| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Praggastis SA and Thummel CS | Right time, right place: the temporal regulation of developmental gene expression. | 2017 | Genes Dev. | pmid:28566535 |
| Uyehara CM et al. | Hormone-dependent control of developmental timing through regulation of chromatin accessibility. | 2017 | Genes Dev. | pmid:28536147 |
| Wang P et al. | Transcriptome analysis of the epidermis of the purple quail-like (q-lp) mutant of silkworm, Bombyx mori. | 2017 | PLoS ONE | pmid:28414820 |
| Ohhara Y et al. | Nutrient-Dependent Endocycling in Steroidogenic Tissue Dictates Timing of Metamorphosis in Drosophila melanogaster. | 2017 | PLoS Genet. | pmid:28121986 |
| Suang S et al. | Larval diapause termination in the bamboo borer, Omphisa fuscidentalis. | 2017 | PLoS ONE | pmid:28369111 |
| Mhashilkar AS et al. | Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections. | 2016 | PLoS Negl Trop Dis | pmid:27300294 |
| Chauhan P et al. | Transcriptome profiling in the damselfly Ischnura elegans identifies genes with sex-biased expression. | 2016 | BMC Genomics | pmid:27905879 |
| Xiong XP et al. | miR-34 Modulates Innate Immunity and Ecdysone Signaling in Drosophila. | 2016 | PLoS Pathog. | pmid:27893816 |
| Hitrik A et al. | Combgap Promotes Ovarian Niche Development and Chromatin Association of EcR-Binding Regions in BR-C. | 2016 | PLoS Genet. | pmid:27846223 |
| Goncu E et al. | Developmental Expression of Ecdysone-Related Genes Associated With Metamorphic Changes During Midgut Remodeling of Silkworm Bombyx mori (Lepidoptera:Bombycidae). | 2016 | J. Insect Sci. | pmid:27620558 |
| Jaszczak JS et al. | Growth Coordination During Drosophila melanogaster Imaginal Disc Regeneration Is Mediated by Signaling Through the Relaxin Receptor Lgr3 in the Prothoracic Gland. | 2016 | Genetics | pmid:27558136 |
| Wang J et al. | De novo Transcriptome Analysis of Chinese Citrus Fly, Bactrocera minax (Diptera: Tephritidae), by High-Throughput Illumina Sequencing. | 2016 | PLoS ONE | pmid:27331903 |
| Danielsen ET et al. | A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing. | 2016 | Dev. Cell | pmid:27326933 |
| Bhogal B et al. | Nanos-mediated repression of hid protects larval sensory neurons after a global switch in sensitivity to apoptotic signals. | 2016 | Development | pmid:27256879 |
| Masuoka Y and Maekawa K | Ecdysone signaling regulates soldier-specific cuticular pigmentation in the termite Zootermopsis nevadensis. | 2016 | FEBS Lett. | pmid:27208413 |
| Jia D et al. | The Ecdysone and Notch Pathways Synergistically Regulate Cut at the Dorsal-Ventral Boundary in Drosophila Wing Discs. | 2016 | J Genet Genomics | pmid:27117286 |
| Sun W et al. | Ecdysone Titer Determined by 3DE-3β-Reductase Enhances the Immune Response in the Silkworm. | 2016 | J. Immunol. | pmid:26773159 |
| Stoiber M et al. | Diverse Hormone Response Networks in 41 Independent Drosophila Cell Lines. | 2016 | G3 (Bethesda) | pmid:26772746 |
| Valzania L et al. | Drosophila 4EHP is essential for the larval-pupal transition and required in the prothoracic gland for ecdysone biosynthesis. | 2016 | Dev. Biol. | pmid:26721418 |
| Mendes CC and Mirth CK | Stage-Specific Plasticity in Ovary Size Is Regulated by Insulin/Insulin-Like Growth Factor and Ecdysone Signaling in Drosophila. | 2016 | Genetics | pmid:26715667 |
| Mansilla A et al. | Ligand-independent requirements of steroid receptors EcR and USP for cell survival. | 2016 | Cell Death Differ. | pmid:26250909 |
| Gokhale RH et al. | Intra-organ growth coordination in Drosophila is mediated by systemic ecdysone signaling. | 2016 | Dev. Biol. | pmid:27452628 |
| Pahi Z et al. | dTAF10- and dTAF10b-Containing Complexes Are Required for Ecdysone-Driven Larval-Pupal Morphogenesis in Drosophila melanogaster. | 2015 | PLoS ONE | pmid:26556600 |
| Yamanaka N et al. | Vesicle-Mediated Steroid Hormone Secretion in Drosophila melanogaster. | 2015 | Cell | pmid:26544939 |
| Lucas KJ et al. | Mosquito-specific microRNA-1890 targets the juvenile hormone-regulated serine protease JHA15 in the female mosquito gut. | 2015 | RNA Biol | pmid:26488481 |
| Skinner A et al. | Trithorax regulates systemic signaling during Drosophila imaginal disc regeneration. | 2015 | Development | pmid:26487779 |
| Planelló R et al. | Ecdysone-Related Biomarkers of Toxicity in the Model Organism Chironomus riparius: Stage and Sex-Dependent Variations in Gene Expression Profiles. | 2015 | PLoS ONE | pmid:26448051 |
| Lavrynenko O et al. | The ecdysteroidome of Drosophila: influence of diet and development. | 2015 | Development | pmid:26395481 |
| Nicolson S et al. | Ecdysone-mediated programmed cell death in Drosophila. | 2015 | Int. J. Dev. Biol. | pmid:26374522 |
| Van Bortle K et al. | Integrated tRNA, transcript, and protein profiles in response to steroid hormone signaling. | 2015 | RNA | pmid:26289344 |
| Meng M et al. | The homeodomain transcription factors antennapedia and POU-M2 regulate the transcription of the steroidogenic enzyme gene Phantom in the silkworm. | 2015 | J. Biol. Chem. | pmid:26253172 |
| Herboso L et al. | Ecdysone promotes growth of imaginal discs through the regulation of Thor in D. melanogaster. | 2015 | Sci Rep | pmid:26198204 |
| Jaszczak JS et al. | Nitric Oxide Synthase Regulates Growth Coordination During Drosophila melanogaster Imaginal Disc Regeneration. | 2015 | Genetics | pmid:26081194 |
| Skalska L et al. | Chromatin signatures at Notch-regulated enhancers reveal large-scale changes in H3K56ac upon activation. | 2015 | EMBO J. | pmid:26069324 |
| Borsos BN et al. | Acetylations of Ftz-F1 and histone H4K5 are required for the fine-tuning of ecdysone biosynthesis during Drosophila metamorphosis. | 2015 | Dev. Biol. | pmid:25959239 |
| Sieber MH and Spradling AC | Steroid Signaling Establishes a Female Metabolic State and Regulates SREBP to Control Oocyte Lipid Accumulation. | 2015 | Curr. Biol. | pmid:25802149 |
| Wang D et al. | G-protein-coupled receptor controls steroid hormone signaling in cell membrane. | 2015 | Sci Rep | pmid:25728569 |
| Qian W et al. | Ecdysone receptor (EcR) is involved in the transcription of cell cycle genes in the silkworm. | 2015 | Int J Mol Sci | pmid:25654229 |
| Hickner PV et al. | Whole transcriptome responses among females of the filariasis and arbovirus vector mosquito Culex pipiens implicate TGF-β signaling and chromatin modification as key drivers of diapause induction. | 2015 | Funct. Integr. Genomics | pmid:25634120 |
| Lengil T et al. | Activin signaling balances proliferation and differentiation of ovarian niche precursors and enables adjustment of niche numbers. | 2015 | Development | pmid:25633355 |
| Ohhara Y et al. | Autocrine regulation of ecdysone synthesis by β3-octopamine receptor in the prothoracic gland is essential for Drosophila metamorphosis. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25605909 |
| Gautam NK et al. | Ecdysone regulates morphogenesis and function of Malpighian tubules in Drosophila melanogaster through EcR-B2 isoform. | 2015 | Dev. Biol. | pmid:25476260 |
| Dzitko K et al. | Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells. | 2015 | Parasit Vectors | pmid:26272689 |
| Ueno T et al. | Changes in the Gene Expression Profiles of the Hypopharyngeal Gland of Worker Honeybees in Association with Worker Behavior and Hormonal Factors. | 2015 | PLoS ONE | pmid:26083737 |
| Nijhout HF et al. | The developmental control of size in insects. | 2014 Jan-Feb | Wiley Interdiscip Rev Dev Biol | pmid:24902837 |
| Koyama T et al. | Nutritional control of body size through FoxO-Ultraspiracle mediated ecdysone biosynthesis. | 2014 | Elife | pmid:25421296 |
| Huang YC et al. | The COP9 signalosome converts temporal hormone signaling to spatial restriction on neural competence. | 2014 | PLoS Genet. | pmid:25393278 |
| Daniels EV et al. | Extensive transcriptional response associated with seasonal plasticity of butterfly wing patterns. | 2014 | Mol. Ecol. | pmid:25369871 |
| Liu Y et al. | Comparative characterization of two intracellular Ca²âº-release channels from the red flour beetle, Tribolium castaneum. | 2014 | Sci Rep | pmid:25330781 |
| Sandoval H et al. | Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production. | 2014 | Elife | pmid:25313867 |
| Dennis SR et al. | Endocrine regulation of predator-induced phenotypic plasticity. | 2014 | Oecologia | pmid:25284611 |
| Parvy JP et al. | Forward and feedback regulation of cyclic steroid production in Drosophila melanogaster. | 2014 | Development | pmid:25252945 |
| Buttitta L and Lee CY | Ch-ch-changes: hormones link stem cell differentiation with metabolic flux. | 2014 | Cell Stem Cell | pmid:25192460 |
| Bernardo TJ et al. | A view through a chromatin loop: insights into the ecdysone activation of early genes in Drosophila. | 2014 | Nucleic Acids Res. | pmid:25143532 |
| Homem CCF et al. | Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells. | 2014 | Cell | pmid:25126791 |
| Iga M et al. | Pigment dispersing factor regulates ecdysone biosynthesis via bombyx neuropeptide G protein coupled receptor-B2 in the prothoracic glands of Bombyx mori. | 2014 | PLoS ONE | pmid:25072638 |
| Tianpei X et al. | Optimized scorpion polypeptide LMX: a pest control protein effective against rice leaf folder. | 2014 | PLoS ONE | pmid:24964088 |
| Danielsen ET et al. | Transcriptional control of steroid biosynthesis genes in the Drosophila prothoracic gland by ventral veins lacking and knirps. | 2014 | PLoS Genet. | pmid:24945799 |
| Oliveira MM et al. | Coordination of wing and whole-body development at developmental milestones ensures robustness against environmental and physiological perturbations. | 2014 | PLoS Genet. | pmid:24945255 |
| Gündner AL et al. | The PIKE homolog Centaurin gamma regulates developmental timing in Drosophila. | 2014 | PLoS ONE | pmid:24845618 |
| Claudius AK et al. | Unexpected role of the steroid-deficiency protein ecdysoneless in pre-mRNA splicing. | 2014 | PLoS Genet. | pmid:24722212 |
| Reis M et al. | Genes belonging to the insulin and ecdysone signaling pathways can contribute to developmental time, lifespan and abdominal size variation in Drosophila americana. | 2014 | PLoS ONE | pmid:24489769 |
| Deng H | Multiple roles of Nrf2-Keap1 signaling: regulation of development and xenobiotic response using distinct mechanisms. | 2014 | Fly (Austin) | pmid:24406335 |
| Domanitskaya E et al. | Phantom, a cytochrome P450 enzyme essential for ecdysone biosynthesis, plays a critical role in the control of border cell migration in Drosophila. | 2014 | Dev. Biol. | pmid:24373956 |
| Wang HB et al. | Stage-specific activation of the E74B promoter by low ecdysone concentrations in the wing disc of Bombyx mori. | 2014 | Gene | pmid:24393712 |
| Ono H | Ecdysone differentially regulates metamorphic timing relative to 20-hydroxyecdysone by antagonizing juvenile hormone in Drosophila melanogaster. | 2014 | Dev. Biol. | pmid:24727669 |
| Yang C et al. | The Broad Complex isoform 2 (BrC-Z2) transcriptional factor plays a critical role in vitellogenin transcription in the silkworm Bombyx mori. | 2014 | Biochim. Biophys. Acta | pmid:24861733 |
| Liu Z et al. | Two small heat shock protein genes in Apis cerana cerana: characterization, regulation, and developmental expression. | 2014 | Gene | pmid:24835315 |
| Ozáez I et al. | The UV filter benzophenone 3 (BP-3) activates hormonal genes mimicking the action of ecdysone and alters embryo development in the insect Chironomus riparius (Diptera). | 2014 | Environ. Pollut. | pmid:24878782 |
| Kayukawa T et al. | Hormonal regulation and developmental role of Krüppel homolog 1, a repressor of metamorphosis, in the silkworm Bombyx mori. | 2014 | Dev. Biol. | pmid:24508345 |
| Neuman SD et al. | INO80-dependent regression of ecdysone-induced transcriptional responses regulates developmental timing in Drosophila. | 2014 | Dev. Biol. | pmid:24468295 |
| Shaw WR et al. | Mating activates the heme peroxidase HPX15 in the sperm storage organ to ensure fertility in Anopheles gambiae. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24711401 |
| Shlyueva D et al. | Hormone-responsive enhancer-activity maps reveal predictive motifs, indirect repression, and targeting of closed chromatin. | 2014 | Mol. Cell | pmid:24685159 |
| Cho KH et al. | Secretory competence in a gateway endocrine cell conferred by the nuclear receptor βFTZ-F1 enables stage-specific ecdysone responses throughout development in Drosophila. | 2014 | Dev. Biol. | pmid:24247008 |
| Kang Y and Bashirullah A | A steroid-controlled global switch in sensitivity to apoptosis during Drosophila development. | 2014 | Dev. Biol. | pmid:24333635 |
| Santhanam A et al. | Ecdysone-induced receptor tyrosine phosphatase PTP52F regulates Drosophila midgut histolysis by enhancement of autophagy and apoptosis. | 2014 | Mol. Cell. Biol. | pmid:24550005 |
| Ihry RJ and Bashirullah A | Genetic control of specificity to steroid-triggered responses in Drosophila. | 2014 | Genetics | pmid:24374353 |
| Rumpf S et al. | Drosophila Valosin-Containing Protein is required for dendrite pruning through a regulatory role in mRNA metabolism. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24799714 |
| Mirth CK et al. | Juvenile hormone regulates body size and perturbs insulin signaling in Drosophila. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24778227 |
| Shyamal S et al. | The Y-organ secretory activity fluctuates in relation to seasons of molt and reproduction in the brachyuran crab, Metopograpsus messor (Grapsidae): Ultrastructural and immunohistochemical study. | 2014 | Gen. Comp. Endocrinol. | pmid:24291010 |
| Veverytsa L and Allan DW | Subtype-specific neuronal remodeling during Drosophila metamorphosis. | 2013 Apr-Jun | Fly (Austin) | pmid:23579264 |
| De Loof A et al. | The mode of action of juvenile hormone and ecdysone: towards an epi-endocrinological paradigm? | 2013 | Gen. Comp. Endocrinol. | pmid:23454668 |
| Zhang Y et al. | A regulatory pathway, ecdysone-transcription factor relish-cathepsin L, is involved in insect fat body dissociation. | 2013 | PLoS Genet. | pmid:23459255 |
| Boulan L et al. | bantam miRNA promotes systemic growth by connecting insulin signaling and ecdysone production. | 2013 | Curr. Biol. | pmid:23477723 |
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Ecdysone
Ecdysone is a lipid of Sterol Lipids (ST) class. Ecdysone is associated with abnormalities such as Lafora Disease, Congenital Abnormality, Infection, protrusion and Morphologically altered structure. The involved functions are known as Cardiac Arrest, Transcription, Genetic, receptor function, Stimulus and Signal Transduction. Ecdysone often locates in Body tissue, Chromosomes, Polytene Chromosome, Epidermis and Muscle. The associated genes with Ecdysone are FATE1 gene, LGALS4 gene, Transgenes, LacZ Genes and C10orf27 gene. The related lipids are Steroids, FuGene, muristerone, N,N-dimethyl-N-hexadecyl-1-octadecylammonium chloride and 7-dehydrocholesterol. The related experimental models are Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Ecdysone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ecdysone?
Ecdysone is suspected in Congenital Abnormality, Cyst, Gilbert Disease, Morphologically altered structure, Bacterial Infections, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with Ecdysone
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ecdysone through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ecdysone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Ecdysone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ecdysone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ecdysone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ecdysone?
Tissue Model
Tissue Model are used in the study 'Molecular mechanisms of developmental timing in C. elegans and Drosophila.' (Thummel CS, 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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