| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| ROSENKRANTZ H et al. | Infra-red absorption of sterols. I. Ergosterol and related sterols. | 1952 | J. Biol. Chem. | pmid:14946159 |
| STOUDT TH and FOSTER JW | The microbiological synthesis of ergosterol. I. Assay procedure. | 1954 | Appl Microbiol | pmid:13229297 |
| DULANEY EL et al. | Studies on ergosterol production by yeasts. | 1954 | Appl Microbiol | pmid:13229294 |
| FESTENSTEIN GN and MORTON RA | Provitamin D in animal tissues. | 1955 | Biochem. J. | pmid:14363178 |
| FESTENSTEIN GN | The effect of ergosterol and ergocalciferol on the anaerobic glycolysis of rat-liver slices. | 1955 | Biochem. J. | pmid:14363154 |
| GLOVER J et al. | Sterol metabolism. 2. The absorption and metabolism of [14C] ergosterol in the guinea pig. | 1957 | Biochem. J. | pmid:13445674 |
| GLOVER J and LEAT WM | Sterol metabolism. I. The biosynthesis of [14C] ergosterol in Carpenteles brefeldianum Dodge. | 1957 | Biochem. J. | pmid:13445673 |
| ALEXANDER GJ and SCHWENK E | Biogenesis of yeast sterols. IV. Transmethylation in ergosterol synthesis. | 1958 | J. Biol. Chem. | pmid:13549446 |
| ALEXANDER GJ et al. | Biogenesis of yeast sterols. III. The origin of carbon 28 of ergosterol. | 1958 | J. Biol. Chem. | pmid:13549445 |
| CLARK AJ and BLOCH K | Conversion of ergosterol to 22-de-hydrocholesterol in Blattella germanica. | 1959 | J. Biol. Chem. | pmid:13810424 |
| TSUDA S and TATUM EL | Intracellular crystalline ergosterol in Neurospora. | 1961 | J Biophys Biochem Cytol | pmid:13922856 |
| STARR PR and PARKS LW | Some factors affecting sterol formation in Saccharomyces cerevisiae. | 1962 | J. Bacteriol. | pmid:13916377 |
| SMITH PF | Fate of ergosterol and cholestanol in pleuro-pneumonia-like organisms. | 1962 | J. Bacteriol. | pmid:13989541 |
| PARKS LW and STARR PR | A relationship between ergosterol and respiratory competency in yeast. | 1963 | J Cell Comp Physiol | pmid:13941539 |
| REYES P et al. | THE MECHANISM OF BETA-IONONE STIMULATION OF CAROTENOID AND ERGOSTEROL BIOSYNTHESIS IN PHYCOMYCES BLAKESLEEANUS. | 1964 | Biochim. Biophys. Acta | pmid:14237866 |
| VANETTEN JL and GOTTLIEB D | BIOCHEMICAL CHANGES DURING THE GROWTH OF FUNGI. II. ERGOSTEROL AND FATTY ACIDS IN PENICILLIUM ATROVENETUM. | 1965 | J. Bacteriol. | pmid:14255708 |
| TURNER JR and PARKS LW | TRANSMETHYLATION PRODUCTS AS INTERMEDIATES IN ERGOSTEROL BIOSYNTHESIS IN YEAST. | 1965 | Biochim. Biophys. Acta | pmid:14320233 |
| Mulder FJ et al. | Chemical analysis of vitamin D in concentrates and its problems. XII. Analysis of fat-soluble vitamins. | 1971 | J Assoc Off Anal Chem | pmid:5317173 |
| Barton DH et al. | Biosynthesis of terpenes and steroids. 8. The synthesis and metabolism in Saccharomyces cerevisiae of ergosta-7,22,24(28)-trien-3 -ol. | 1972 | J. Chem. Soc. Perkin Trans. I | pmid:4556427 |
| Barton DH et al. | Investigations on the biosynthesis of steroids and terpenoids. VI. The sterols of yeast. | 1972 | J. Chem. Soc. Perkin Trans. I | pmid:4559567 |