| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Mhashilkar AS et al. | Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections. | 2016 | PLoS Negl Trop Dis | pmid:27300294 |
| Tsukagoshi Y et al. | Functional characterization of CYP71D443, a cytochrome P450 catalyzing C-22 hydroxylation in the 20-hydroxyecdysone biosynthesis of Ajuga hairy roots. | 2016 | Phytochemistry | pmid:27017303 |
| Wu YS et al. | Steroid hormone "cortisone" and "20-hydroxyecdysone" involved in the non-specific immune responses of white shrimp (Litopenaeus vannamei). | 2016 | Fish Shellfish Immunol. | pmid:27403594 |
| Liu H et al. | Synergistic protective effect of paeoniflorin and β-ecdysterone against rotenone-induced neurotoxicity in PC12 cells. | 2016 | Apoptosis | pmid:27688248 |
| Childs LM et al. | Disrupting Mosquito Reproduction and Parasite Development for Malaria Control. | 2016 | PLoS Pathog. | pmid:27977810 |
| Liu Y et al. | The Sublethal Effects of β-Ecdysterone, a Highly Active Compound from Achyranthes bidentata Blume, on Grape Phylloxera, Daktulosphaira vitifoliae Fitch. | 2016 | PLoS ONE | pmid:27824901 |
| Thorat L et al. | Desiccation stress induces developmental heterochrony in Drosophila melanogaster. | 2016 | J. Biosci. | pmid:27581925 |
| Wang D et al. | The Steroid Hormone 20-Hydroxyecdysone Promotes the Cytoplasmic Localization of Yorkie to Suppress Cell Proliferation and Induce Apoptosis. | 2016 | J. Biol. Chem. | pmid:27551043 |
| Gokhale RH et al. | Intra-organ growth coordination in Drosophila is mediated by systemic ecdysone signaling. | 2016 | Dev. Biol. | pmid:27452628 |
| Li K et al. | 20-Hydroxyecdysone (20E) Primary Response Gene E75 Isoforms Mediate Steroidogenesis Autoregulation and Regulate Developmental Timing in Bombyx. | 2016 | J. Biol. Chem. | pmid:27365399 |
| Chiang YN et al. | Steroid Hormone Signaling Is Essential for Pheromone Production and Oenocyte Survival. | 2016 | PLoS Genet. | pmid:27333054 |
| Akagi K et al. | A biological timer in the fat body comprising Blimp-1, βFtz-f1 and Shade regulates pupation timing in Drosophila melanogaster. | 2016 | Development | pmid:27226323 |
| Jing YP et al. | The Steroid Hormone 20-Hydroxyecdysone Enhances Gene Transcription through the cAMP Response Element-binding Protein (CREB) Signaling Pathway. | 2016 | J. Biol. Chem. | pmid:27129227 |
| Gong J et al. | The retinoid X receptor from mud crab: new insights into its roles in ovarian development and related signaling pathway. | 2016 | Sci Rep | pmid:27009370 |
| Sang W et al. | UVB Radiation Delays Tribolium castaneum Metamorphosis by Influencing Ecdysteroid Metabolism. | 2016 | PLoS ONE | pmid:26986217 |
| Mhashilkar AS et al. | Phenotypic and molecular analysis of the effect of 20-hydroxyecdysone on the human filarial parasite Brugia malayi. | 2016 | Int. J. Parasitol. | pmid:26896576 |
| Cai MJ et al. | 20-Hydroxyecdysone activates Forkhead box O to promote proteolysis during Helicoverpa armigera molting. | 2016 | Development | pmid:26893349 |
| Xie K et al. | BmATG5 and BmATG6 mediate apoptosis following autophagy induced by 20-hydroxyecdysone or starvation. | 2016 | Autophagy | pmid:26727186 |
| Kayukawa T et al. | Krüppel Homolog 1 Inhibits Insect Metamorphosis via Direct Transcriptional Repression of Broad-Complex, a Pupal Specifier Gene. | 2016 | J. Biol. Chem. | pmid:26518872 |
| Enya S et al. | The silkworm glutathione S-transferase gene noppera-bo is required for ecdysteroid biosynthesis and larval development. | 2015 | Insect Biochem. Mol. Biol. | pmid:25881968 |
| Fu KY et al. | Knockdown of a nutrient amino acid transporter gene LdNAT1 reduces free neutral amino acid contents and impairs Leptinotarsa decemlineata pupation. | 2015 | Sci Rep | pmid:26657797 |
| Mazina MY et al. | Early-late genes of the ecdysone cascade as models for transcriptional studies. | 2015 | Cell Cycle | pmid:26506480 |
| Liu X et al. | Multicopper oxidase-1 is required for iron homeostasis in Malpighian tubules of Helicoverpa armigera. | 2015 | Sci Rep | pmid:26437857 |
| Monteiro A et al. | Differential Expression of Ecdysone Receptor Leads to Variation in Phenotypic Plasticity across Serial Homologs. | 2015 | PLoS Genet. | pmid:26405828 |
| Liu X et al. | 20-Hydroxyecdysone (20E) Primary Response Gene E93 Modulates 20E Signaling to Promote Bombyx Larval-Pupal Metamorphosis. | 2015 | J. Biol. Chem. | pmid:26378227 |
| Roy S et al. | Regulation of Gene Expression Patterns in Mosquito Reproduction. | 2015 | PLoS Genet. | pmid:26274815 |
| Dong DJ et al. | The Steroid Hormone 20-Hydroxyecdysone Up-regulates Ste-20 Family Serine/Threonine Kinase Hippo to Induce Programmed Cell Death. | 2015 | J. Biol. Chem. | pmid:26272745 |
| Dzitko K et al. | Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells. | 2015 | Parasit Vectors | pmid:26272689 |
| Areiza M et al. | 20-Hydroxyecdysone stimulation of juvenile hormone biosynthesis by the mosquito corpora allata. | 2015 | Insect Biochem. Mol. Biol. | pmid:26255691 |
| Li K et al. | Bombyx E75 isoforms display stage- and tissue-specific responses to 20-hydroxyecdysone. | 2015 | Sci Rep | pmid:26166384 |
| Liu Y et al. | Identification and Characterization of a Novel Microvitellogenin from the Chinese Oak Silkworm Antheraea pernyi. | 2015 | PLoS ONE | pmid:26126120 |
| Ueno T et al. | Changes in the Gene Expression Profiles of the Hypopharyngeal Gland of Worker Honeybees in Association with Worker Behavior and Hormonal Factors. | 2015 | PLoS ONE | pmid:26083737 |
| Dai W et al. | β-Ecdysone Augments Peak Bone Mass in Mice of Both Sexes. | 2015 | Clin. Orthop. Relat. Res. | pmid:25822452 |
| Skała E et al. | Establishment of hairy root cultures of Rhaponticum carthamoides (Willd.) Iljin for the production of biomass and caffeic acid derivatives. | 2015 | Biomed Res Int | pmid:25811023 |
| Eichner C et al. | Characterization of a novel RXR receptor in the salmon louse (Lepeophtheirus salmonis, Copepoda) regulating growth and female reproduction. | 2015 | BMC Genomics | pmid:25765704 |
| Mitchell SN et al. | Mosquito biology. Evolution of sexual traits influencing vectorial capacity in anopheline mosquitoes. | 2015 | Science | pmid:25722409 |
| Bozzolan F et al. | Synaptotagmin I, a molecular target for steroid hormone signaling controlling the maturation of sexual behavior in an insect. | 2015 | FEBS J. | pmid:25683246 |
| Jing YP et al. | The steroid hormone 20-hydroxyecdysone via nongenomic pathway activates Ca2+/calmodulin-dependent protein kinase II to regulate gene expression. | 2015 | J. Biol. Chem. | pmid:25670853 |
| Sheu SY et al. | Arthropod steroid hormone (20-Hydroxyecdysone) suppresses IL-1β-induced catabolic gene expression in cartilage. | 2015 | BMC Complement Altern Med | pmid:25617057 |
| Dai W et al. | Prevention of glucocorticoid induced bone changes with beta-ecdysone. | 2015 | Bone | pmid:25585248 |
| Wassim NM et al. | Isolation of stem cells from the mid gut epithelium of Culex pipiens mosquitoes (Diptera: Culicidae). | 2014 | J Egypt Soc Parasitol | pmid:24961007 |
| Wan PJ et al. | The putative Halloween gene phantom involved in ecdysteroidogenesis in the white-backed planthopper Sogatella furcifera. | 2014 | Gene | pmid:25017052 |
| Xu H et al. | Identification of a functional element in the promoter of the silkworm (Bombyx mori) fat body-specific gene Bmlp3. | 2014 | Gene | pmid:24853203 |
| Liu H et al. | E93 predominantly transduces 20-hydroxyecdysone signaling to induce autophagy and caspase activity in Drosophila fat body. | 2014 | Insect Biochem. Mol. Biol. | pmid:24316411 |
| Sharipov RR et al. | [Induction of oxidative stress in heart mitochondria in brain focal ischemia-reperfusion and protective effect of ecdysterone]. | 2014 | Fiziol Zh | pmid:25095666 |
| Zhang K et al. | Characterization and identification of the integrin family in silkworm, Bombyx mori. | 2014 | Gene | pmid:25064490 |
| Domanitskaya E et al. | Phantom, a cytochrome P450 enzyme essential for ecdysone biosynthesis, plays a critical role in the control of border cell migration in Drosophila. | 2014 | Dev. Biol. | pmid:24373956 |
| Wang HB et al. | Stage-specific activation of the E74B promoter by low ecdysone concentrations in the wing disc of Bombyx mori. | 2014 | Gene | pmid:24393712 |
| Tasdemir-Yilmaz OE and Freeman MR | Astrocytes engage unique molecular programs to engulf pruned neuronal debris from distinct subsets of neurons. | 2014 | Genes Dev. | pmid:24361692 |
20-hydroxyecdysone
20-hydroxyecdysone is a lipid of Sterol Lipids (ST) class. 20-hydroxyecdysone is associated with abnormalities such as Congenital Abnormality, Obesity, Diabetes, Varicosity and Gilbert Disease. The involved functions are known as Binding (Molecular Function), Anabolism, Embryonic Development, Signal Transduction and Transcriptional Activation. 20-hydroxyecdysone often locates in Epidermis, Epithelium, Body tissue, Head and Blood. The associated genes with 20-hydroxyecdysone are GBGT1 gene, Homologous Gene, Genome, MMRN1 gene and Orthologous Gene. The related lipids are Steroids, muristerone, makisterone, Sterols and Liposomes.
Cross Reference
Introduction
To understand associated biological information of 20-hydroxyecdysone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 20-hydroxyecdysone?
20-hydroxyecdysone is suspected in Congenital Abnormality, Obesity, Diabetes, Varicosity, Gilbert Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with 20-hydroxyecdysone
Lipid pathways are not clear in current pathway databases. We organized associated pathways with 20-hydroxyecdysone through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 20-hydroxyecdysone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 20-hydroxyecdysone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 20-hydroxyecdysone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 20-hydroxyecdysone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 20-hydroxyecdysone?
There are no associated biomedical information in the current reference collection.