| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Tinea | D014005 | 5 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lagane B et al. | Role of sterols in modulating the human mu-opioid receptor function in Saccharomyces cerevisiae. | 2000 | J. Biol. Chem. | pmid:10973945 |
| Cardinale F et al. | Differential activation of four specific MAPK pathways by distinct elicitors. | 2000 | J. Biol. Chem. | pmid:10973984 |
| De Lucca AJ et al. | D-cecropin B: proteolytic resistance, lethality for pathogenic fungi and binding properties. | 2000 | Med. Mycol. | pmid:10975698 |
| Mareggiani G et al. | Antifeedant activity of withanolides from Salpichroa origanifolia on Musca domestica. | 2000 | J. Nat. Prod. | pmid:10978207 |
| Shimizu I and Katsuki H | Effect of temperature on ergosterol biosynthesis in yeast. | 1975 | J. Biochem. | pmid:1099086 |
| Henry KW et al. | Upregulation of ERG genes in Candida species by azoles and other sterol biosynthesis inhibitors. | 2000 | Antimicrob. Agents Chemother. | pmid:10991846 |
| Fábry S et al. | Inhibition of germ tube formation, filamentation and ergosterol biosynthesis in Candida albicans treated with 6-amino-2-n-pentylthiobenzothiazole. | 1999 | Folia Microbiol. (Praha) | pmid:10997135 |
| Archer DB | The use of a fluorescent sterol to investigate the mode of action of amphotericin methyl ester, a polyene antibiotic. | 1975 | Biochem. Biophys. Res. Commun. | pmid:1100049 |
| Moreau JP et al. | Biosynthesis of sterols by a yeast homogenate. Incorporation of mevalonic acid into cholesta-5,7,24-trien-3beta-ol and 5alpha-cholesta-7,24-dien-3beta-ol. | 1975 | Eur. J. Biochem. | pmid:1100393 |
| Archer DB and Gale EF | Antagonism by sterols of the action of amphotericin and filipin on the release of potassium ions from Candida albicans and Mycoplasma mycoides subsp. capri. | 1975 | J. Gen. Microbiol. | pmid:1100776 |
| Eliazian AA et al. | [Biosynthesis of sterols by various yeasts]. | 1975 Jul-Aug | Mikrobiologiia | pmid:1100997 |
| Saha AK et al. | Novel antifungals based on 4-substituted imidazole: a combinatorial chemistry approach to lead discovery and optimization. | 2000 | Bioorg. Med. Chem. Lett. | pmid:11012023 |
| Jia MH et al. | Global expression profiling of yeast treated with an inhibitor of amino acid biosynthesis, sulfometuron methyl. | 2000 | Physiol. Genomics | pmid:11015603 |
| Olsson J et al. | Volatiles for mycological quality grading of barley grains: determinations using gas chromatography-mass spectrometry and electronic nose. | 2000 | Int. J. Food Microbiol. | pmid:11020038 |
| Bailey RB and Parks LW | Yeast sterol esters and their relationship to the growth of yeast. | 1975 | J. Bacteriol. | pmid:1102523 |
| Klein HP and Volkmann CM | Factors affecting the palmitoyl-coenzyme A desaturase of Saccharomyces cerevisiae. | 1975 | J. Bacteriol. | pmid:1102529 |
| Tanabe H et al. | Sensitization of chemotactic response by changing the lipid composition of surface membrane in Tetrahymena pyriformis. | 1979 | Biochim. Biophys. Acta | pmid:110345 |
| Neville ME et al. | Differential biosynthesis of polyunsaturated fatty acids by Tetrahymena supplemented with ergosterol. | 1979 | Biochim. Biophys. Acta | pmid:110351 |
| Cui D et al. | [Chemical constituents of Bulgaria inquinans (Fries)]. | 1997 | Zhongguo Zhong Yao Za Zhi | pmid:11038915 |
| Chai H et al. | [Constituents from the fruiting body of Ganoderma lucidum (Fr.) Karst]. | 1997 | Zhongguo Zhong Yao Za Zhi | pmid:11038948 |