(2e,4e)-deca-2,4-dienal

(2e,4e)-deca-2,4-dienal is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 362 references associated with (2e,4e)-deca-2,4-dienal in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (2e,4e)-deca-2,4-dienal

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (2e,4e)-deca-2,4-dienal

MeSH term MeSH ID Detail
Congenital Abnormalities D000013 11 associated lipids
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Lung Neoplasms D008175 171 associated lipids
Total 5

NCBI Entrez Crosslinks

All references with (2e,4e)-deca-2,4-dienal

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Harispe L et al. Biochemical analysis of a recombinant glutathione transferase from the cestode Echinococcus granulosus. 2010 Acta Trop. pmid:20034460
Caldwell GS et al. Inhibition of embryonic development and fertilization in broadcast spawning marine invertebrates by water soluble diatom extracts and the diatom toxin 2-trans,4-trans decadienal. 2002 Aquat. Toxicol. pmid:12204592
Ribalet F et al. Growth inhibition of cultured marine phytoplankton by toxic algal-derived polyunsaturated aldehydes. 2007 Aquat. Toxicol. pmid:17942163
Ribalet F et al. Differential effect of three polyunsaturated aldehydes on marine bacterial isolates. 2008 Aquat. Toxicol. pmid:18093670
Cabré A et al. Cytotoxic effects of the lipid peroxidation product 2,4-decadienal in vascular smooth muscle cells. 2003 Atherosclerosis pmid:12921975
Girona J et al. 2,4-Decadienal downregulates TNF-alpha gene expression in THP-1 human macrophages. 2001 Atherosclerosis pmid:11500179
Lin PP et al. Proteomic analysis of proteins associated with tt-DDE induced toxicity in BEAS-2B cells. 2008 Biochem. Biophys. Res. Commun. pmid:18796293
Srivastava S et al. Structural and kinetic determinants of aldehyde reduction by aldose reductase. 1999 Biochemistry pmid:9890881
Hasegawa K et al. Characterization of fluorescent products from reaction of methyl linoleate hydroperoxides with adenine in the presence of Fe2+ and ascorbic acid. 1988 Biochim. Biophys. Acta pmid:3167087
Spiteller P et al. Aldehydic lipid peroxidation products derived from linoleic acid. 2001 Biochim. Biophys. Acta pmid:11325611
Akakabe Y et al. 2,4-Decadienals are produced via (R)-11-HPITE from arachidonic acid in marine green alga Ulva conglobata. 2003 Bioorg. Med. Chem. pmid:12901905
Nappez C et al. trans,trans-2,4-decadienal: cytotoxicity and effect on glutathione level in human erythroleukemia (HEL) cells. 1996 Cancer Lett. pmid:8564922
Niknahad H et al. Modulating carbonyl cytotoxicity in intact rat hepatocytes by inhibiting carbonyl-metabolizing enzymes. I. Aliphatic alkenals. 2003 Chem. Biol. Interact. pmid:12604195
Endo S et al. Characterization of a rat NADPH-dependent aldo-keto reductase (AKR1B13) induced by oxidative stress. 2009 Chem. Biol. Interact. pmid:18845131
Bchini R et al. Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition. 2013 Chem. Biol. Interact. pmid:23220587
Carvalho VM et al. Novel 1,N(6)-etheno-2'-deoxyadenosine adducts from lipid peroxidation products. 2000 Chem. Res. Toxicol. pmid:10813657
Loureiro AP et al. trans,trans-2,4-decadienal-induced 1,N(2)-etheno-2'-deoxyguanosine adduct formation. 2000 Chem. Res. Toxicol. pmid:10898592
Carvalho VM et al. Formation of 1,N6-etheno-2'-deoxyadenosine adducts by trans,trans-2, 4-Decadienal. 1998 Chem. Res. Toxicol. pmid:9760278
Loureiro AP et al. Structural characterization of diastereoisomeric ethano adducts derived from the reaction of 2'-deoxyguanosine with trans,trans-2,4-decadienal. 2004 Chem. Res. Toxicol. pmid:15144221
Zhu X et al. Mass spectrometric evidence for the existence of distinct modifications of different proteins by 2(E),4(E)-decadienal. 2010 Chem. Res. Toxicol. pmid:20070074
Yuan Q et al. Chemical nature of stochastic generation of protein-based carbonyls: metal-catalyzed oxidation versus modification by products of lipid oxidation. 2007 Chem. Res. Toxicol. pmid:17226935
Sigolo CA et al. Covalent modification of cytochrome c exposed to trans,trans-2,4-decadienal. 2007 Chem. Res. Toxicol. pmid:17658762
Vardi A et al. A diatom gene regulating nitric-oxide signaling and susceptibility to diatom-derived aldehydes. 2008 Curr. Biol. pmid:18538570
Abdo N et al. Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study. 2015 Environ. Health Perspect. pmid:25622337
Wang CK et al. Pulmonary changes induced by trans,trans-2,4-decadienal, a component of cooking oil fumes. 2010 Eur. Respir. J. pmid:19797125
Kocadağlı T et al. In depth study of acrylamide formation in coffee during roasting: role of sucrose decomposition and lipid oxidation. 2012 Food Funct pmid:22796869
Cadet J et al. Purine DNA adducts of 4,5-dioxovaleric acid and 2,4-decadienal. 1999 IARC Sci. Publ. pmid:10626212
Chen W et al. Identification of volatile degradants in formulations containing sesame oil using SPME/GC/MS. 2007 J Pharm Biomed Anal pmid:17412547
Zhang GH et al. A study revealing the key aroma compounds of steamed bread made by Chinese traditional sourdough. 2016 Oct. J Zhejiang Univ Sci B pmid:27704748
Christlbauer M and Schieberle P Evaluation of the key aroma compounds in beef and pork vegetable gravies a la chef by stable isotope dilution assays and aroma recombination experiments. 2011 J. Agric. Food Chem. pmid:22077665
Zhang Y et al. Off-flavor related volatiles in soymilk as affected by soybean variety, grinding, and heat-processing methods. 2012 J. Agric. Food Chem. pmid:22812487