| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Filipiak M and Weiner J | How to make a beetle out of wood: multi-elemental stoichiometry of wood decay, xylophagy and fungivory. | 2014 | PLoS ONE | pmid:25536334 |
| Cirlini M et al. | Durum wheat (Triticum Durum Desf.) lines show different abilities to form masked mycotoxins under greenhouse conditions. | 2014 | Toxins (Basel) | pmid:24368326 |
| Choi H et al. | Residential culturable fungi, (1-3, 1-6)-β-d-glucan, and ergosterol concentrations in dust are not associated with asthma, rhinitis, or eczema diagnoses in children. | 2014 | Indoor Air | pmid:24016225 |
| Gu M et al. | Structure-activity relationship (SAR) of withanolides to inhibit Hsp90 for its activity in pancreatic cancer cells. | 2014 | Invest New Drugs | pmid:23887853 |
| Ruiz M et al. | Ligand binding-dependent functions of the lipocalin NLaz: an in vivo study in Drosophila. | 2014 | FASEB J. | pmid:24361577 |
| Ren B et al. | ABC transporters coupled with the elevated ergosterol contents contribute to the azole resistance and amphotericin B susceptibility. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24435642 |
| Caspeta L et al. | Biofuels. Altered sterol composition renders yeast thermotolerant. | 2014 | Science | pmid:25278608 |
| Cheng C and Kao KC | Microbiology. How to survive being hot and inebriated. | 2014 | Science | pmid:25278598 |
| Benaim G et al. | Dronedarone, an amiodarone analog with improved anti-Leishmania mexicana efficacy. | 2014 | Antimicrob. Agents Chemother. | pmid:24492373 |
| Pereira DM et al. | Palmitic acid and ergosta-7,22-dien-3-ol contribute to the apoptotic effect and cell cycle arrest of an extract from Marthasterias glacialis L. in neuroblastoma cells. | 2014 | Mar Drugs | pmid:24368569 |
| Yadav B et al. | First step of glycosylphosphatidylinositol (GPI) biosynthesis cross-talks with ergosterol biosynthesis and Ras signaling in Candida albicans. | 2014 | J. Biol. Chem. | pmid:24356967 |
| Huang Y et al. | Antcamphins A-L, ergostanoids from Antrodia camphorata. | 2014 | J. Nat. Prod. | pmid:24387703 |
| Ekinci R et al. | Patulin & ergosterol: new quality parameters together with aflatoxins in hazelnuts. | 2014 | Food Chem | pmid:24360413 |
| Matsushika A et al. | Transcription analysis of recombinant industrial and laboratory Saccharomyces cerevisiae strains reveals the molecular basis for fermentation of glucose and xylose. | 2014 | Microb. Cell Fact. | pmid:24467867 |
| Chen YF et al. | Zhankuic acid A as a novel JAK2 inhibitor for the treatment of concanavalin A-induced hepatitis. | 2014 | Biochem. Pharmacol. | pmid:25076381 |
| Fu Z et al. | Exometabolome analysis reveals hypoxia at the up-scaling of a Saccharomyces cerevisiae high-cell density fed-batch biopharmaceutical process. | 2014 | Microb. Cell Fact. | pmid:24593159 |
| Waśkiewicz A et al. | Deoxynivalenol and oxidative stress indicators in winter wheat inoculated with Fusarium graminearum. | 2014 | Toxins (Basel) | pmid:24514944 |
| Pereira DM et al. | Anti-inflammatory effect of unsaturated fatty acids and Ergosta-7,22-dien-3-ol from Marthasterias glacialis: prevention of CHOP-mediated ER-stress and NF-κB activation. | 2014 | PLoS ONE | pmid:24551093 |
| Foglia F et al. | Interaction of amphotericin B with lipid monolayers. | 2014 | Langmuir | pmid:25019324 |
| Pourmousa M et al. | Dehydroergosterol as an analogue for cholesterol: why it mimics cholesterol so well-or does it? | 2014 | J Phys Chem B | pmid:24893063 |