| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gao H and Tan TW | [Analysis of parameters for optimum of ergosterol fermentation]. | 2001 | Sheng Wu Gong Cheng Xue Bao | pmid:11910767 |
| Heimark L et al. | Mechanism of azole antifungal activity as determined by liquid chromatographic/mass spectrometric monitoring of ergosterol biosynthesis. | 2002 | J Mass Spectrom | pmid:11921367 |
| Webb GP and Taylor TG | Effects of ergosterol and adrenalectomy on the maintenance of pregnancy in the ovariectomized rat. | 1977 | Comp Biochem Physiol A Comp Physiol | pmid:11935 |
| Mogensen JE et al. | The major birch allergen, Bet v 1, shows affinity for a broad spectrum of physiological ligands. | 2002 | J. Biol. Chem. | pmid:11953433 |
| Barrero AF et al. | Sterols in erg mutants of Phycomyces: metabolic pathways and physiological effects. | 2002 | Steroids | pmid:11958798 |
| Matsumori N et al. | Amphotericin B covalent dimers forming sterol-dependent ion-permeable membrane channels. | 2002 | J. Am. Chem. Soc. | pmid:11960425 |
| Eroglu C et al. | Functional reconstitution of purified metabotropic glutamate receptor expressed in the fly eye. | 2002 | EMBO Rep. | pmid:11964379 |
| Clark AJ | My hand was on the doorknob to leave. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11969211 |
| Bhattacharya SK et al. | Effect of Withania somnifera glycowithanolides on a rat model of tardive dyskinesia. | 2002 | Phytomedicine | pmid:11995951 |
| Gilbert J et al. | Comparison of Canadian Fusarium graminearum isolates for aggressiveness, vegetative compatibility, and production of ergosterol and mycotoxins. | 2002 | Mycopathologia | pmid:12014482 |
| McDonough V et al. | Mutations in erg4 affect the sensitivity of Saccharomyces cerevisiae to medium-chain fatty acids. | 2002 | Biochim. Biophys. Acta | pmid:12020638 |
| Kuria KA et al. | The antiplasmodial activity of isolates from Ajuga remota. | 2002 | J. Nat. Prod. | pmid:12027771 |
| Barajas-Aceves M et al. | Effect of pollutants on the ergosterol content as indicator of fungal biomass. | 2002 | J. Microbiol. Methods | pmid:12031573 |
| Zhao J et al. | Withanolide derivatives from the roots of Withania somnifera and their neurite outgrowth activities. | 2002 | Chem. Pharm. Bull. | pmid:12045329 |
| Igarashi Y et al. | Anicequol, a novel inhibitor for anchorage-independent growth of tumor cells from Penicillium aurantiogriseum Dierckx TP-F0213. | 2002 | J. Antibiot. | pmid:12061544 |
| Huang D et al. | Dissection of a complex phenotype by functional genomics reveals roles for the yeast cyclin-dependent protein kinase Pho85 in stress adaptation and cell integrity. | 2002 | Mol. Cell. Biol. | pmid:12077337 |
| Baranova NA et al. | [Micromycetes metabolites--inhibitors of growth and sterol biosynthesis in yeasts]. | 2002 | Antibiot. Khimioter. | pmid:12077938 |
| Jelen HH et al. | Influence of octanoic acid addition to medium on some volatile compounds and PR-toxin biosynthesis by Penicillium roqueforti. | 2002 | Lett. Appl. Microbiol. | pmid:12081547 |
| Rebsamen MC et al. | 1alpha,25-dihydroxyvitamin D3 induces vascular smooth muscle cell migration via activation of phosphatidylinositol 3-kinase. | 2002 | Circ. Res. | pmid:12114317 |
| Shen P et al. | A new ergostanol saponin from Dioscorea deltoidea Wall var. orbiculata. | 2002 | J Asian Nat Prod Res | pmid:12118511 |