| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Tinea | D014005 | 5 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bhattacharya A et al. | Effect of Withania somnifera glycowithanolides on iron-induced hepatotoxicity in rats. | 2000 | Phytother Res | pmid:11054855 |
| Chung SK et al. | Design and synthesis of potential inhibitors of the ergosterol biosynthesis as antifungal agents. | 2000 | Bioorg. Med. Chem. | pmid:11058043 |
| Kitajma Y | [Structural and biochemical characteristics of pathogenic fungus: cell walls, lipids and dimorphism, and action modes of antifungal agents]. | 2000 | Nihon Ishinkin Gakkai Zasshi | pmid:11064317 |
| Misico RI et al. | Withanolides from Vassobia lorentzii. | 2000 | J. Nat. Prod. | pmid:11076546 |
| Yazawa Y et al. | Antitumor promoting effect of an active component of Polyporus, ergosterol and related compounds on rat urinary bladder carcinogenesis in a short-term test with concanavalin A. | 2000 | Biol. Pharm. Bull. | pmid:11085355 |
| Sturley SL | Conservation of eukaryotic sterol homeostasis: new insights from studies in budding yeast. | 2000 | Biochim. Biophys. Acta | pmid:11111085 |
| Nielsen KF and Madsen JO | Determination of ergosterol on mouldy building materials using isotope dilution and gas chromatography-tandem mass spectrometry. | 2000 | J Chromatogr A | pmid:11117420 |
| Mastrolorenzo A et al. | The antifungal activity of sulfonylated/carboxylated derivatives of dibenzo-1,4-dioxine-2-acetyloxime may be due to inhibition of lanosterol-14alpha-demethylase. | 2000 | J. Enzym. Inhib. | pmid:11140611 |
| Toh TH et al. | Quantification of plasma membrane ergosterol of Saccharomyces cerevisiae by direct-injection atmospheric pressure chemical ionization/tandem mass spectrometry. | 2001 | Anal. Biochem. | pmid:11141305 |
| Demaret S et al. | A possible binding path of ergosterol within elicitins revealed by molecular dynamics. | 2000 | J. Biomol. Struct. Dyn. | pmid:11149520 |
| Gachotte D et al. | A novel gene conserved from yeast to humans is involved in sterol biosynthesis. | 2001 | J. Lipid Res. | pmid:11160377 |
| Nerud F and MusÃlek V | Lipids in fruiting bodies of the basidiomycete Oudemansiella mucida. | 1975 | Folia Microbiol. (Praha) | pmid:1116799 |
| Weber N et al. | Fatty acid steryl, stanyl, and steroid esters by esterification and transesterification in vacuo using Candida rugosa lipase as catalyst. | 2001 | J. Agric. Food Chem. | pmid:11170561 |
| Leber R et al. | A novel sequence element is involved in the transcriptional regulation of expression of the ERG1 (squalene epoxidase) gene in Saccharomyces cerevisiae. | 2001 | Eur. J. Biochem. | pmid:11179957 |
| Bhattacharya SK et al. | Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study. | 2000 | Phytomedicine | pmid:11194174 |
| Ponchet M et al. | Are elicitins cryptograms in plant-Oomycete communications? | 1999 | Cell. Mol. Life Sci. | pmid:11212320 |
| Zhu XH et al. | Six new withanolide-type steroids from the leaves of Solanum cilistum. | 2001 | Chem. Pharm. Bull. | pmid:11217102 |
| Ragsdale NN | Specific effects of triarimol on sterol biosynthesis in Ustilago maydis. | 1975 | Biochim. Biophys. Acta | pmid:1122314 |
| Osman H et al. | Fatty acids bind to the fungal elicitor cryptogein and compete with sterols. | 2001 | FEBS Lett. | pmid:11231013 |
| Beh CT et al. | Overlapping functions of the yeast oxysterol-binding protein homologues. | 2001 | Genetics | pmid:11238399 |