18:2 Cholesteryl ester

18:2 cholesteryl ester is a lipid of Sterol Lipids (ST) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 342 references associated with 18:2 Cholesteryl ester in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 18:2 Cholesteryl ester

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 18:2 Cholesteryl ester

MeSH term MeSH ID Detail
Arteriosclerosis D001161 86 associated lipids
Niemann-Pick Diseases D009542 25 associated lipids
Total 2

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 18:2 Cholesteryl ester

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Hyman MD et al. Assessing methods for measuring compliance with a fat-controlled diet. 1982 Am J Public Health pmid:7055316
Sattler W et al. Reduction of HDL- and LDL-associated cholesterylester and phospholipid hydroperoxides by phospholipid hydroperoxide glutathione peroxidase and Ebselen (PZ 51). 1994 Arch. Biochem. Biophys. pmid:8135530
Boer JM et al. Interactions between lifestyle-related factors and the ApoE polymorphism on plasma lipids and apolipoproteins. The EARS Study. European Atherosclerosis Research Study. 1997 Arterioscler. Thromb. Vasc. Biol. pmid:9327762
Ohshiro T et al. Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia. 2011 Arterioscler. Thromb. Vasc. Biol. pmid:21393580
Huber J et al. Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway. 2002 Arterioscler. Thromb. Vasc. Biol. pmid:11950694
Stein O et al. Verapamil enhances receptor-mediated endocytosis of low density lipoproteins by aortic cells in culture. 1985 Jan-Feb Arteriosclerosis pmid:3966907
Goldstein JL et al. Stimulation of cholesteryl ester synthesis in macrophages by extracts of atherosclerotic human aortas and complexes of albumin/cholesteryl esters. 1981 May-Jun Arteriosclerosis pmid:7295194
Carpenter KL et al. Oxidation of cholesteryl linoleate by human monocyte-macrophages in vitro. 1990 Atherosclerosis pmid:2122906
Lee ES et al. The regional ratio of cholesteryl palmitate to cholesteryl oleate measured by ToF-SIMS as a key parameter of atherosclerosis. 2013 Atherosclerosis pmid:23245508
Reid VC et al. Cellular damage in mouse peritoneal macrophages exposed to cholesteryl linoleate. 1992 Atherosclerosis pmid:1632853
Hunt JV et al. Flow cytometric measurement of ceroid accumulation in macrophages. 1993 Atherosclerosis pmid:8457262
Weinmann P et al. Quantitative analysis of cholesterol and cholesteryl esters in human atherosclerotic plaques using near-infrared Raman spectroscopy. 1998 Atherosclerosis pmid:9733218
Yamamoto Y and Niki E Presence of cholesteryl ester hydroperoxide in human blood plasma. 1989 Biochem. Biophys. Res. Commun. pmid:2610703
Takahashi Y et al. Selective uptake and efflux of cholesteryl linoleate in LDL by macrophages expressing 12/15-lipoxygenase. 2005 Biochem. Biophys. Res. Commun. pmid:16105647
Christison J et al. Rapid reduction and removal of HDL- but not LDL-associated cholesteryl ester hydroperoxides by rat liver perfused in situ. 1996 Biochem. J. pmid:8615764
Hunt JV et al. Oxidative alterations in the experimental glycation model of diabetes mellitus are due to protein-glucose adduct oxidation. Some fundamental differences in proposed mechanisms of glucose oxidation and oxidant production. 1993 Biochem. J. pmid:8484733
Bagnati M et al. When and why a water-soluble antioxidant becomes pro-oxidant during copper-induced low-density lipoprotein oxidation: a study using uric acid. 1999 Biochem. J. pmid:10229669
Ferreira AM et al. Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate. 2009 Biochem. J. pmid:18671672
Mazzone T and Pustelnikas L Growth-related modulation of human skin fibroblast cholesterol distribution and metabolism. 1990 Biochim. Biophys. Acta pmid:2248975
Dorset DL Binary phase behavior of cholesteryl oleate with cholesteryl linoleate. 1990 Biochim. Biophys. Acta pmid:2397245
Dorset DL Eutectic interactions between saturated and unsaturated chain cholesteryl esters: comparison of calculated and observed phase diagrams. 1990 Biochim. Biophys. Acta pmid:2223859
Rajan VP and Menon KM Differential uptake and metabolism of free and esterified cholesterol from high-density lipoproteins in the ovary. 1988 Biochim. Biophys. Acta pmid:3128333
Stein Y et al. The fate of cholesteryl linoleyl ether and cholesteryl linoleate in the intact rat after injection of biologically labeled human low density lipoprotein. 1981 Biochim. Biophys. Acta pmid:7213787
Chajek-Shaul T et al. Role of lipoprotein lipase in the uptake of cholesteryl ester by rat lactating mammary gland in vivo. 1981 Biochim. Biophys. Acta pmid:7306561
Takeda S et al. Cannabidiol-2',6'-dimethyl ether as an effective protector of 15-lipoxygenase-mediated low-density lipoprotein oxidation in vitro. 2011 Biol. Pharm. Bull. pmid:21804214
Guo W and Hamilton JA Phase behavior and crystalline structures of cholesteryl ester mixtures: a C-13 MASNMR study. 1995 Biophys. J. pmid:7647242
Yamauchi R et al. Preparation of the addition products of alpha-tocopherol with cholesteryl linoleate-peroxyl radicals. 2002 Biosci. Biotechnol. Biochem. pmid:12005069
Mori S et al. Biosynthesis of cholesterol linoleate by polyethylene glycol-modified cholesterol esterase in organic solvents. 1992 Biotechnol. Appl. Biochem. pmid:1388820
Ball RY et al. Ceroid accumulation by murine peritoneal macrophages exposed to artificial lipoproteins: ultrastructural observations. 1988 Br J Exp Pathol pmid:3348959
Ball RY et al. Ceroid accumulation by murine peritoneal macrophages exposed to artificial lipoproteins. 1987 Br J Exp Pathol pmid:3620335
Tellez A et al. Intramural coronary lipid injection induces atheromatous lesions expressing proinflammatory chemokines: implications for the development of a porcine model of atherosclerosis. 2011 Sep-Oct Cardiovasc Revasc Med pmid:21616727
Kenar JA et al. Identification and quantification of regioisomeric cholesteryl linoleate hydroperoxides in oxidized human low density lipoprotein and high density lipoprotein. 1996 Chem. Res. Toxicol. pmid:8831818
Kawano M et al. Slow beta-migrating lipoprotein: an atherogenic subclass of low density lipoproteins. 1996 Clin. Biochem. pmid:8740510
Luechapudiporn R et al. The reduction of cholesteryl linoleate in lipoproteins: an index of clinical severity in beta-thalassemia/Hb E. 2006 Clin. Chem. Lab. Med. pmid:16681427
Schriewer H et al. Preparation of high-density lipoproteins labelled exclusively at the cholesteryl ester moiety. 1982 Clin. Chim. Acta pmid:7116635
Granada JF et al. Endovascular needle injection of cholesteryl linoleate into the arterial wall produces complex vascular lesions identifiable by intravascular ultrasound: early development in a porcine model of vulnerable plaque. 2005 Coron. Artery Dis. pmid:15915073
Rajan VP and Menon KM Cholesterol flux between high density lipoproteins and cultured rat luteal cells. 1989 Endocrinology pmid:2924727
Thompson SN Brachymeria lasus and Pachycrepoideus vindemiae: sterol requirements during larval growth of two hymenopterous insect parasites reared in vitro on chemically defined media. 1981 Exp. Parasitol. pmid:7202633
Hunt JV et al. Ascorbic acid oxidation: a potential cause of the elevated severity of atherosclerosis in diabetes mellitus? 1992 FEBS Lett. pmid:1397304
Miyoshi N et al. Occurrence of cytotoxic 9-oxononanoyl secosterol aldehydes in human low-density lipoprotein. 2013 Free Radic. Biol. Med. pmid:23395781
Yamamoto Y Fate of lipid hydroperoxides in blood plasma. 2000 Free Radic. Res. pmid:11237101
Suarna C et al. Separation and characterization of cholesteryl oxo- and hydroxy-linoleate isolated from human atherosclerotic plaque. 1997 Free Radic. Res. pmid:9416468
Almeida CP et al. Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake. 2010 Int J Nanomedicine pmid:20957219
Kroon PA and Krieger M The mobility of cholesteryl esters in native and reconstituted low density lipoprotein as monitored by nuclear magnetic resonance spectroscopy. 1981 J. Biol. Chem. pmid:7240142
Lange Y et al. The fate of cholesterol exiting lysosomes. 1997 J. Biol. Chem. pmid:9202016
Sugii S et al. Roles of endogenously synthesized sterols in the endocytic pathway. 2006 J. Biol. Chem. pmid:16737966
Millard EE et al. Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis. 2000 J. Biol. Chem. pmid:10964915
Belkner J et al. The rabbit 15-lipoxygenase preferentially oxygenates LDL cholesterol esters, and this reaction does not require vitamin E. 1998 J. Biol. Chem. pmid:9722553
Sparks DL et al. Effects of the neutral lipid content of high density lipoprotein on apolipoprotein A-I structure and particle stability. 1995 J. Biol. Chem. pmid:7592936