| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Markowicz P et al. | A study on particles and some microbial markers in waterpipe tobacco smoke. | 2014 | Sci. Total Environ. | pmid:25181042 |
| Kamiński DM | Recent progress in the study of the interactions of amphotericin B with cholesterol and ergosterol in lipid environments. | 2014 | Eur. Biophys. J. | pmid:25173562 |
| Tuckey RC et al. | Lumisterol is metabolized by CYP11A1: discovery of a new pathway. | 2014 | Int. J. Biochem. Cell Biol. | pmid:25130438 |
| Blosser SJ et al. | Two C4-sterol methyl oxidases (Erg25) catalyse ergosterol intermediate demethylation and impact environmental stress adaptation in Aspergillus fumigatus. | 2014 | Microbiology (Reading, Engl.) | pmid:25107308 |
| Van Hauwenhuyse F et al. | Ascorbic acid inhibition of Candida albicans Hsp90-mediated morphogenesis occurs via the transcriptional regulator Upc2. | 2014 | Eukaryotic Cell | pmid:25084864 |
| Wang Y et al. | Investigating migration inhibition and apoptotic effects of Fomitopsis pinicola chloroform extract on human colorectal cancer SW-480 cells. | 2014 | PLoS ONE | pmid:24992193 |
| Term 2. | 2014 | Med Mycol J | pmid:24943213 | |
| Licursi V et al. | The COP9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in Saccharomyces cerevisiae. | 2014 | FEBS J. | pmid:24164706 |
| Tong S et al. | Simultaneous HPLC determination of ergosterol and 22,23-dihydroergosterol in Flammulina velutipes sterol-loaded microemulsion. | 2014 | Biomed. Chromatogr. | pmid:23996456 |
| Kucserka T et al. | Leaf litter decomposition in Torna stream before and after a red mud disaster. | 2014 | Acta. Biol. Hung. | pmid:24561898 |
| Chen YF et al. | Zhankuic acid A isolated from Taiwanofungus camphoratus is a novel selective TLR4/MD-2 antagonist with anti-inflammatory properties. | 2014 | J. Immunol. | pmid:24532584 |
| Nakagawa Y et al. | Effect of sterol side chain on ion channel formation by amphotericin B in lipid bilayers. | 2014 | Biochemistry | pmid:24762132 |
| Ueda Y et al. | Anti-HCV activity of the Chinese medicinal fungus Cordyceps militaris. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24726408 |
| McCulley A et al. | Chemical suppression of defects in mitotic spindle assembly, redox control, and sterol biosynthesis by hydroxyurea. | 2014 | G3 (Bethesda) | pmid:24192836 |
| Mesa-Arango AC et al. | The production of reactive oxygen species is a universal action mechanism of Amphotericin B against pathogenic yeasts and contributes to the fungicidal effect of this drug. | 2014 | Antimicrob. Agents Chemother. | pmid:25155595 |
| da Silva Neto BR et al. | Transcriptional profile of Paracoccidioides spp. in response to itraconazole. | 2014 | BMC Genomics | pmid:24690401 |
| Sonego JM et al. | Synthesis and antifungal activity of C-21 steroids with an aromatic D ring. | 2013 | Steroids | pmid:23499954 |
| Dehedin A et al. | The combined effects of water level reduction and an increase in ammonia concentration on organic matter processing by key freshwater shredders in alluvial wetlands. | 2013 | Glob Chang Biol | pmid:23504834 |
| Debieu D et al. | Role of sterol 3-ketoreductase sensitivity in susceptibility to the fungicide fenhexamid in Botrytis cinerea and other phytopathogenic fungi. | 2013 | Pest Manag. Sci. | pmid:23139232 |
| Herath HM et al. | New secondary metabolites from bioactive extracts of the fungus Armillaria tabescens. | 2013 | Nat. Prod. Res. | pmid:23140424 |