| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Suang S et al. | Larval diapause termination in the bamboo borer, Omphisa fuscidentalis. | 2017 | PLoS ONE | pmid:28369111 |
| Mhashilkar AS et al. | Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections. | 2016 | PLoS Negl Trop Dis | pmid:27300294 |
| Tsukagoshi Y et al. | Functional characterization of CYP71D443, a cytochrome P450 catalyzing C-22 hydroxylation in the 20-hydroxyecdysone biosynthesis of Ajuga hairy roots. | 2016 | Phytochemistry | pmid:27017303 |
| Wu YS et al. | Steroid hormone "cortisone" and "20-hydroxyecdysone" involved in the non-specific immune responses of white shrimp (Litopenaeus vannamei). | 2016 | Fish Shellfish Immunol. | pmid:27403594 |
| Liu H et al. | Synergistic protective effect of paeoniflorin and β-ecdysterone against rotenone-induced neurotoxicity in PC12 cells. | 2016 | Apoptosis | pmid:27688248 |
| Childs LM et al. | Disrupting Mosquito Reproduction and Parasite Development for Malaria Control. | 2016 | PLoS Pathog. | pmid:27977810 |
| Liu Y et al. | The Sublethal Effects of β-Ecdysterone, a Highly Active Compound from Achyranthes bidentata Blume, on Grape Phylloxera, Daktulosphaira vitifoliae Fitch. | 2016 | PLoS ONE | pmid:27824901 |
| Thorat L et al. | Desiccation stress induces developmental heterochrony in Drosophila melanogaster. | 2016 | J. Biosci. | pmid:27581925 |
| Wang D et al. | The Steroid Hormone 20-Hydroxyecdysone Promotes the Cytoplasmic Localization of Yorkie to Suppress Cell Proliferation and Induce Apoptosis. | 2016 | J. Biol. Chem. | pmid:27551043 |
| Gokhale RH et al. | Intra-organ growth coordination in Drosophila is mediated by systemic ecdysone signaling. | 2016 | Dev. Biol. | pmid:27452628 |
| Li K et al. | 20-Hydroxyecdysone (20E) Primary Response Gene E75 Isoforms Mediate Steroidogenesis Autoregulation and Regulate Developmental Timing in Bombyx. | 2016 | J. Biol. Chem. | pmid:27365399 |
| Chiang YN et al. | Steroid Hormone Signaling Is Essential for Pheromone Production and Oenocyte Survival. | 2016 | PLoS Genet. | pmid:27333054 |
| Akagi K et al. | A biological timer in the fat body comprising Blimp-1, βFtz-f1 and Shade regulates pupation timing in Drosophila melanogaster. | 2016 | Development | pmid:27226323 |
| Jing YP et al. | The Steroid Hormone 20-Hydroxyecdysone Enhances Gene Transcription through the cAMP Response Element-binding Protein (CREB) Signaling Pathway. | 2016 | J. Biol. Chem. | pmid:27129227 |
| Gong J et al. | The retinoid X receptor from mud crab: new insights into its roles in ovarian development and related signaling pathway. | 2016 | Sci Rep | pmid:27009370 |
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| Mhashilkar AS et al. | Phenotypic and molecular analysis of the effect of 20-hydroxyecdysone on the human filarial parasite Brugia malayi. | 2016 | Int. J. Parasitol. | pmid:26896576 |
| Cai MJ et al. | 20-Hydroxyecdysone activates Forkhead box O to promote proteolysis during Helicoverpa armigera molting. | 2016 | Development | pmid:26893349 |
| Xie K et al. | BmATG5 and BmATG6 mediate apoptosis following autophagy induced by 20-hydroxyecdysone or starvation. | 2016 | Autophagy | pmid:26727186 |
| Kayukawa T et al. | Krüppel Homolog 1 Inhibits Insect Metamorphosis via Direct Transcriptional Repression of Broad-Complex, a Pupal Specifier Gene. | 2016 | J. Biol. Chem. | pmid:26518872 |
| Enya S et al. | The silkworm glutathione S-transferase gene noppera-bo is required for ecdysteroid biosynthesis and larval development. | 2015 | Insect Biochem. Mol. Biol. | pmid:25881968 |
| Fu KY et al. | Knockdown of a nutrient amino acid transporter gene LdNAT1 reduces free neutral amino acid contents and impairs Leptinotarsa decemlineata pupation. | 2015 | Sci Rep | pmid:26657797 |
| Mazina MY et al. | Early-late genes of the ecdysone cascade as models for transcriptional studies. | 2015 | Cell Cycle | pmid:26506480 |
| Liu X et al. | Multicopper oxidase-1 is required for iron homeostasis in Malpighian tubules of Helicoverpa armigera. | 2015 | Sci Rep | pmid:26437857 |
| Monteiro A et al. | Differential Expression of Ecdysone Receptor Leads to Variation in Phenotypic Plasticity across Serial Homologs. | 2015 | PLoS Genet. | pmid:26405828 |
| Liu X et al. | 20-Hydroxyecdysone (20E) Primary Response Gene E93 Modulates 20E Signaling to Promote Bombyx Larval-Pupal Metamorphosis. | 2015 | J. Biol. Chem. | pmid:26378227 |
| Roy S et al. | Regulation of Gene Expression Patterns in Mosquito Reproduction. | 2015 | PLoS Genet. | pmid:26274815 |
| Dong DJ et al. | The Steroid Hormone 20-Hydroxyecdysone Up-regulates Ste-20 Family Serine/Threonine Kinase Hippo to Induce Programmed Cell Death. | 2015 | J. Biol. Chem. | pmid:26272745 |
| Dzitko K et al. | Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells. | 2015 | Parasit Vectors | pmid:26272689 |
| Areiza M et al. | 20-Hydroxyecdysone stimulation of juvenile hormone biosynthesis by the mosquito corpora allata. | 2015 | Insect Biochem. Mol. Biol. | pmid:26255691 |
| Li K et al. | Bombyx E75 isoforms display stage- and tissue-specific responses to 20-hydroxyecdysone. | 2015 | Sci Rep | pmid:26166384 |
| Liu Y et al. | Identification and Characterization of a Novel Microvitellogenin from the Chinese Oak Silkworm Antheraea pernyi. | 2015 | PLoS ONE | pmid:26126120 |
| Ueno T et al. | Changes in the Gene Expression Profiles of the Hypopharyngeal Gland of Worker Honeybees in Association with Worker Behavior and Hormonal Factors. | 2015 | PLoS ONE | pmid:26083737 |
| Dai W et al. | β-Ecdysone Augments Peak Bone Mass in Mice of Both Sexes. | 2015 | Clin. Orthop. Relat. Res. | pmid:25822452 |
| Skała E et al. | Establishment of hairy root cultures of Rhaponticum carthamoides (Willd.) Iljin for the production of biomass and caffeic acid derivatives. | 2015 | Biomed Res Int | pmid:25811023 |
| Eichner C et al. | Characterization of a novel RXR receptor in the salmon louse (Lepeophtheirus salmonis, Copepoda) regulating growth and female reproduction. | 2015 | BMC Genomics | pmid:25765704 |
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| Bozzolan F et al. | Synaptotagmin I, a molecular target for steroid hormone signaling controlling the maturation of sexual behavior in an insect. | 2015 | FEBS J. | pmid:25683246 |
| Jing YP et al. | The steroid hormone 20-hydroxyecdysone via nongenomic pathway activates Ca2+/calmodulin-dependent protein kinase II to regulate gene expression. | 2015 | J. Biol. Chem. | pmid:25670853 |
| Sheu SY et al. | Arthropod steroid hormone (20-Hydroxyecdysone) suppresses IL-1β-induced catabolic gene expression in cartilage. | 2015 | BMC Complement Altern Med | pmid:25617057 |
| Dai W et al. | Prevention of glucocorticoid induced bone changes with beta-ecdysone. | 2015 | Bone | pmid:25585248 |
| Cheng C et al. | The POU factor ventral veins lacking/Drifter directs the timing of metamorphosis through ecdysteroid and juvenile hormone signaling. | 2014 | PLoS Genet. | pmid:24945490 |
| Graf BL et al. | Quinoa seeds leach phytoecdysteroids and other compounds with anti-diabetic properties. | 2014 | Food Chem | pmid:24912714 |
| Kozłowska M et al. | Calponin-like Chd64 is partly disordered. | 2014 | PLoS ONE | pmid:24805353 |
| Tan KL et al. | Ecdysone mediates the development of immunity in the Drosophila embryo. | 2014 | Curr. Biol. | pmid:24794300 |
| Provost-Javier KN and Rasgon JL | 20-hydroxyecdysone mediates non-canonical regulation of mosquito vitellogenins through alternative splicing. | 2014 | Insect Mol. Biol. | pmid:24720618 |
| Wassim NM et al. | Isolation of stem cells from the mid gut epithelium of Culex pipiens mosquitoes (Diptera: Culicidae). | 2014 | J Egypt Soc Parasitol | pmid:24961007 |
| Wan PJ et al. | The putative Halloween gene phantom involved in ecdysteroidogenesis in the white-backed planthopper Sogatella furcifera. | 2014 | Gene | pmid:25017052 |
| Xu H et al. | Identification of a functional element in the promoter of the silkworm (Bombyx mori) fat body-specific gene Bmlp3. | 2014 | Gene | pmid:24853203 |
| Liu H et al. | E93 predominantly transduces 20-hydroxyecdysone signaling to induce autophagy and caspase activity in Drosophila fat body. | 2014 | Insect Biochem. Mol. Biol. | pmid:24316411 |
| Sharipov RR et al. | [Induction of oxidative stress in heart mitochondria in brain focal ischemia-reperfusion and protective effect of ecdysterone]. | 2014 | Fiziol Zh | pmid:25095666 |
| Zhang K et al. | Characterization and identification of the integrin family in silkworm, Bombyx mori. | 2014 | Gene | pmid:25064490 |
| Domanitskaya E et al. | Phantom, a cytochrome P450 enzyme essential for ecdysone biosynthesis, plays a critical role in the control of border cell migration in Drosophila. | 2014 | Dev. Biol. | pmid:24373956 |
| Wang HB et al. | Stage-specific activation of the E74B promoter by low ecdysone concentrations in the wing disc of Bombyx mori. | 2014 | Gene | pmid:24393712 |
| Tasdemir-Yilmaz OE and Freeman MR | Astrocytes engage unique molecular programs to engulf pruned neuronal debris from distinct subsets of neurons. | 2014 | Genes Dev. | pmid:24361692 |
| Cai MJ et al. | G-protein-coupled receptor participates in 20-hydroxyecdysone signaling on the plasma membrane. | 2014 | Cell Commun. Signal | pmid:24507557 |
| Liu W et al. | In a nongenomic action, steroid hormone 20-hydroxyecdysone induces phosphorylation of cyclin-dependent kinase 10 to promote gene transcription. | 2014 | Endocrinology | pmid:24517229 |
| Liu W et al. | Phospholipase Cγ1 connects the cell membrane pathway to the nuclear receptor pathway in insect steroid hormone signaling. | 2014 | J. Biol. Chem. | pmid:24692553 |
| Ono H | Ecdysone differentially regulates metamorphic timing relative to 20-hydroxyecdysone by antagonizing juvenile hormone in Drosophila melanogaster. | 2014 | Dev. Biol. | pmid:24727669 |
| Niitsu S et al. | Ecdysteroid-induced programmed cell death is essential for sex-specific wing degeneration of the wingless-female winter moth. | 2014 | PLoS ONE | pmid:24558499 |
| Li Y et al. | Steroid signaling promotes stem cell maintenance in the Drosophila testis. | 2014 | Dev. Biol. | pmid:25093968 |
| Gabrieli P et al. | Sexual transfer of the steroid hormone 20E induces the postmating switch in Anopheles gambiae. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25368171 |
| Li Z et al. | CYP18A1 regulates tissue-specific steroid hormone inactivation in Bombyx mori. | 2014 | Insect Biochem. Mol. Biol. | pmid:25173591 |
| Zhao B et al. | Regulation of the gut-specific carboxypeptidase: a study using the binary Gal4/UAS system in the mosquito Aedes aegypti. | 2014 | Insect Biochem. Mol. Biol. | pmid:25152428 |
| Cai MJ et al. | Juvenile hormone prevents 20-hydroxyecdysone-induced metamorphosis by regulating the phosphorylation of a newly identified broad protein. | 2014 | J. Biol. Chem. | pmid:25096576 |
| Adonyeva NV et al. | Insulin affects dopamine metabolism in Drosophila females under normal and stress conditions. | 2013 Jan-Feb | Dokl. Biochem. Biophys. | pmid:23478985 |
| Chaitanya RK et al. | Effect of juvenile hormone analog, methoprene on H-fibroin regulation during the last instar larval development of Corcyra cephalonica. | 2013 | Gen. Comp. Endocrinol. | pmid:22929589 |
| Cheng DM et al. | Continuous infusion of 20-hydroxyecdysone increased mass of triceps brachii in C57BL/6 mice. | 2013 | Phytother Res | pmid:22495969 |
| Dong DJ et al. | Steroid hormone 20-hydroxyecdysone regulation of the very-high-density lipoprotein (VHDL) receptor phosphorylation for VHDL uptake. | 2013 | Insect Biochem. Mol. Biol. | pmid:23416133 |
| Qian Z et al. | cDNA cloning and expression analysis of myostatin/GDF11 in shrimp, Litopenaeus vannamei. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23402749 |
| Chen J et al. | Conserved microRNAs miR-8-5p and miR-2a-3p modulate chitin biosynthesis in response to 20-hydroxyecdysone signaling in the brown planthopper, Nilaparvata lugens. | 2013 | Insect Biochem. Mol. Biol. | pmid:23796434 |
| Hossain MS et al. | 20-Hydroxyecdysone-induced transcriptional activity of FoxO upregulates brummer and acid lipase-1 and promotes lipolysis in Bombyx fat body. | 2013 | Insect Biochem. Mol. Biol. | pmid:23811219 |
| Liu W et al. | The hormone-dependent function of Hsp90 in the crosstalk between 20-hydroxyecdysone and juvenile hormone signaling pathways in insects is determined by differential phosphorylation and protein interactions. | 2013 | Biochim. Biophys. Acta | pmid:23850472 |
| Sun R et al. | Characterization of the response to ecdysteroid of a novel cuticle protein R&R gene in the honey bee, Apis cerana cerana. | 2013 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:23856183 |
| Geddes LH et al. | Steroid hormone (20-hydroxyecdysone) modulates the acquisition of aversive olfactory memories in pollen forager honeybees. | 2013 | Learn. Mem. | pmid:23858051 |
| Tarhan L et al. | The glutathione-related detoxication responses to juvenile and ecdysone hormones in Galleria mellonella. | 2013 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:23684736 |
| Liu CY et al. | Upregulation of the expression of prodeath serine/threonine protein kinase for programmed cell death by steroid hormone 20-hydroxyecdysone. | 2013 | Apoptosis | pmid:23203537 |
| Eresen Yazıcıoğlu C et al. | ACVR1 gene mutations in four Turkish patients diagnosed as fibrodysplasia ossificans progressiva. | 2013 | Gene | pmid:23260810 |
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20-hydroxyecdysone
20-hydroxyecdysone is a lipid of Sterol Lipids (ST) class. 20-hydroxyecdysone is associated with abnormalities such as Congenital Abnormality, Obesity, Diabetes, Varicosity and Gilbert Disease. The involved functions are known as Binding (Molecular Function), Anabolism, Embryonic Development, Signal Transduction and Transcriptional Activation. 20-hydroxyecdysone often locates in Epidermis, Epithelium, Body tissue, Head and Blood. The associated genes with 20-hydroxyecdysone are GBGT1 gene, Homologous Gene, Genome, MMRN1 gene and Orthologous Gene. The related lipids are Steroids, muristerone, makisterone, Sterols and Liposomes.
Cross Reference
Introduction
To understand associated biological information of 20-hydroxyecdysone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 20-hydroxyecdysone?
20-hydroxyecdysone is suspected in Congenital Abnormality, Obesity, Diabetes, Varicosity, Gilbert Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with 20-hydroxyecdysone
Lipid pathways are not clear in current pathway databases. We organized associated pathways with 20-hydroxyecdysone through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 20-hydroxyecdysone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 20-hydroxyecdysone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 20-hydroxyecdysone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 20-hydroxyecdysone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 20-hydroxyecdysone?
There are no associated biomedical information in the current reference collection.