Ecdysone

Ecdysone is a lipid of Sterol Lipids (ST) class. Ecdysone is associated with abnormalities such as Lafora Disease, Congenital Abnormality, Infection, protrusion and Morphologically altered structure. The involved functions are known as Cardiac Arrest, Transcription, Genetic, receptor function, Stimulus and Signal Transduction. Ecdysone often locates in Body tissue, Chromosomes, Polytene Chromosome, Epidermis and Muscle. The associated genes with Ecdysone are FATE1 gene, LGALS4 gene, Transgenes, LacZ Genes and C10orf27 gene. The related lipids are Steroids, FuGene, muristerone, N,N-dimethyl-N-hexadecyl-1-octadecylammonium chloride and 7-dehydrocholesterol. The related experimental models are Tissue Model.

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Introduction

To understand associated biological information of Ecdysone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ecdysone?

Ecdysone is suspected in Congenital Abnormality, Cyst, Gilbert Disease, Morphologically altered structure, Bacterial Infections, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Ecdysone

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ecdysone through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ecdysone?

Related references are published most in these journals:

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What functions are associated with Ecdysone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ecdysone?

Related references are published most in these journals:

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What genes are associated with Ecdysone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ecdysone?

Tissue Model

Tissue Model are used in the study 'Molecular mechanisms of developmental timing in C. elegans and Drosophila.' (Thummel CS, 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Ecdysone

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Authors Title Published Journal PubMed Link
Praggastis SA and Thummel CS Right time, right place: the temporal regulation of developmental gene expression. 2017 Genes Dev. pmid:28566535
Uyehara CM et al. Hormone-dependent control of developmental timing through regulation of chromatin accessibility. 2017 Genes Dev. pmid:28536147
Wang P et al. Transcriptome analysis of the epidermis of the purple quail-like (q-lp) mutant of silkworm, Bombyx mori. 2017 PLoS ONE pmid:28414820
Ohhara Y et al. Nutrient-Dependent Endocycling in Steroidogenic Tissue Dictates Timing of Metamorphosis in Drosophila melanogaster. 2017 PLoS Genet. pmid:28121986
Suang S et al. Larval diapause termination in the bamboo borer, Omphisa fuscidentalis. 2017 PLoS ONE pmid:28369111
Mhashilkar AS et al. Identification of Ecdysone Hormone Receptor Agonists as a Therapeutic Approach for Treating Filarial Infections. 2016 PLoS Negl Trop Dis pmid:27300294
Chauhan P et al. Transcriptome profiling in the damselfly Ischnura elegans identifies genes with sex-biased expression. 2016 BMC Genomics pmid:27905879
Xiong XP et al. miR-34 Modulates Innate Immunity and Ecdysone Signaling in Drosophila. 2016 PLoS Pathog. pmid:27893816
Hitrik A et al. Combgap Promotes Ovarian Niche Development and Chromatin Association of EcR-Binding Regions in BR-C. 2016 PLoS Genet. pmid:27846223
Goncu E et al. Developmental Expression of Ecdysone-Related Genes Associated With Metamorphic Changes During Midgut Remodeling of Silkworm Bombyx mori (Lepidoptera:Bombycidae). 2016 J. Insect Sci. pmid:27620558
Jaszczak JS et al. Growth Coordination During Drosophila melanogaster Imaginal Disc Regeneration Is Mediated by Signaling Through the Relaxin Receptor Lgr3 in the Prothoracic Gland. 2016 Genetics pmid:27558136
Wang J et al. De novo Transcriptome Analysis of Chinese Citrus Fly, Bactrocera minax (Diptera: Tephritidae), by High-Throughput Illumina Sequencing. 2016 PLoS ONE pmid:27331903
Danielsen ET et al. A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing. 2016 Dev. Cell pmid:27326933
Bhogal B et al. Nanos-mediated repression of hid protects larval sensory neurons after a global switch in sensitivity to apoptotic signals. 2016 Development pmid:27256879
Masuoka Y and Maekawa K Ecdysone signaling regulates soldier-specific cuticular pigmentation in the termite Zootermopsis nevadensis. 2016 FEBS Lett. pmid:27208413
Jia D et al. The Ecdysone and Notch Pathways Synergistically Regulate Cut at the Dorsal-Ventral Boundary in Drosophila Wing Discs. 2016 J Genet Genomics pmid:27117286
Sun W et al. Ecdysone Titer Determined by 3DE-3β-Reductase Enhances the Immune Response in the Silkworm. 2016 J. Immunol. pmid:26773159
Stoiber M et al. Diverse Hormone Response Networks in 41 Independent Drosophila Cell Lines. 2016 G3 (Bethesda) pmid:26772746
Valzania L et al. Drosophila 4EHP is essential for the larval-pupal transition and required in the prothoracic gland for ecdysone biosynthesis. 2016 Dev. Biol. pmid:26721418
Mendes CC and Mirth CK Stage-Specific Plasticity in Ovary Size Is Regulated by Insulin/Insulin-Like Growth Factor and Ecdysone Signaling in Drosophila. 2016 Genetics pmid:26715667
Mansilla A et al. Ligand-independent requirements of steroid receptors EcR and USP for cell survival. 2016 Cell Death Differ. pmid:26250909
Gokhale RH et al. Intra-organ growth coordination in Drosophila is mediated by systemic ecdysone signaling. 2016 Dev. Biol. pmid:27452628
Pahi Z et al. dTAF10- and dTAF10b-Containing Complexes Are Required for Ecdysone-Driven Larval-Pupal Morphogenesis in Drosophila melanogaster. 2015 PLoS ONE pmid:26556600
Yamanaka N et al. Vesicle-Mediated Steroid Hormone Secretion in Drosophila melanogaster. 2015 Cell pmid:26544939
Lucas KJ et al. Mosquito-specific microRNA-1890 targets the juvenile hormone-regulated serine protease JHA15 in the female mosquito gut. 2015 RNA Biol pmid:26488481
Skinner A et al. Trithorax regulates systemic signaling during Drosophila imaginal disc regeneration. 2015 Development pmid:26487779
Planelló R et al. Ecdysone-Related Biomarkers of Toxicity in the Model Organism Chironomus riparius: Stage and Sex-Dependent Variations in Gene Expression Profiles. 2015 PLoS ONE pmid:26448051
Lavrynenko O et al. The ecdysteroidome of Drosophila: influence of diet and development. 2015 Development pmid:26395481
Nicolson S et al. Ecdysone-mediated programmed cell death in Drosophila. 2015 Int. J. Dev. Biol. pmid:26374522
Van Bortle K et al. Integrated tRNA, transcript, and protein profiles in response to steroid hormone signaling. 2015 RNA pmid:26289344
Meng M et al. The homeodomain transcription factors antennapedia and POU-M2 regulate the transcription of the steroidogenic enzyme gene Phantom in the silkworm. 2015 J. Biol. Chem. pmid:26253172
Herboso L et al. Ecdysone promotes growth of imaginal discs through the regulation of Thor in D. melanogaster. 2015 Sci Rep pmid:26198204
Jaszczak JS et al. Nitric Oxide Synthase Regulates Growth Coordination During Drosophila melanogaster Imaginal Disc Regeneration. 2015 Genetics pmid:26081194
Skalska L et al. Chromatin signatures at Notch-regulated enhancers reveal large-scale changes in H3K56ac upon activation. 2015 EMBO J. pmid:26069324
Borsos BN et al. Acetylations of Ftz-F1 and histone H4K5 are required for the fine-tuning of ecdysone biosynthesis during Drosophila metamorphosis. 2015 Dev. Biol. pmid:25959239
Sieber MH and Spradling AC Steroid Signaling Establishes a Female Metabolic State and Regulates SREBP to Control Oocyte Lipid Accumulation. 2015 Curr. Biol. pmid:25802149
Wang D et al. G-protein-coupled receptor controls steroid hormone signaling in cell membrane. 2015 Sci Rep pmid:25728569
Qian W et al. Ecdysone receptor (EcR) is involved in the transcription of cell cycle genes in the silkworm. 2015 Int J Mol Sci pmid:25654229
Hickner PV et al. Whole transcriptome responses among females of the filariasis and arbovirus vector mosquito Culex pipiens implicate TGF-β signaling and chromatin modification as key drivers of diapause induction. 2015 Funct. Integr. Genomics pmid:25634120
Lengil T et al. Activin signaling balances proliferation and differentiation of ovarian niche precursors and enables adjustment of niche numbers. 2015 Development pmid:25633355
Ohhara Y et al. Autocrine regulation of ecdysone synthesis by β3-octopamine receptor in the prothoracic gland is essential for Drosophila metamorphosis. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:25605909
Gautam NK et al. Ecdysone regulates morphogenesis and function of Malpighian tubules in Drosophila melanogaster through EcR-B2 isoform. 2015 Dev. Biol. pmid:25476260
Dzitko K et al. Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells. 2015 Parasit Vectors pmid:26272689
Ueno T et al. Changes in the Gene Expression Profiles of the Hypopharyngeal Gland of Worker Honeybees in Association with Worker Behavior and Hormonal Factors. 2015 PLoS ONE pmid:26083737
Nijhout HF et al. The developmental control of size in insects. 2014 Jan-Feb Wiley Interdiscip Rev Dev Biol pmid:24902837
Bernardo TJ et al. A view through a chromatin loop: insights into the ecdysone activation of early genes in Drosophila. 2014 Nucleic Acids Res. pmid:25143532
Homem CCF et al. Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells. 2014 Cell pmid:25126791
Iga M et al. Pigment dispersing factor regulates ecdysone biosynthesis via bombyx neuropeptide G protein coupled receptor-B2 in the prothoracic glands of Bombyx mori. 2014 PLoS ONE pmid:25072638
Tianpei X et al. Optimized scorpion polypeptide LMX: a pest control protein effective against rice leaf folder. 2014 PLoS ONE pmid:24964088
Wang HB et al. Stage-specific activation of the E74B promoter by low ecdysone concentrations in the wing disc of Bombyx mori. 2014 Gene pmid:24393712