(2e,4e)-deca-2,4-dienal

(2e,4e)-deca-2,4-dienal is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 362 references associated with (2e,4e)-deca-2,4-dienal in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (2e,4e)-deca-2,4-dienal

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (2e,4e)-deca-2,4-dienal

MeSH term MeSH ID Detail
Congenital Abnormalities D000013 11 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
Total 5

NCBI Entrez Crosslinks

All references with (2e,4e)-deca-2,4-dienal

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Authors Title Published Journal PubMed Link
Sabharwal T et al. Defense related decadienal elicits membrane lipid remodeling in the diatom Phaeodactylum tricornutum. 2017 PLoS ONE pmid:28582415
Zhang GH et al. A study revealing the key aroma compounds of steamed bread made by Chinese traditional sourdough. 2016 Oct. J Zhejiang Univ Sci B pmid:27704748
Abdo N et al. Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study. 2015 Environ. Health Perspect. pmid:25622337
Wolfram S et al. A Metabolic Probe-Enabled Strategy Reveals Uptake and Protein Targets of Polyunsaturated Aldehydes in the Diatom Phaeodactylum tricornutum. 2015 PLoS ONE pmid:26496085
Lettieri A et al. Ciona intestinalis as a marine model system to study some key developmental genes targeted by the diatom-derived aldehyde decadienal. 2015 Mar Drugs pmid:25789602
Castellano I et al. The diatom-derived aldehyde decadienal affects life cycle transition in the ascidian Ciona intestinalis through nitric oxide/ERK signalling. 2015 Open Biol pmid:25788553
Park CW et al. The effect of feed solids concentration and inlet temperature on the flavor of spray dried whey protein concentrate. 2014 J. Food Sci. pmid:24329978
Gołębiowski M et al. Antimicrobial activity of untypical lipid compounds in the cuticular and internal lipids of four fly species. 2014 J. Appl. Microbiol. pmid:24238211
Sansone C et al. Diatom-derived polyunsaturated aldehydes activate cell death in human cancer cell lines but not normal cells. 2014 PLoS ONE pmid:24992192
Kâ S et al. Impact of the diatom-derived polyunsaturated aldehyde 2-trans,4-trans decadienal on the feeding, survivorship and reproductive success of the calanoid copepod Temora stylifera. 2014 Mar. Environ. Res. pmid:23992954
Caboni P et al. Potent nematicidal activity of phthalaldehyde, salicylaldehyde, and cinnamic aldehyde against Meloidogyne incognita. 2013 J. Agric. Food Chem. pmid:23379671
Bchini R et al. Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition. 2013 Chem. Biol. Interact. pmid:23220587
Marrone V et al. Defensome against toxic diatom aldehydes in the sea urchin Paracentrotus lividus. 2012 PLoS ONE pmid:22363721
Caboni P et al. Nematicidal activity of (E,E)-2,4-decadienal and (E)-2-decenal from Ailanthus altissima against Meloidogyne javanica. 2012 J. Agric. Food Chem. pmid:22224661
Zhang Y et al. Off-flavor related volatiles in soymilk as affected by soybean variety, grinding, and heat-processing methods. 2012 J. Agric. Food Chem. pmid:22812487
Farag MA and Wessjohann LA Volatiles profiling in medicinal licorice roots using steam distillation and solid-phase microextraction (SPME) coupled to chemometrics. 2012 J. Food Sci. pmid:23126623
Kocadağlı T et al. In depth study of acrylamide formation in coffee during roasting: role of sucrose decomposition and lipid oxidation. 2012 Food Funct pmid:22796869
Chan PC NTP toxicity studies of toxicity studies of 2,4-decadienal (CAS No. 25152-84-5) administered by gavage to F344/N Rats and B6C3F1 mice. 2011 Toxic Rep Ser pmid:21445102
Christlbauer M and Schieberle P Evaluation of the key aroma compounds in beef and pork vegetable gravies a la chef by stable isotope dilution assays and aroma recombination experiments. 2011 J. Agric. Food Chem. pmid:22077665
Zhu X et al. Mass spectrometric evidence for the existence of distinct modifications of different proteins by 2(E),4(E)-decadienal. 2010 Chem. Res. Toxicol. pmid:20070074
Harispe L et al. Biochemical analysis of a recombinant glutathione transferase from the cestode Echinococcus granulosus. 2010 Acta Trop. pmid:20034460
Wang CK et al. Pulmonary changes induced by trans,trans-2,4-decadienal, a component of cooking oil fumes. 2010 Eur. Respir. J. pmid:19797125
Zamora R et al. Conversion of 3-aminopropionamide and 3-alkylaminopropionamides into acrylamide in model systems. 2009 Mol Nutr Food Res pmid:19746374
Endo S et al. Characterization of a rat NADPH-dependent aldo-keto reductase (AKR1B13) induced by oxidative stress. 2009 Chem. Biol. Interact. pmid:18845131
Lin PP et al. Proteomic analysis of proteins associated with tt-DDE induced toxicity in BEAS-2B cells. 2008 Biochem. Biophys. Res. Commun. pmid:18796293
Liu ZX and Liu ZX [Chemical constituents from the seed of Chimonanthus praecox extracted by supercritical carbon dioxide]. 2008 Zhong Yao Cai pmid:18973012
Ribalet F et al. Differential effect of three polyunsaturated aldehydes on marine bacterial isolates. 2008 Aquat. Toxicol. pmid:18093670
Chang YC and Lin P Trans, trans-2,4-decadienal induced cell proliferation via p27 pathway in human bronchial epithelial cells. 2008 Toxicol. Appl. Pharmacol. pmid:18187174
Morita M and Tokita M Hydroxy radical, hexanal, and decadienal generation by autocatalysts in autoxidation of linoleate alone and with eleostearate. 2008 Lipids pmid:18493810
Gallardo E et al. Influence of lipids in the generation of phenylacetaldehyde in wort-related model systems. 2008 J. Agric. Food Chem. pmid:18386901
Vardi A et al. A diatom gene regulating nitric-oxide signaling and susceptibility to diatom-derived aldehydes. 2008 Curr. Biol. pmid:18538570
Buttino I et al. Aldehyde-encapsulating liposomes impair marine grazer survivorship. 2008 J. Exp. Biol. pmid:18424676
Zamora R et al. Strecker degradation of phenylalanine initiated by 2,4-decadienal or methyl 13-oxooctadeca-9,11-dienoate in model systems. 2007 J. Agric. Food Chem. pmid:17300152
Ribalet F et al. Growth inhibition of cultured marine phytoplankton by toxic algal-derived polyunsaturated aldehydes. 2007 Aquat. Toxicol. pmid:17942163
Chen W et al. Identification of volatile degradants in formulations containing sesame oil using SPME/GC/MS. 2007 J Pharm Biomed Anal pmid:17412547
Hung HS et al. Association of cooking oil fumes exposure with lung cancer: involvement of inhibitor of apoptosis proteins in cell survival and proliferation in vitro. 2007 Mutat. Res. pmid:17229588
Yuan Q et al. Chemical nature of stochastic generation of protein-based carbonyls: metal-catalyzed oxidation versus modification by products of lipid oxidation. 2007 Chem. Res. Toxicol. pmid:17226935
Sigolo CA et al. Covalent modification of cytochrome c exposed to trans,trans-2,4-decadienal. 2007 Chem. Res. Toxicol. pmid:17658762
Vardi A et al. A stress surveillance system based on calcium and nitric oxide in marine diatoms. 2006 PLoS Biol. pmid:16475869
Caldwell GS et al. Exposure to 2,4-decadienal negatively impacts upon marine invertebrate larval fitness. 2005 Mar. Environ. Res. pmid:15603766
Chang LW et al. Trans, trans-2,4-decadienal, a product found in cooking oil fumes, induces cell proliferation and cytokine production due to reactive oxygen species in human bronchial epithelial cells. 2005 Toxicol. Sci. pmid:16014734
Shirokova E et al. Identification of specific ligands for orphan olfactory receptors. G protein-dependent agonism and antagonism of odorants. 2005 J. Biol. Chem. pmid:15598656
Wu SC and Yen GC Effects of cooking oil fumes on the genotoxicity and oxidative stress in human lung carcinoma (A-549) cells. 2004 Toxicol In Vitro pmid:15251174
Loureiro AP et al. Structural characterization of diastereoisomeric ethano adducts derived from the reaction of 2'-deoxyguanosine with trans,trans-2,4-decadienal. 2004 Chem. Res. Toxicol. pmid:15144221
Hansen E et al. Isolation and characterisation of a cytotoxic polyunsaturated aldehyde from the marine phytoplankter Phaeocystis pouchetii (Hariot) Lagerheim. 2004 Toxicology pmid:15147794
Bezman Y et al. Differential effects of tomato (Lycopersicon esculentum mill) matrix on the volatility of important aroma compounds. 2003 J. Agric. Food Chem. pmid:12537448
Niknahad H et al. Modulating carbonyl cytotoxicity in intact rat hepatocytes by inhibiting carbonyl-metabolizing enzymes. I. Aliphatic alkenals. 2003 Chem. Biol. Interact. pmid:12604195
Akakabe Y et al. 2,4-Decadienals are produced via (R)-11-HPITE from arachidonic acid in marine green alga Ulva conglobata. 2003 Bioorg. Med. Chem. pmid:12901905
Cabré A et al. Cytotoxic effects of the lipid peroxidation product 2,4-decadienal in vascular smooth muscle cells. 2003 Atherosclerosis pmid:12921975
Romano G et al. A marine diatom-derived aldehyde induces apoptosis in copepod and sea urchin embryos. 2003 J. Exp. Biol. pmid:12939379