| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Tinea | D014005 | 5 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ohvo-Rekilä H et al. | Cyclodextrin-catalyzed extraction of fluorescent sterols from monolayer membranes and small unilamellar vesicles. | 2000 | Chem. Phys. Lipids | pmid:10823464 |
| Ohnuma N et al. | Sterol constituents from two edible mushrooms, Lentinula edodes and Tricholoma matsutake. | 2000 | Chem. Pharm. Bull. | pmid:10823718 |
| Barton DH and Patin H | Chemistry of the tricarbonyliron complexes of calciferol and ergosterol. | 1976 | J. Chem. Soc. Perkin Trans. I | pmid:1083856 |
| Tsukida K et al. | Simultaneous determination of eight vitamin D2 isomers by proton magnetic resonance spectroscopy. | 1976 | J. Nutr. Sci. Vitaminol. | pmid:1085350 |
| Múcková M et al. | Synergy between 6-amino-2-n-pentylthiobenzothiazole and ergosterol biosynthesis-inhibiting antimycotics against Candida albicans in vitro. | 2000 | Int. J. Antimicrob. Agents | pmid:10854813 |
| Aceves MB | Soil ergosterol, dimethyl sulphide reduction, and microbial biomass along a Zn concentrations gradient in soils from a mine spoil tip. | 2000 | Bull Environ Contam Toxicol | pmid:10856334 |
| Schoer JK et al. | Lysosomal membrane cholesterol dynamics. | 2000 | Biochemistry | pmid:10869172 |
| Dales RE et al. | Testing the association between residential fungus and health using ergosterol measures and cough recordings. | 1999 | Mycopathologia | pmid:10872512 |
| Chen TC et al. | An evaluation of the biologic activity and vitamin D receptor binding affinity of the photoisomers of vitamin D3 and previtamin D3. | 2000 | J. Nutr. Biochem. | pmid:10876100 |
| Arthington-Skaggs BA et al. | Quantitation of Candida albicans ergosterol content improves the correlation between in vitro antifungal susceptibility test results and in vivo outcome after fluconazole treatment in a murine model of invasive candidiasis. | 2000 | Antimicrob. Agents Chemother. | pmid:10898679 |
| Nurminen T et al. | Neutral lipids in the cells and cell envelope fractions of aerobic baker's yeast and anaerobic brewer's yeast. | 1975 | Chem. Phys. Lipids | pmid:1091369 |
| Zeppa S et al. | Estimation of fungal biomass and transcript levels in Tilia platyphyllos-Tuber borchii ectomycorrhizae. | 2000 | FEMS Microbiol. Lett. | pmid:10913693 |
| Bailey RB and Parks LW | Potassium translocation in yeast mitochondria and its relationship to ergostrol biosynthesis. | 1975 | J. Bacteriol. | pmid:1092661 |
| Hughes TR et al. | Functional discovery via a compendium of expression profiles. | 2000 | Cell | pmid:10929718 |
| Kontoyiannis DP | Modulation of fluconazole sensitivity by the interaction of mitochondria and erg3p in Saccharomyces cerevisiae. | 2000 | J. Antimicrob. Chemother. | pmid:10933640 |
| Kontoyiannis DP | Efflux-mediated resistance to fluconazole could be modulated by sterol homeostasis in Saccharomyces cerevisiae. | 2000 | J. Antimicrob. Chemother. | pmid:10933641 |
| Barton DH et al. | Biosynthesis of terpenes and steroids. X. The sterols of some yeast mutants doubly defective in ergosterol biosynthesis. | 1975 | J. Chem. Soc. Perkin Trans. I | pmid:1094026 |
| Gale EF et al. | Factors affecting the changes in amphotericin sensitivity of Candida albicans during growth. | 1975 | J. Gen. Microbiol. | pmid:1094096 |
| Pieringer J and Conner RL | Positional distribution of fatty acids in the glycerophospholipids of Tetrahymena pyriformis. | 1979 | J. Lipid Res. | pmid:109555 |
| Avdulov NA et al. | Cholesterol efflux to high-density lipoproteins and apolipoprotein A-I phosphatidylcholine complexes is inhibited by ethanol: role of apolipoprotein structure and cooperative interaction of phosphatidylcholine and cholesterol. | 2000 | Biochemistry | pmid:10956052 |