20-hydroxycholesterol

20-hydroxycholesterol is a lipid of Sterol Lipids (ST) class. The related lipids are 20-hydroxycholesterol, Steroids and Pregnenes.

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Introduction

To understand associated biological information of 20-hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 20-hydroxycholesterol?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 20-hydroxycholesterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 20-hydroxycholesterol?

There are no associated biomedical information in the current reference collection.

What functions are associated with 20-hydroxycholesterol?

There are no associated biomedical information in the current reference collection.

What lipids are associated with 20-hydroxycholesterol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 20-hydroxycholesterol?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 20-hydroxycholesterol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 20-hydroxycholesterol

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Authors Title Published Journal PubMed Link
Berretta A et al. Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis. 2016 Sci Rep pmid:26902390
Bhatia C et al. Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships. 2015 Chem. Biol. Interact. pmid:25526675
Nachtergaele S et al. Oxysterols are allosteric activators of the oncoprotein Smoothened. 2012 Nat. Chem. Biol. pmid:22231273
Jadhav U and Jameson JL Steroidogenic factor-1 (SF-1)-driven differentiation of murine embryonic stem (ES) cells into a gonadal lineage. 2011 Endocrinology pmid:21610156
Son KM et al. Enhancement of the ALP activity of C3H10T1/2 cells by the combination of an oxysterol and apatite. 2010 Biomed Mater pmid:20683129
Kim WK et al. Osteogenic oxysterol, 20(S)-hydroxycholesterol, induces notch target gene expression in bone marrow stromal cells. 2010 J. Bone Miner. Res. pmid:19839776
Kim WK et al. 20(S)-hydroxycholesterol inhibits PPARgamma expression and adipogenic differentiation of bone marrow stromal cells through a hedgehog-dependent mechanism. 2007 J. Bone Miner. Res. pmid:17638575
Rohatgi R et al. Patched1 regulates hedgehog signaling at the primary cilium. 2007 Science pmid:17641202
Shouhed D et al. Osteogenic oxysterols inhibit the adverse effects of oxidative stress on osteogenic differentiation of marrow stromal cells. 2005 J. Cell. Biochem. pmid:15880703
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Zhao D et al. Novel signaling stimulated by arsenite increases cholesterol metabolism through increases in unphosphorylated steroidogenic acute regulatory (StAR) protein. 2005 Mol. Cell. Endocrinol. pmid:15713539
Matyash V et al. Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16. 2004 PLoS Biol. pmid:15383841
Abidi P et al. Suppression of steroidogenesis and activator protein-1 transcription factor activity in rat adrenals by vitamin E deficiency-induced chronic oxidative stress. 2004 J. Nutr. Biochem. pmid:15068814
Tuckey RC et al. Molten globule structure and steroidogenic activity of N-218 MLN64 in human placental mitochondria. 2004 Endocrinology pmid:14715710
Lin YY et al. The detection of 20S-hydroxycholesterol in extracts of rat brains and human placenta by a gas chromatograph/mass spectrometry technique. 2003 J. Steroid Biochem. Mol. Biol. pmid:12798357
Xia H and Redman CM Oxysterols suppress constitutive fibrinogen expression. 2003 Thromb. Haemost. pmid:12876624
Laffitte BA et al. LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11149950
Tomer S et al. Nonionic micellar liquid chromatography coupled to immobilized enzyme reactors. 2001 J Chromatogr A pmid:11510562
Yang SC and Chen KH The oxidation of cholesterol in the yolk of selective traditional Chinese egg products. 2001 Poult. Sci. pmid:11261569
Norlin M et al. Oxysterol 7 alpha-hydroxylase activity by cholesterol 7 alpha-hydroxylase (CYP7A). 2000 J. Biol. Chem. pmid:10882719