| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mitropoulos KA et al. | Lanosterol 14alpha-demethylase. Similarity of the enzyme system from yeast and rat liver. | 1976 | Steroids | pmid:781918 |
| Poklepovich TJ et al. | The cytochrome b5 dependent C-5(6) sterol desaturase DES5A from the endoplasmic reticulum of Tetrahymena thermophila complements ergosterol biosynthesis mutants in Saccharomyces cerevisiae. | 2012 | Steroids | pmid:22982564 |
| Jinming G et al. | A novel sterol from Chinese truffles Tuber indicum. | 2001 | Steroids | pmid:11522340 |
| Piatak DM and Swenson RP | Selective oxidation of the double bonds in the 4-phenyl-1,2,4-triazoline-3,5-dione diels-alder adduct of ergosterol acetate. | 1984 | Steroids | pmid:6523535 |
| Müller C et al. | A convenient cellular assay for the identification of the molecular target of ergosterol biosynthesis inhibitors and quantification of their effects on total ergosterol biosynthesis. | 2013 | Steroids | pmid:23454215 |
| Hu JF et al. | 26-Nor-25-isopropyl-ergosta-5,7,22E-trien-3beta-ol: a new C(29) sterol from the sponge Agelas sceptrum from Jamaica. | 2002 | Steroids | pmid:12123785 |
| Sonego JM et al. | Synthesis and antifungal activity of C-21 steroids with an aromatic D ring. | 2013 | Steroids | pmid:23499954 |
| Jeong TM et al. | Sterols from a species of Pichia, a n-alkane-utilizing yeast. | 1975 | Steroids | pmid:1154452 |
| Morisaki M et al. | Nutritional effect of possible intermediates of phytosterol dealkylation in the silkworm, Bombyx mori. | 1974 | Steroids | pmid:4421556 |
| Zhang BB et al. | Cytotoxic cholestane-type and ergostane-type steroids from the aerial parts of Euphorbia altotibetic. | 2013 | Steroids | pmid:23131765 |
| Wang F et al. | Six new ergosterols from the marine-derived fungus Rhizopus sp. | 2008 | Steroids | pmid:17900642 |
| Gebreyesus T et al. | Minor and trace sterols in marine invertebrates 55. The isolation, structure elucidation and synthesis of ergosta-5, 24(28), 25-trien-3 beta-ol. | 1985 | Steroids | pmid:2871644 |
| Harki E et al. | Identification and quantification of Tuber melanosporum Vitt. sterols. | 1996 | Steroids | pmid:8910974 |
| Misra L et al. | Selective reactivity of 2-mercaptoethanol with 5beta,6beta-epoxide in steroids from Withania somnifera. | 2008 | Steroids | pmid:18061225 |
| Mehdi H et al. | Sterols of Acanthamoeba culbertsoni strain A-1. | 1988 May-Jun | Steroids | pmid:3242176 |
| Iguchi K et al. | A new 5 alpha,8 alpha-epidioxy sterol from the Okinawan marine sponge of the Axinyssa genus. | 1993 | Steroids | pmid:8236326 |
| Malik S and Djerassi C | Minor and trace sterols in marine invertebrates. 61. Isolation and structure elucidation of new A-nor sterols from the marine sponge Phakellia aruensis. | 1989 Mar-May | Steroids | pmid:2799846 |
| Mercer EI et al. | Effect of some sterol-biosynthesis-inhibiting fungicides on the biosynthesis of polyisoprenoid compounds in barley seedings. | 1989 Mar-May | Steroids | pmid:2799851 |
| Ambrus G et al. | Novel 26-oxygenated products in microbial degradation of ergosterol. | 1995 | Steroids | pmid:8545852 |
| Dovbnya DV et al. | Microbial side-chain degradation of ergosterol and its 3-substituted derivatives: a new route for obtaining of deltanoids. | 2010 | Steroids | pmid:20385161 |