20a-hydroxy cholesterol

20a-hydroxy cholesterol is a lipid of Sterol Lipids (ST) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 103 references associated with 20a-hydroxy cholesterol in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Berretta A et al. Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis. 2016 Sci Rep pmid:26902390
Nachtergaele S et al. Oxysterols are allosteric activators of the oncoprotein Smoothened. 2012 Nat. Chem. Biol. pmid:22231273
Son KM et al. Enhancement of the ALP activity of C3H10T1/2 cells by the combination of an oxysterol and apatite. 2010 Biomed Mater pmid:20683129
Kim WK et al. Osteogenic oxysterol, 20(S)-hydroxycholesterol, induces notch target gene expression in bone marrow stromal cells. 2010 J. Bone Miner. Res. pmid:19839776
Kim WK et al. 20(S)-hydroxycholesterol inhibits PPARgamma expression and adipogenic differentiation of bone marrow stromal cells through a hedgehog-dependent mechanism. 2007 J. Bone Miner. Res. pmid:17638575
Rohatgi R et al. Patched1 regulates hedgehog signaling at the primary cilium. 2007 Science pmid:17641202
Shouhed D et al. Osteogenic oxysterols inhibit the adverse effects of oxidative stress on osteogenic differentiation of marrow stromal cells. 2005 J. Cell. Biochem. pmid:15880703
Lin YY et al. The detection of 20S-hydroxycholesterol in extracts of rat brains and human placenta by a gas chromatograph/mass spectrometry technique. 2003 J. Steroid Biochem. Mol. Biol. pmid:12798357
Xia H and Redman CM Oxysterols suppress constitutive fibrinogen expression. 2003 Thromb. Haemost. pmid:12876624
Laffitte BA et al. LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11149950
Matthys L et al. Differential sensitivity to ACTH, but not stress, in two sources of outbred Sprague-Dawley rats. 1998 Neuroendocrinology pmid:9662720
Arai M and Widmaier EP Steroidogenesis in isolated adrenocortical cells during development in rats. 1993 Mol. Cell. Endocrinol. pmid:8386118
Liu KZ et al. Oxidative status of lipoproteins in coronary disease patients. 1992 Am. Heart J. pmid:1736561
Laskey JW and Phelps PV Effect of cadmium and other metal cations on in vitro Leydig cell testosterone production. 1991 Toxicol. Appl. Pharmacol. pmid:1850171
Azhar S et al. Okadaic acid interferes with lipoprotein-supported corticosterone production in adrenal cells. 1991 Biochem. Biophys. Res. Commun. pmid:1654900
Guo H et al. Interleukin-2 is a potent inhibitor of Leydig cell steroidogenesis. 1990 Endocrinology pmid:2167211
Wing TY et al. Restoration effects of exogenous luteinizing hormone on the testicular steroidogenesis and Leydig cell ultrastructure. 1985 Endocrinology pmid:4042963
Rooney MW et al. Oxygenated cholesterols synergistically immobilize acyl chains and enhance protein helical structure in human erythrocyte membranes. 1985 Biochim. Biophys. Acta pmid:4052416
Klimek J et al. The relationship between NADPH-dependent lipid peroxidation and degradation of cytochrome P-450 in adrenal cortex mitochondria. 1983 Biochem. Biophys. Res. Commun. pmid:6838538
Spangrude GJ et al. Inhibitory effects of various oxygenated sterols on the differentiation and function of tumor-specific cytotoxic T lymphocytes. 1982 Transplantation pmid:6979815
Shimizu T et al. Resonance Raman spectra of bovine adrenal cytochrome P-450SCC. 1981 Biochim. Biophys. Acta pmid:7295776
Duncan JL and Buckingham L Resistance to streptolysin O in mammalian cells treated with oxygenated derivatives of cholesterol. Cholesterol content of resistant cells and recovery of streptolysin O sensitivity. 1980 Biochim. Biophys. Acta pmid:7459354
HALL PF and KORITZ SB INHIBITION OF THE BIOSYNTHESIS OF PREGNENOLONE BY 20-ALPHA-HYDROXYCHOLESTEROL. 1964 Biochim. Biophys. Acta pmid:14251332
SHIMIZU K et al. Isocaproic acid, a metabolite of 20 alpha-hydroxycholesterol. 1960 J. Biol. Chem. pmid:14446007
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