| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:28384139 | ||||
| pmid:28395217 | ||||
| pmid:28397534 | ||||
| pmid:28414246 | ||||
| Qin L et al. | Deciphering the Regulatory Network between the SREBP Pathway and Protein Secretion in Neurospora crassa. | 2017 | MBio | pmid:28420736 |
| pmid:28421816 | ||||
| pmid:28429058 | ||||
| Krogerus K et al. | Inheritance of brewing-relevant phenotypes in constructed Saccharomyces cerevisiae × Saccharomyces eubayanus hybrids. | 2017 | Microb. Cell Fact. | pmid:28431563 |
| pmid:28436318 | ||||
| pmid:28461316 | ||||
| Ruan R et al. | Functional analysis of two sterol regulatory element binding proteins in Penicillium digitatum. | 2017 | PLoS ONE | pmid:28467453 |
| Favarin BZ et al. | Effect of the presence of cholesterol in the interfacial microenvironment on the modulation of the alkaline phosphatase activity during in vitro mineralization. | 2017 | Colloids Surf B Biointerfaces | pmid:28472750 |
| pmid:28486854 | ||||
| Vanden Bossche H et al. | Mode of action studies. Basis for the search of new antifungal drugs. | 1988 | Ann. N. Y. Acad. Sci. | pmid:2850749 |
| pmid:28508676 | ||||
| pmid:28509846 | ||||
| pmid:28526017 | ||||
| Voigt WH | On the mode of action of antimycotics, especially of clotrimazole (Canesten), on the ultrastructural level of human pathogenic fungi. | 1978 | Scand J Infect Dis Suppl | pmid:285460 |
| pmid:28584159 | ||||
| pmid:28605335 | ||||
| pmid:28605340 | ||||
| pmid:28605342 | ||||
| Mwenechanya R et al. | Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana. | 2017 | PLoS Negl Trop Dis | pmid:28622334 |
| pmid:28640190 | ||||
| Zulueta DÃaz YLM and Fanani ML | Crossregulation between the insertion of Hexadecylphosphocholine (miltefosine) into lipid membranes and their rheology and lateral structure. | 2017 | Biochim. Biophys. Acta | pmid:28642044 |
| pmid:28643626 | ||||
| pmid:28686900 | ||||
| pmid:28700974 | ||||
| Qi Y et al. | Med15B Regulates Acid Stress Response and Tolerance in Candida glabrata by Altering Membrane Lipid Composition. | 2017 | Appl. Environ. Microbiol. | pmid:28710262 |
| Gebreyesus T et al. | Minor and trace sterols in marine invertebrates 55. The isolation, structure elucidation and synthesis of ergosta-5, 24(28), 25-trien-3 beta-ol. | 1985 | Steroids | pmid:2871644 |
| pmid:28720726 | ||||
| pmid:28741954 | ||||
| pmid:28763757 | ||||
| pmid:28766033 | ||||
| pmid:28768829 | ||||
| Servouse M and Karst F | Regulation of early enzymes of ergosterol biosynthesis in Saccharomyces cerevisiae. | 1986 | Biochem. J. | pmid:2880580 |
| Payne NI et al. | In-vivo studies of amphotericin B liposomes derived from proliposomes: effect of formulation on toxicity and tissue disposition of the drug in mice. | 1987 | J. Pharm. Pharmacol. | pmid:2880979 |
| pmid:29069442 | ||||
| pmid:29101531 | ||||
| pmid:29122611 | ||||
| pmid:29149595 | ||||
| Gao Y et al. | In Vitro and In Vivo Activity of Fomitopsis Pinicola (Sw. Ex Fr.) Karst Chloroform (Fpkc) Extract Against S180 Tumor Cells. | 2017 | Cell. Physiol. Biochem. | pmid:29241162 |
| Capuozzo E and Bolard J | Interaction of the polyene antibiotic etruscomycin with large unilamellar lipid vesicles: binding and proton permeability inducement. | 1985 | Biochim. Biophys. Acta | pmid:2996598 |
| Dahl JS and Dahl CE | Stimulation of cell proliferation and polyphosphoinositide metabolism in Saccharomyces cerevisiae GL7 by ergosterol. | 1985 | Biochem. Biophys. Res. Commun. | pmid:3002372 |
| Rippon JW | A new era in antimycotic agents. | 1986 | Arch Dermatol | pmid:3006601 |
| Kametani T and Furuyama H | Synthesis of vitamin D3 and related compounds. | 1987 Apr-Jun | Med Res Rev | pmid:3033409 |
| Nes WR and Dhanuka IC | Inhibition of sterol synthesis by delta 5-sterols in a sterol auxotroph of yeast defective in oxidosqualene cyclase and cytochrome P-450. | 1988 | J. Biol. Chem. | pmid:3042783 |
| Gruda I et al. | Effects of the detergent sucrose monolaurate on binding of amphotericin B to sterols and its toxicity for cells. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3044370 |
| Watson PF et al. | Isolation and analysis of ketoconazole resistant mutants of Saccharomyces cerevisiae. | 1988 | J. Med. Vet. Mycol. | pmid:3050008 |
| Lewis TL et al. | Pleiotropic mutations in Saccharomyces cerevisiae affecting sterol uptake and metabolism. | 1988 | Yeast | pmid:3059715 |
| Novotný C et al. | Sterol composition of a delta 5,7-sterol-rich strain of Saccharomyces cerevisiae during batch growth. | 1988 | Folia Microbiol. (Praha) | pmid:3060417 |
| Sperka-Gottlieb CD et al. | Lipid topology and physical properties of the outer mitochondrial membrane of the yeast, Saccharomyces cerevisiae. | 1988 | Biochim. Biophys. Acta | pmid:3061466 |
| Ryder NS | Mechanism of action and biochemical selectivity of allylamine antimycotic agents. | 1988 | Ann. N. Y. Acad. Sci. | pmid:3063168 |
| Klimashina MM et al. | [Analysis of the products of ergosta-7,22-dien-3-beta-ol biotransformation by a Nocardia erythropolis culture]. | 1988 Sep-Oct | Prikl. Biokhim. Mikrobiol. | pmid:3072561 |
| Mpona-Minga M et al. | [Effect of a subinhibitory dose of amphotericin B on cellular fatty acid and sterol composition of Candida albicans]. | 1988 Sep-Oct | Ann. Inst. Pasteur Microbiol. | pmid:3075500 |
| Umeki S and Nozawa Y | Sterol manipulation that modulates the alteration in membrane fluidity of Tetrahymena pyriformis during temperature acclimation. | 1986 | Biol. Chem. Hoppe-Seyler | pmid:3085690 |
| Smutzer G | A fluorescent sterol probe study of cholesterol/phospholipid membranes. | 1988 | Biochim. Biophys. Acta | pmid:3207744 |
| Cooper AB et al. | Synthesis and antifungal properties of 14-aminomethyl-substituted lanosterol derivatives. | 1988 | Ann. N. Y. Acad. Sci. | pmid:3214062 |
| Whitaker BD and Nelson DL | Sterol synergism in Paramecium tetraurelia. | 1988 | J. Gen. Microbiol. | pmid:3221193 |
| Kosikov KV et al. | [Ergosterol synthesis by hybrids and strains of yeasts of the genus saccharomyces with different ploidies]. | 1977 Jan-Feb | Mikrobiologiia | pmid:323651 |
| Mehdi H et al. | Sterols of Acanthamoeba culbertsoni strain A-1. | 1988 May-Jun | Steroids | pmid:3242176 |
| Begum VH and Sadique J | Long term effect of herbal drug Withania somnifera on adjuvant induced arthritis in rats. | 1988 | Indian J. Exp. Biol. | pmid:3248848 |
| Lu ZR et al. | Studies on application of a lead acetate solution as filter to the photochemical reaction of ergosterol to improve the yield of vitamin D. | 1988 | J. Nutr. Sci. Vitaminol. | pmid:3263482 |
| Chéron M et al. | Quantitative structure-activity relationships in amphotericin B derivatives. | 1988 | Biochem. Pharmacol. | pmid:3278711 |
| MikhaÄlova NP et al. | [Evaluation of the vitamin D activity of yeasts with altered sterol metabolism]. | 1988 Jan-Feb | Prikl. Biokhim. Mikrobiol. | pmid:3285341 |
| Bottema CK and Parks LW | Delta14-sterol reductase in Saccharomyces cerevisiae. | 1978 | Biochim. Biophys. Acta | pmid:32908 |
| Sokol-Anderson M et al. | Role of cell defense against oxidative damage in the resistance of Candida albicans to the killing effect of amphotericin B. | 1988 | Antimicrob. Agents Chemother. | pmid:3293525 |
| Lorenz RT and Parks LW | Regulation of ergosterol biosynthesis and sterol uptake in a sterol-auxotrophic yeast. | 1987 | J. Bacteriol. | pmid:3301810 |
| Nagai J et al. | Occurrence of fatty acid esters of sterol intermediates in ergosterol synthesis by yeast during respiratory adaptation. | 1977 | J. Biochem. | pmid:330516 |
| M'Baya B and Karst F | In vitro assay of squalene epoxidase of Saccharomyces cerevisiae. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3307781 |
| Bard M et al. | Characterization of a cytochrome P450 deficient mutant of Candida albicans. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3307785 |
| Bard M et al. | Sterol mutants of Saccharomyces cerevisiae: chromatographic analyses. | 1977 | Lipids | pmid:331007 |
| Hays PR et al. | Accumulation of ergosta-8,14-dien-3beta-ol by Saccharomyces cerevisiae cultured with an azasterol antimycotic agent. | 1977 | Lipids | pmid:331008 |
| Hays PR et al. | Physiological effects of an antimycotic azasterol on cultures of Saccharomyces cerevisiae. | 1977 | Antimicrob. Agents Chemother. | pmid:332071 |
| Greenspan MD and Mackow RC | The effct of cerulenin on sterol biosynthesis in Saccharomyces cerevisiae. | 1977 | Lipids | pmid:333217 |
| Smutzer G | A fluorescent sterol probe study of human serum low-density lipoproteins. | 1988 | Biochim. Biophys. Acta | pmid:3342245 |
| Sarachek A | Ergosterol-enhanced recovery of mutagen treated Candida albicans. | 1977 | Z. Allg. Mikrobiol. | pmid:337692 |
| Sashidhar RB et al. | Enhanced fluorescence of ergosterol by iodination and determination of ergosterol by fluorodensitometry. | 1988 | Analyst | pmid:3414969 |
| Nemecz G et al. | A fluorescence and radiolabel study of sterol exchange between membranes. | 1988 | Biochim. Biophys. Acta | pmid:3415992 |
| Müller HM and Lehn C | [Ergosterol as a measure of fungus growth in fodder. I. Ergosterol content of grain]. | 1988 | Arch Tierernahr | pmid:3421835 |
| Osumi T et al. | Studies on the delta 5-desaturation in ergosterol biosynthesis in yeast. | 1979 | J. Biochem. | pmid:34600 |
| Osumi T et al. | Ergosterol biosynthesis in yeast. Pathways in the late stages and their variation under various conditions. | 1978 | J. Biochem. | pmid:346585 |
| Marxer MA and Studer-Stäheli C | [Clinical study on the effectiveness of Insadol]. | 1978 | SSO Schweiz Monatsschr Zahnheilkd | pmid:349689 |
| Ariga N et al. | Accumulation of zymosterol in yeast grown in the presence of ethionine. | 1978 | J. Biochem. | pmid:350865 |
| Nes WR et al. | Evidence for facilitated transport in the absorption of sterols by Saccharomyces cerevisiae. | 1986 | Lipids | pmid:3515094 |
| Parks LW et al. | An essential fungal growth factor derived from ergosterol: a new end product of sterol biosynthesis in fungi? | 1986 | Lipids | pmid:3515097 |
| Pierce HD et al. | Azasterol inhibitors in yeast. Inhibition of the 24-methylene sterol delta24(28)-reductase and delta24-sterol methyltransferase of Saccharomyces cerevisiae by 23-azacholesterol. | 1978 | Biochim. Biophys. Acta | pmid:352402 |
| Ryder NS et al. | Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate. | 1986 | Antimicrob. Agents Chemother. | pmid:3524433 |
| Ryder NS et al. | Inhibition of fungal and mammalian sterol biosynthesis by 2-aza-2,3-dihydrosqualene. | 1986 | FEBS Lett. | pmid:3525224 |
| van den Bossche H et al. | Biochemical effects of miconazole on fungi. II. Inhibition of ergosterol biosynthesis in Candida albicans. | 1978 | Chem. Biol. Interact. | pmid:352553 |
| Barug D et al. | Action of lombazole, and inhibitor of fungal ergosterol biosynthesis, on Staphylococcus epidermidis. | 1986 | Antimicrob. Agents Chemother. | pmid:3532943 |
| Georgopapadakou NH et al. | Effect of antifungal agents on lipid biosynthesis and membrane integrity in Candida albicans. | 1987 | Antimicrob. Agents Chemother. | pmid:3551826 |
| Nes WR et al. | The functional importance of structural features of ergosterol in yeast. | 1978 | J. Biol. Chem. | pmid:355252 |
| Gorman AA et al. | Ergosterol (provitamin D2) triplet state: an efficient sensitiser of singlet oxygen, O2(1 delta g), formation. | 1987 | Photochem. Photobiol. | pmid:3562585 |
| Fuska J et al. | Microbiological and chemical dehydrogenation of withaferin A. | 1987 | Folia Microbiol. (Praha) | pmid:3583136 |
| Schroeder F et al. | A fluorescence study of dehydroergosterol in phosphatidylcholine bilayer vesicles. | 1987 | Biochemistry | pmid:3607026 |
| Taylor FR and Parks LW | Metabolic interconversion of free sterols and steryl esters in Saccharomyces cerevisiae. | 1978 | J. Bacteriol. | pmid:361713 |
| Sanadi S et al. | Reversal of cerulenin-induced inhibition of phospholipids and sterol synthesis by exogenous fatty acids/sterols in Epidermophyton floccosum. | 1987 | Biochim. Biophys. Acta | pmid:3651491 |
| Parks LW | Metabolism of sterols in yeast. | 1978 | CRC Crit Rev Microbiol | pmid:365459 |
| Kito M et al. | Association of polyene antibiotics with sterols. | 1987 | Chem. Biol. Interact. | pmid:3690724 |