| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Tinea | D014005 | 5 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dadakova K et al. | Elucidation of signaling molecules involved in ergosterol perception in tobacco. | 2013 | Plant Physiol. Biochem. | pmid:24095918 |
| Sonego JM et al. | Synthesis and antifungal activity of C-21 steroids with an aromatic D ring. | 2013 | Steroids | pmid:23499954 |
| Dehedin A et al. | The combined effects of water level reduction and an increase in ammonia concentration on organic matter processing by key freshwater shredders in alluvial wetlands. | 2013 | Glob Chang Biol | pmid:23504834 |
| Cardoso DR et al. | Riboflavin-photosensitized oxidation is enhanced by conjugation in unsaturated lipids. | 2013 | J. Agric. Food Chem. | pmid:23402498 |
| Kang CK et al. | Visualization analysis of the vacuole-targeting fungicidal activity of amphotericin B against the parent strain and an ergosterol-less mutant of Saccharomyces cerevisiae. | 2013 | Microbiology (Reading, Engl.) | pmid:23475946 |
| ValentÃn L et al. | Mycoremediation of wood and soil from an old sawmill area contaminated for decades. | 2013 | J. Hazard. Mater. | pmid:23832059 |
| Wu SH et al. | Two new steroids from an endophytic fungus Phomopsis sp. | 2013 | Chem. Biodivers. | pmid:23847072 |
| Šimová Z et al. | The yeast Saccharomyces cerevisiae Pdr16p restricts changes in ergosterol biosynthesis caused by the presence of azole antifungals. | 2013 | Yeast | pmid:23606207 |
| Eddouzi J et al. | Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitals. | 2013 | Antimicrob. Agents Chemother. | pmid:23629718 |
| Chiu YF et al. | In vivo probing of the temperature responses of intracellular biomolecules in yeast cells by label-free Raman microspectroscopy. | 2013 | Chembiochem | pmid:23630156 |
| Zhang BB et al. | Cytotoxic cholestane-type and ergostane-type steroids from the aerial parts of Euphorbia altotibetic. | 2013 | Steroids | pmid:23131765 |
| Debieu D et al. | Role of sterol 3-ketoreductase sensitivity in susceptibility to the fungicide fenhexamid in Botrytis cinerea and other phytopathogenic fungi. | 2013 | Pest Manag. Sci. | pmid:23139232 |
| Herath HM et al. | New secondary metabolites from bioactive extracts of the fungus Armillaria tabescens. | 2013 | Nat. Prod. Res. | pmid:23140424 |
| Layer JV et al. | Characterization of a mutation that results in independence of oxidosqualene cyclase (Erg7) activity from the downstream 3-ketoreductase (Erg27) in the yeast ergosterol biosynthetic pathway. | 2013 | Biochim. Biophys. Acta | pmid:23022663 |
| Cabral ME et al. | Synergistic antifungal activity of statin-azole associations as witnessed by Saccharomyces cerevisiae- and Candida utilis-bioassays and ergosterol quantification. | 2013 | Rev Iberoam Micol | pmid:23069981 |
| Clemmensen KE et al. | Roots and associated fungi drive long-term carbon sequestration in boreal forest. | 2013 | Science | pmid:23539604 |
| Moretti-Almeida G et al. | The essential gene YMR134W from Saccharomyces cerevisiae is important for appropriate mitochondrial iron utilization and the ergosterol biosynthetic pathway. | 2013 | FEBS Lett. | pmid:23892078 |
| Upadhya R et al. | Sulphiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signalling pathway in Cryptococcus neoformans and contributes to fungal virulence. | 2013 | Mol. Microbiol. | pmid:23998805 |
| Souza-Moreira TM et al. | Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study. | 2013 | Molecules | pmid:23839114 |
| Cicogna F et al. | Interaction of azole compounds with DOPC and DOPC/ergosterol bilayers by spin probe EPR spectroscopy: implications for antifungal activity. | 2013 | J Phys Chem B | pmid:24032998 |