Ergosterol

Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Ergosterol?

Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Ergosterol

PubChem Associated disorders and diseases

What pathways are associated with Ergosterol

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Ergosterol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Ergosterol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Ergosterol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Ergosterol?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Ergosterol?

Knock-out

Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Ergosterol

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Authors Title Published Journal PubMed Link
Ferguson GW et al. Voluntary exposure of some western-hemisphere snake and lizard species to ultraviolet-B radiation in the field: how much ultraviolet-B should a lizard or snake receive in captivity? 2010 May-Jun Zoo Biol. pmid:19484753
Song S et al. [Conditions for extraction of ergosterol from fruits of Ganoderma lucidum using supercritical fluid extration]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19894506
He P et al. [Study on chemical constituents in rhizome of Pinellia ternata]. 2005 Zhongguo Zhong Yao Za Zhi pmid:16075730
Yu J et al. [Steroidal constituents from Saussurea gossypiphora D. Don]. 1991 Zhongguo Zhong Yao Za Zhi pmid:1786098
Liu JM et al. [Chemical constituents of Cordyceps mililaris (L.) Link]. 1989 Zhongguo Zhong Yao Za Zhi pmid:2597325
Chao JF et al. [Chemical constituents from branch of Broussonetia papyrifera]. 2006 Zhongguo Zhong Yao Za Zhi pmid:17048607
Li JL et al. [A comparative study on sterols of ethanol extract and water extract from Hericium erinaceus]. 2001 Zhongguo Zhong Yao Za Zhi pmid:12776329
Shen YX et al. [Studies on the chemical constituents of Shiraia bambusicola]. 2002 Zhongguo Zhong Yao Za Zhi pmid:12776569
Xiao SY et al. [Secondary metabolites of Gliocladium sp., a growth accelerating fungus for Anoectochilus roxburghii (Wall.) Lindl]. 2001 Zhongguo Zhong Yao Za Zhi pmid:12528522
Liu C et al. [Studies on chemical constituents from the fruiting bodies of Ganoderma sinense Zhao, Xu et Zhang]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17432147
Cui D et al. [Chemical constituents of Bulgaria inquinans (Fries)]. 1997 Zhongguo Zhong Yao Za Zhi pmid:11038915
Chai H et al. [Constituents from the fruiting body of Ganoderma lucidum (Fr.) Karst]. 1997 Zhongguo Zhong Yao Za Zhi pmid:11038948
Guo S et al. [Determination of sugar components in wild and cultured sclerotia of Grifola umbellata (pers. ex Fr.) Pilat at different ages]. 1992 Zhongguo Zhong Yao Za Zhi pmid:1418531
Song YX et al. [Secondary metabolites of mangrove endophytic fungus BL321 in the South China Sea]. 2010 Zhong Yao Cai pmid:21049610
Xia XK et al. [Study on the second metabolisms from fungus HS-1 Epicoccum spp. from the sea cucumber in Yellow Sea]. 2010 Zhong Yao Cai pmid:21355195
Liu JJ et al. [Determination of ergosterol in Ganoderma lucidum from different varieties and cultured tree species by HPLC]. 2011 Zhong Yao Cai pmid:21823472
Zhang HJ et al. [Studies on chemical constituents of Lobaria kurokawae yoshim]. 2007 Zhong Yao Cai pmid:17918430
Jiang JS et al. [Study on the chemical constituents from Cyathea spinulosa]. 2012 Zhong Yao Cai pmid:23019903
Jia L et al. [Studies on the chemical constituents from petroleum ether portion of Abelmoschus esculentus]. 2010 Zhong Yao Cai pmid:21213539
Gao ZH et al. [Studies on the anti-tumor activity principles of a marine-derived fungus BZYT-21]. 2008 Zhong Yao Cai pmid:19180954
Bi Y et al. [Studies on chemical constituents of mycelium of fungus Cephalosporium sp. AL031(II)]. 2003 Zhong Yao Cai pmid:12858768
Yang RY et al. [Study on the sterols from a brown alga endophytic fungus (NO. ZZF36) from the South China Sea]. 2006 Zhong Yao Cai pmid:17212043
Wu SH et al. [Studies on chemical constituents of Tylopilus plumbeoviolaceus]. 2009 Zhong Yao Cai pmid:19504968
Bi Y et al. [Studies on chemical constituents of mycelium of fungus Cephalosporium sp. AL031(I)]. 2001 Zhong Yao Cai pmid:11715193
Müller HM and Boley A [Effects of autoclaving and surface disinfection of wheat (Triticum aestivum) on the production of ergosterol, ochratoxin A and citrinin by Penicillium verrucosum]. 1991 Zentralbl. Mikrobiol. pmid:1950201
Müller HM and Boley A Studies on the refrigerated storage of wheat (Triticum aestivum). 2. Ergosterol, xanthomegnin, viomellein and brevianamide A after inoculation with Penicillium viridicatum. 1993 Zentralbl. Mikrobiol. pmid:8237145
KEINING E and BRETT R [Not Available]. 1949 Zentralbl Haut Geschlechtskr Grenzgeb pmid:18128414
Liu DZ et al. A new ergostane triterpenoid from a solid culture of the basidiomycete Inocybe lilacina. 2014 Mar-Apr Z. Naturforsch., C, J. Biosci. pmid:24873028
Sabir F et al. In vitro withanolide production by Withania somnifera L. cultures. 2008 May-Jun Z. Naturforsch., C, J. Biosci. pmid:18669028
Tabakova S et al. Anticandidial effect of phenylbutene derivatives and their interaction with ergosterol. 1999 Jan-Feb Z. Naturforsch., C, J. Biosci. pmid:10097407
Shimizu B et al. Phytotoxic components produced by pathogenic Fusarium against morning glory. 2005 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:16402546
Iida M et al. Cellular fatty acids derived from normal alkanes by Candida rugosa. 1980 Z. Allg. Mikrobiol. pmid:7434793
Penman CS and Duffus JH Accumulation of ergosterol during the cell cycle of the budding yeast Kluyveromyces fragilis. 1976 Z. Allg. Mikrobiol. pmid:983132
Müller H and Voigt B [Determination of free and bound ergosterol in microorganisms]. 1984 Z. Allg. Mikrobiol. pmid:6719940
Sarachek A Ergosterol-enhanced recovery of mutagen treated Candida albicans. 1977 Z. Allg. Mikrobiol. pmid:337692
Marisco G et al. Low ergosterol content in yeast adh1 mutant enhances chitin maldistribution and sensitivity to paraquat-induced oxidative stress. 2011 Yeast pmid:21360751
Šimová Z et al. The yeast Saccharomyces cerevisiae Pdr16p restricts changes in ergosterol biosynthesis caused by the presence of azole antifungals. 2013 Yeast pmid:23606207
Ahmad A et al. Antifungal activity of Coriaria nepalensis essential oil by disrupting ergosterol biosynthesis and membrane integrity against Candida. 2011 Yeast pmid:21755533
Lewis TL et al. Pleiotropic mutations in Saccharomyces cerevisiae affecting sterol uptake and metabolism. 1988 Yeast pmid:3059715
Jiang B et al. A new family of yeast genes implicated in ergosterol synthesis is related to the human oxysterol binding protein. 1994 Yeast pmid:8017104
Warringer J and Blomberg A Involvement of yeast YOL151W/GRE2 in ergosterol metabolism. 2006 Yeast pmid:16598690
Rautio JJ et al. Monitoring yeast physiology during very high gravity wort fermentations by frequent analysis of gene expression. 2007 Yeast pmid:17605133
Konecna A et al. ERG6 gene deletion modifies Kluyveromyces lactis susceptibility to various growth inhibitors. 2016 Yeast pmid:27668979
Smith SJ and Parks LW The ERG3 gene in Saccharomyces cerevisiae is required for the utilization of respiratory substrates and in heme-deficient cells. 1993 Yeast pmid:8109167
Arneborg N et al. The effect of ethanol and specific growth rate on the lipid content and composition of Saccharomyces cerevisiae grown anaerobically in a chemostat. 1995 Yeast pmid:8533470
Daum G et al. Systematic analysis of yeast strains with possible defects in lipid metabolism. 1999 Yeast pmid:10341423
Jung WH et al. Deletion of PDE2, the gene encoding the high-affinity cAMP phosphodiesterase, results in changes of the cell wall and membrane in Candida albicans. 2005 Yeast pmid:15789349
Launhardt H et al. Drug-induced phenotypes provide a tool for the functional analysis of yeast genes. 1998 Yeast pmid:9717239
Marcireau C et al. FEN2: a gene implicated in the catabolite repression-mediated regulation of ergosterol biosynthesis in yeast. 1996 Yeast pmid:8771708
Tomeo ME et al. Effect of sterol alterations on conjugation in Saccharomyces cerevisiae. 1992 Yeast pmid:1293881