| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cantrell CL et al. | Antimycobacterial plant terpenoids. | 2001 | Planta Med. | pmid:11731906 |
| Sievi E et al. | Proteolytic function of GPI-anchored plasma membrane protease Yps1p in the yeast vacuole and Golgi. | 2001 | Traffic | pmid:11737827 |
| Baas B et al. | Activity and kinetics of dissociation and transfer of amphotericin B from a novel delivery form. | 1999 | AAPS PharmSci | pmid:11741206 |
| Szponar B and Larsson L | Use of mass spectrometry for characterising microbial communities in bioaerosols. | 2001 | Ann Agric Environ Med | pmid:11748866 |
| Mareggiani G et al. | Response of Tribolium castaneum (Coleoptera, Tenebrionidae) to Salpichroa origanifolia Withanolides. | 2002 | J. Agric. Food Chem. | pmid:11754551 |
| Zhang WH and Che CT | Isomalabaricane-type nortriterpenoids and other constituents of the marine sponge Geodia japonica. | 2001 | J. Nat. Prod. | pmid:11754596 |
| Saxena J et al. | Relationship of mould count, ergosterol and ochratoxin A production. | 2001 | Int. J. Food Microbiol. | pmid:11764889 |
| Kircher HW and Rosenstein FU | Reaction of ergosteryl acetate with maleic anhydride and preparation of 5,7-ergostadien-3beta-ol1,2. | 1975 | Lipids | pmid:1177664 |
| Evans EG | The rationale for combination therapy. | 2001 | Br. J. Dermatol. | pmid:11777263 |
| Milhaud J et al. | Interactions of the drug amphotericin B with phospholipid membranes containing or not ergosterol: new insight into the role of ergosterol. | 2002 | Biochim. Biophys. Acta | pmid:11779560 |
| Shin KH et al. | Antioxidant and immunostimulating activities of the fruiting bodies of Paecilomyces japonica, a new type of Cordyceps sp. | 2001 | Ann. N. Y. Acad. Sci. | pmid:11795517 |
| Matsumoto M et al. | Strong antifungal activity of SS750, a new triazole derivative, is based on its selective binding affinity to cytochrome P450 of fungi. | 2002 | Antimicrob. Agents Chemother. | pmid:11796335 |
| Ferber D | Infectious disease. New weapons in the battle of the bugs. | 2002 | Science | pmid:11799221 |
| Lupetti A et al. | Molecular basis of resistance to azole antifungals. | 2002 | Trends Mol Med | pmid:11815273 |
| Harding WW et al. | Cycloartanes, protolimonoids, a pregnane and a new ergostane from Trichilia reticulata. | 2001 | Nat Prod Lett | pmid:11833620 |
| Olsson J et al. | Detection and quantification of ochratoxin A and deoxynivalenol in barley grains by GC-MS and electronic nose. | 2002 | Int. J. Food Microbiol. | pmid:11845819 |
| Hirotani M et al. | Blazeispirols B, C, E and F, des-A-ergostane-type compounds, from the cultured mycelia of the fungus Agaricus blazei. | 2002 | Phytochemistry | pmid:11853754 |
| Suárez Y et al. | Differential effects of ergosterol and cholesterol on Cdk1 activation and SRE-driven transcription. | 2002 | Eur. J. Biochem. | pmid:11895447 |
| Baran M and Mazerski J | Molecular modelling of amphotericin B-ergosterol primary complex in water. | 2002 | Biophys. Chem. | pmid:11897151 |
| Malmstrøm J et al. | Bioactive metabolites from a marine-derived strain of the fungus Emericella variecolor. | 2002 | J. Nat. Prod. | pmid:11908979 |