| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhang X et al. | Characterization of Tamoxifen as an Antifungal Agent Using the Yeast Schizosaccharomyces Pombe Model Organism. | 2015 | Kobe J Med Sci | pmid:26628015 |
| Fiedler S and Heerklotz H | Vesicle Leakage Reflects the Target Selectivity of Antimicrobial Lipopeptides from Bacillus subtilis. | 2015 | Biophys. J. | pmid:26588567 |
| Deng ZY et al. | Resveratrol alleviates vascular inflammatory injury by inhibiting inflammasome activation in rats with hypercholesterolemia and vitamin D2 treatment. | 2015 | Inflamm. Res. | pmid:25833014 |
| Ahluwalia V et al. | Comparative evaluation of two Trichoderma harzianum strains for major secondary metabolite production and antifungal activity. | 2015 | Nat. Prod. Res. | pmid:25248548 |
| Pereira MG et al. | Trypanosoma cruzi Epimastigotes Are Able to Manage Internal Cholesterol Levels under Nutritional Lipid Stress Conditions. | 2015 | PLoS ONE | pmid:26068009 |
| Davis SA et al. | Nontoxic antimicrobials that evade drug resistance. | 2015 | Nat. Chem. Biol. | pmid:26030729 |
| Murley A et al. | Ltc1 is an ER-localized sterol transporter and a component of ER-mitochondria and ER-vacuole contacts. | 2015 | J. Cell Biol. | pmid:25987606 |
| NÃ¥bo LJ et al. | Design of new fluorescent cholesterol and ergosterol analogs: Insights from theory. | 2015 | Biochim. Biophys. Acta | pmid:25963993 |
| Sterkenburg E et al. | Changes in fungal communities along a boreal forest soil fertility gradient. | 2015 | New Phytol. | pmid:25952659 |
| Leiva K et al. | Identification and functional characterization of the CYP51 gene from the yeast Xanthophyllomyces dendrorhous that is involved in ergosterol biosynthesis. | 2015 | BMC Microbiol. | pmid:25906980 |
| McCall LI et al. | Targeting Ergosterol biosynthesis in Leishmania donovani: essentiality of sterol 14 alpha-demethylase. | 2015 | PLoS Negl Trop Dis | pmid:25768284 |
| Ano Y et al. | Identification of a novel dehydroergosterol enhancing microglial anti-inflammatory activity in a dairy product fermented with Penicillium candidum. | 2015 | PLoS ONE | pmid:25760331 |
| Luna-Tapia A et al. | Trafficking through the late endosome significantly impacts Candida albicans tolerance of the azole antifungals. | 2015 | Antimicrob. Agents Chemother. | pmid:25666149 |
| Kim SJ et al. | Beneficial effects of the traditional medicine Igongsan and its constituent ergosterol on dextran sulfate sodium-induced colitis in mice. | 2015 | Mol Med Rep | pmid:26005209 |
| Liu JY et al. | Mechanisms of azole resistance in Candida albicans clinical isolates from Shanghai, China. | 2015 | Res. Microbiol. | pmid:25748216 |
| Trikka FA et al. | Iterative carotenogenic screens identify combinations of yeast gene deletions that enhance sclareol production. | 2015 | Microb. Cell Fact. | pmid:25903744 |
| Su W et al. | Alleviating Redox Imbalance Enhances 7-Dehydrocholesterol Production in Engineered Saccharomyces cerevisiae. | 2015 | PLoS ONE | pmid:26098102 |
| Monje-Galvan V and Klauda JB | Modeling Yeast Organelle Membranes and How Lipid Diversity Influences Bilayer Properties. | 2015 | Biochemistry | pmid:26497753 |
| Yuan J and Ching CB | Dynamic control of ERG9 expression for improved amorpha-4,11-diene production in Saccharomyces cerevisiae. | 2015 | Microb. Cell Fact. | pmid:25889168 |
| Ottaviano D et al. | Unsaturated fatty acids-dependent linkage between respiration and fermentation revealed by deletion of hypoxic regulatory KlMGA2 gene in the facultative anaerobe-respiratory yeast Kluyveromyces lactis. | 2015 | FEMS Yeast Res. | pmid:26019145 |