Cholesterol-5beta-hydroperoxide

Cholesterol-5beta-hydroperoxide is a lipid of Sterol Lipids (ST) class.

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Current reference collection contains 238 references associated with Cholesterol-5beta-hydroperoxide in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Girotti AW and Korytowski W Cholesterol Hydroperoxide Generation, Translocation, and Reductive Turnover in Biological Systems. 2017 Cell Biochem. Biophys. pmid:28434137
van Lier JE et al. Cholesterol hydroperoxides as substrates for cholesterol-metabolizing cytochrome P450 enzymes and alternative sources of 25-hydroxycholesterol and other oxysterols. 2015 Angew. Chem. Int. Ed. Engl. pmid:26230055
Korytowski W et al. Impairment of Macrophage Cholesterol Efflux by Cholesterol Hydroperoxide Trafficking: Implications for Atherogenesis Under Oxidative Stress. 2015 Arterioscler. Thromb. Vasc. Biol. pmid:26315403
Terao J Cholesterol hydroperoxides and their degradation mechanism. 2014 Subcell. Biochem. pmid:24374920
Nakamura T et al. Non-selective distribution of isomeric cholesterol hydroperoxides to microdomains in cell membranes and activation of matrix metalloproteinase activity in a model of dermal cells. 2013 Chem. Phys. Lipids pmid:23751409
Choi SH et al. Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages. 2013 PLoS ONE pmid:24376657
Korytowski W et al. Deleterious cholesterol hydroperoxide trafficking in steroidogenic acute regulatory (StAR) protein-expressing MA-10 Leydig cells: implications for oxidative stress-impaired steroidogenesis. 2013 J. Biol. Chem. pmid:23467407
Ronsein GE et al. DNA strand breaks and base modifications induced by cholesterol hydroperoxides. 2011 Free Radic. Res. pmid:20942561
Uemi M et al. Cholesterol hydroperoxides generate singlet molecular oxygen [O(2) ((1)Δ(g))]: near-IR emission, (18)O-labeled hydroperoxides, and mass spectrometry. 2011 Chem. Res. Toxicol. pmid:21510702
Broniec A et al. Interactions of plasmalogens and their diacyl analogs with singlet oxygen in selected model systems. 2011 Free Radic. Biol. Med. pmid:21236336
Kriska T et al. Sterol carrier protein-2 (SCP-2) involvement in cholesterol hydroperoxide cytotoxicity as revealed by SCP-2 inhibitor effects. 2010 J. Lipid Res. pmid:20656919
Uemi M et al. Generation of cholesterol carboxyaldehyde by the reaction of singlet molecular oxygen [O2 (1Delta(g))] as well as ozone with cholesterol. 2009 Chem. Res. Toxicol. pmid:19358613
Minami Y et al. Peroxidized cholesterol-induced matrix metalloproteinase-9 activation and its suppression by dietary beta-carotene in photoaging of hairless mouse skin. 2009 J. Nutr. Biochem. pmid:18656335
Asano M et al. Lipid hydroperoxides in human plasma after ethanol consumption. 2009 Leg Med (Tokyo) pmid:19261511
Brinkhorst J et al. Hock cleavage of cholesterol 5alpha-hydroperoxide: an ozone-free pathway to the cholesterol ozonolysis products identified in arterial plaque and brain tissue. 2008 J. Am. Chem. Soc. pmid:18722442
Minami Y et al. Combination of TLC blotting and gas chromatography-mass spectrometry for analysis of peroxidized cholesterol. 2007 Lipids pmid:17701239
Kriska T et al. Intracellular dissemination of peroxidative stress. Internalization, transport, and lethal targeting of a cholesterol hydroperoxide species by sterol carrier protein-2-overexpressing hepatoma cells. 2006 J. Biol. Chem. pmid:16772292
Kriska T and Girotti AW A thin layer chromatographic method for determining the enzymatic activity of peroxidases catalyzing the two-electron reduction of lipid hydroperoxides. 2005 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:15899595
Adachi J et al. Alcoholic muscle disease and biomembrane perturbations (review). 2003 J. Nutr. Biochem. pmid:14629892
Suh J et al. Ascorbate does not act as a pro-oxidant towards lipids and proteins in human plasma exposed to redox-active transition metal ions and hydrogen peroxide. 2003 Free Radic. Biol. Med. pmid:12726918
Kanofsky JR et al. Singlet-oxygen generation from A2E. 2003 Photochem. Photobiol. pmid:12685649
Adachi J et al. Consecutive administration of paraquat to rats induces enhanced cholesterol peroxidation and lung injury. 2003 Arch. Toxicol. pmid:12799775
Preedy VR et al. Free radicals in alcoholic myopathy: indices of damage and preventive studies. 2002 Free Radic. Biol. Med. pmid:11937294
Vila A et al. Spontaneous transfer of phospholipid and cholesterol hydroperoxides between cell membranes and low-density lipoprotein: assessment of reaction kinetics and prooxidant effects. 2002 Biochemistry pmid:12427033
Haralampus-Grynaviski N et al. Photogeneration and quenching of reactive oxygen species by urocanic acid. 2002 J. Am. Chem. Soc. pmid:11916432
Hurst R et al. Hyperresistance to cholesterol hydroperoxide-induced peroxidative injury and apoptotic death in a tumor cell line that overexpresses glutathione peroxidase isotype-4. 2001 Free Radic. Biol. Med. pmid:11677038
Tahara S et al. Age-related changes in oxidative damage to lipids and DNA in rat skin. 2001 Mech. Ageing Dev. pmid:11240163
Vila A et al. Spontaneous intermembrane transfer of various cholesterol-derived hydroperoxide species: kinetic studies with model membranes and cells. 2001 Biochemistry pmid:11724586
Vila A et al. Dissemination of peroxidative stress via intermembrane transfer of lipid hydroperoxides: model studies with cholesterol hydroperoxides. 2000 Arch. Biochem. Biophys. pmid:10900151
Adachi J et al. 7alpha- and 7beta-hydroperoxycholest-5-en-3beta-ol in muscle as indices of oxidative stress: response to ethanol dosage in rats. 2000 Alcohol. Clin. Exp. Res. pmid:10832909
Korytowski W et al. Nitric oxide inhibition of free radical-mediated cholesterol peroxidation in liposomal membranes. 2000 Biochemistry pmid:10841773
Korytowski W and Girotti AW Singlet oxygen adducts of cholesterol: photogeneration and reductive turnover in membrane systems. 1999 Photochem. Photobiol. pmid:10546545
Adachi J et al. Cholesterol hydroperoxides in erythrocyte membranes of alcoholic patients. 1999 Alcohol. Clin. Exp. Res. pmid:10235288
Yamazaki S et al. Quantitative determination of cholesterol 5alpha-, 7alpha-, and 7beta-hydroperoxides in rat skin. 1999 Free Radic. Biol. Med. pmid:10443927
Yamazaki S et al. Photogeneration of 3beta-hydroxy-5alpha-cholest-6-ene-5-hydroperoxide in rat skin: evidence for occurrence of singlet oxygen in vivo. 1999 Free Radic. Biol. Med. pmid:10468202
Armstrong D and Browne RW Synthesis of lipid and cholesterol hydroperoxide standards. 1998 Methods Mol. Biol. pmid:9921524
Geiger PG et al. Lipid peroxidation in photodynamically stressed mammalian cells: use of cholesterol hydroperoxides as mechanistic reporters. 1997 Free Radic. Biol. Med. pmid:9165297
Korytowski W et al. Enzymatic reducibility in relation to cytotoxicity for various cholesterol hydroperoxides. 1996 Biochemistry pmid:8679629
Sakurai T et al. Phospholipase A(2) activity in non-glycated and glycated low density lipoproteins. 1996 Biochim. Biophys. Acta pmid:8652655
Tang L et al. Brugia pahangi: the cuticular glutathione peroxidase (gp29) protects heterologous membranes from lipid peroxidation. 1996 Exp. Parasitol. pmid:8631385
Caruso D et al. Identification of 3 beta-hydroxy-5 alpha-cholest-6-ene-5-hydroperoxide in human oxidized LDL. 1996 Chem. Phys. Lipids pmid:8640903
Geiger PG et al. Photodynamically generated 3-beta-hydroxy-5 alpha-cholest-6-ene-5- hydroperoxide: toxic reactivity in membranes and susceptibility to enzymatic detoxification. 1995 Photochem. Photobiol. pmid:8570716
Coffey MD et al. In vitro cell injury by oxidized low density lipoprotein involves lipid hydroperoxide-induced formation of alkoxyl, lipid, and peroxyl radicals. 1995 J. Clin. Invest. pmid:7560078
Sevanian A et al. Analysis of plasma cholesterol oxidation products using gas- and high-performance liquid chromatography/mass spectrometry. 1994 Free Radic. Biol. Med. pmid:7835746
Christison J et al. Human blood cells support the reduction of low-density-lipoprotein-associated cholesteryl ester hydroperoxides by albumin-bound ebselen. 1994 Biochem. J. pmid:7998966
Korytowski W et al. Analysis of cholesterol and phospholipid hydroperoxides by high-performance liquid chromatography with mercury drop electrochemical detection. 1993 Anal. Biochem. pmid:8238862
Maiorino M et al. Antioxidant effect of Ebselen (PZ 51): peroxidase mimetic activity on phospholipid and cholesterol hydroperoxides vs free radical scavenger activity. 1992 Arch. Biochem. Biophys. pmid:1586168
Meyer BU et al. Peroxide-dependent amino acid oxidation and chemiluminescence catalysed by magnesium-pyridoxal phosphate-glutamate complex. 1992 Biochem. Pharmacol. pmid:1510700
Tipton CL et al. Isolation and characterization of calmodulin-inactivating cholesterol hydroperoxides. 1991 J. Lipid Res. pmid:1753210
Korytowski W et al. Chromatographic separation and electrochemical determination of cholesterol hydroperoxides generated by photodynamic action. 1991 Anal. Biochem. pmid:1952058

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