| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Ergosterol
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|---|---|---|---|---|
| Dai J et al. | Elimination of quiescent slow-cycling cells via reducing quiescence depth by natural compounds purified from Ganoderma lucidum. | 2017 | Oncotarget | pmid:28099150 |
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| Tintino SR et al. | Cholesterol and ergosterol affect the activity of Staphylococcus aureus antibiotic efflux pumps. | 2017 | Microb. Pathog. | pmid:28088472 |
| de Sá NP et al. | Effects of two 6-quinolinyl chalcones on the integrity of plasma membrane of Paracoccidioides brasiliensis. | 2017 | J. Antibiot. | pmid:28074055 |
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| Zhang DH et al. | Overexpression of the homologous lanosterol synthase gene in ganoderic acid biosynthesis in Ganoderma lingzhi. | 2017 | Phytochemistry | pmid:27894599 |
| Ono J et al. | Widespread Genetic Incompatibilities between First-Step Mutations during Parallel Adaptation of Saccharomyces cerevisiae to a Common Environment. | 2017 | PLoS Biol. | pmid:28114370 |
| Manik MK et al. | Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction. | 2017 | Structure | pmid:28319008 |
| Favarin BZ et al. | Effect of the presence of cholesterol in the interfacial microenvironment on the modulation of the alkaline phosphatase activity during in vitro mineralization. | 2017 | Colloids Surf B Biointerfaces | pmid:28472750 |
| Sardi JC et al. | Unexplored endemic fruit species from Brazil: Antibiofilm properties, insights into mode of action, and systemic toxicity of four Eugenia spp. | 2017 | Microb. Pathog. | pmid:28259673 |
| Peixoto LR et al. | Antifungal activity, mode of action and anti-biofilm effects of Laurus nobilis Linnaeus essential oil against Candida spp. | 2017 | Arch. Oral Biol. | pmid:27771586 |
| Gao Y et al. | In Vitro and In Vivo Activity of Fomitopsis Pinicola (Sw. Ex Fr.) Karst Chloroform (Fpkc) Extract Against S180 Tumor Cells. | 2017 | Cell. Physiol. Biochem. | pmid:29241162 |
| Miller MB et al. | 24-Methylenecyclopropane steroidal inhibitors: A Trojan horse in ergosterol biosynthesis that prevents growth of Trypanosoma brucei. | 2017 | Biochim. Biophys. Acta | pmid:27939999 |
| Mwenechanya R et al. | Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana. | 2017 | PLoS Negl Trop Dis | pmid:28622334 |
| Ruan R et al. | Functional analysis of two sterol regulatory element binding proteins in Penicillium digitatum. | 2017 | PLoS ONE | pmid:28467453 |
| Krogerus K et al. | Inheritance of brewing-relevant phenotypes in constructed Saccharomyces cerevisiae × Saccharomyces eubayanus hybrids. | 2017 | Microb. Cell Fact. | pmid:28431563 |
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| Lin M et al. | Ergosteryl 2-naphthoate, An Ergosterol Derivative, Exhibits Antidepressant Effects Mediated by the Modification of GABAergic and Glutamatergic Systems. | 2017 | Molecules | pmid:28362353 |
| Karaca Gençer H et al. | New Benzimidazole-1,2,4-Triazole Hybrid Compounds: Synthesis, Anticandidal Activity and Cytotoxicity Evaluation. | 2017 | Molecules | pmid:28346364 |
| Kamthan A et al. | Expression of C-5 sterol desaturase from an edible mushroom in fisson yeast enhances its ethanol and thermotolerance. | 2017 | PLoS ONE | pmid:28278249 |
| Iaea DB et al. | Role of STARD4 in sterol transport between the endocytic recycling compartment and the plasma membrane. | 2017 | Mol. Biol. Cell | pmid:28209730 |
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| Zhang HY et al. | Ergosterol-loaded poly(lactide-co-glycolide) nanoparticles with enhanced in vitro antitumor activity and oral bioavailability. | 2016 | Acta Pharmacol. Sin. | pmid:27133301 |
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