pmid:6816234