| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Tinea | D014005 | 5 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Deng ZY et al. | Resveratrol alleviates vascular inflammatory injury by inhibiting inflammasome activation in rats with hypercholesterolemia and vitamin D2 treatment. | 2015 | Inflamm. Res. | pmid:25833014 |
| Ahluwalia V et al. | Comparative evaluation of two Trichoderma harzianum strains for major secondary metabolite production and antifungal activity. | 2015 | Nat. Prod. Res. | pmid:25248548 |
| Pereira MG et al. | Trypanosoma cruzi Epimastigotes Are Able to Manage Internal Cholesterol Levels under Nutritional Lipid Stress Conditions. | 2015 | PLoS ONE | pmid:26068009 |
| Davis SA et al. | Nontoxic antimicrobials that evade drug resistance. | 2015 | Nat. Chem. Biol. | pmid:26030729 |
| Murley A et al. | Ltc1 is an ER-localized sterol transporter and a component of ER-mitochondria and ER-vacuole contacts. | 2015 | J. Cell Biol. | pmid:25987606 |
| NÃ¥bo LJ et al. | Design of new fluorescent cholesterol and ergosterol analogs: Insights from theory. | 2015 | Biochim. Biophys. Acta | pmid:25963993 |
| Sterkenburg E et al. | Changes in fungal communities along a boreal forest soil fertility gradient. | 2015 | New Phytol. | pmid:25952659 |
| Kim SJ et al. | Beneficial effects of the traditional medicine Igongsan and its constituent ergosterol on dextran sulfate sodium-induced colitis in mice. | 2015 | Mol Med Rep | pmid:26005209 |
| Liu DZ et al. | A new ergostane triterpenoid from a solid culture of the basidiomycete Inocybe lilacina. | 2014 Mar-Apr | Z. Naturforsch., C, J. Biosci. | pmid:24873028 |
| Wang M et al. | Os2 MAP kinase-mediated osmostress tolerance in Penicillium digitatum is associated with its positive regulation on glycerol synthesis and negative regulation on ergosterol synthesis. | 2014 Jul-Aug | Microbiol. Res. | pmid:24439827 |
| Andrade-Pavón D et al. | The 3-hydroxy-3-methylglutaryl coenzyme-A reductases from fungi: a proposal as a therapeutic target and as a study model. | 2014 Jan-Mar | Rev Iberoam Micol | pmid:24270073 |
| Cirlini M et al. | Durum wheat (Triticum Durum Desf.) lines show different abilities to form masked mycotoxins under greenhouse conditions. | 2014 | Toxins (Basel) | pmid:24368326 |
| Choi H et al. | Residential culturable fungi, (1-3, 1-6)-β-d-glucan, and ergosterol concentrations in dust are not associated with asthma, rhinitis, or eczema diagnoses in children. | 2014 | Indoor Air | pmid:24016225 |
| Ruiz M et al. | Ligand binding-dependent functions of the lipocalin NLaz: an in vivo study in Drosophila. | 2014 | FASEB J. | pmid:24361577 |
| Benaim G et al. | Dronedarone, an amiodarone analog with improved anti-Leishmania mexicana efficacy. | 2014 | Antimicrob. Agents Chemother. | pmid:24492373 |
| Pereira DM et al. | Palmitic acid and ergosta-7,22-dien-3-ol contribute to the apoptotic effect and cell cycle arrest of an extract from Marthasterias glacialis L. in neuroblastoma cells. | 2014 | Mar Drugs | pmid:24368569 |
| Yadav B et al. | First step of glycosylphosphatidylinositol (GPI) biosynthesis cross-talks with ergosterol biosynthesis and Ras signaling in Candida albicans. | 2014 | J. Biol. Chem. | pmid:24356967 |
| Huang Y et al. | Antcamphins A-L, ergostanoids from Antrodia camphorata. | 2014 | J. Nat. Prod. | pmid:24387703 |
| Fu Z et al. | Exometabolome analysis reveals hypoxia at the up-scaling of a Saccharomyces cerevisiae high-cell density fed-batch biopharmaceutical process. | 2014 | Microb. Cell Fact. | pmid:24593159 |
| Pourmousa M et al. | Dehydroergosterol as an analogue for cholesterol: why it mimics cholesterol so well-or does it? | 2014 | J Phys Chem B | pmid:24893063 |