| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Blume T et al. | Two syntheses of FF-MAS. | 2003 | Org. Lett. | pmid:12762665 |
| Lemriss S et al. | Screening of nonpolyenic antifungal metabolites produced by clinical isolates of actinomycetes. | 2003 | Can. J. Microbiol. | pmid:14735216 |
| Kaur P et al. | Effect of 1-oxo-5beta, 6beta-epoxy-witha-2-ene-27-ethoxy-olide isolated from the roots of Withania somnifera on stress indices in Wistar rats. | 2003 | J Altern Complement Med | pmid:14736361 |
| O'Keeffe J et al. | Exposure of the yeast Candida albicans to the anti-neoplastic agent adriamycin increases the tolerance to amphotericin B. | 2003 | J. Pharm. Pharmacol. | pmid:14738588 |
| Gomès E et al. | Nonspecific lipid-transfer protein genes expression in grape (Vitis sp.) cells in response to fungal elicitor treatments. | 2003 | Mol. Plant Microbe Interact. | pmid:12744517 |
| Duport C et al. | Critical role of the plasma membrane for expression of mammalian mitochondrial side chain cleavage activity in yeast. | 2003 | Eur. J. Biochem. | pmid:12654006 |
| Rossard S et al. | Characterization of sterol uptake in leaf tissues of sugar beet. | 2003 | Planta | pmid:12920595 |
| Onda M et al. | Susceptibilities of phospholipid vesicles containing different sterols to amphotericin B-loaded lysophosphatidylcholine micelles. | 2003 | J. Biochem. | pmid:12944378 |
| Noda H and Koizumi Y | Sterol biosynthesis by symbiotes: cytochrome P450 sterol C-22 desaturase genes from yeastlike symbiotes of rice planthoppers and anobiid beetles. | 2003 | Insect Biochem. Mol. Biol. | pmid:12770582 |
| Onyewu C et al. | Ergosterol biosynthesis inhibitors become fungicidal when combined with calcineurin inhibitors against Candida albicans, Candida glabrata, and Candida krusei. | 2003 | Antimicrob. Agents Chemother. | pmid:12604527 |
| Atshaves BP et al. | Sterol carrier protein-2 selectively alters lipid composition and cholesterol dynamics of caveolae/lipid raft vs nonraft domains in L-cell fibroblast plasma membranes. | 2003 | Biochemistry | pmid:14661971 |
| Gössnitzer E et al. | Novel high energy intermediate analogues with triazasterol-related structures as inhibitors of ergosterol biosynthesis. III. Synthesis and antifungal activity of N4-alkyl-1,6,7,11b-tetrahydro-2H-pyrimido[4,3-a]isoquinolin-4-amine salts. | 2003 | Eur J Pharm Sci | pmid:12791418 |
| KlobucnÃková V et al. | Terbinafine resistance in a pleiotropic yeast mutant is caused by a single point mutation in the ERG1 gene. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12963042 |
| Nicol RW et al. | Ginsenosides stimulate the growth of soilborne pathogens of American ginseng. | 2003 | Phytochemistry | pmid:12946424 |
| Gössnitzer E et al. | Novel high energy intermediate analogues with a triazasterol structure as potential ergosterol biosynthesis inhibitors IV: antimicrobial activity of mono-, bi-, and tricyclic 8, 13, 15-triazasteroid analogues including the synthesis of novel 4-alkylamino- and 4-alkenylamino-9-hydroxypyrimidoisoquinolines. | 2003 | Arch. Pharm. (Weinheim) | pmid:12953221 |
| Matheson MC et al. | Residential characteristics predict changes in Der p 1, Fel d 1 and ergosterol but not fungi over time. | 2003 | Clin. Exp. Allergy | pmid:12956751 |
| Thevissen K et al. | DmAMP1, an antifungal plant defensin from dahlia (Dahlia merckii), interacts with sphingolipids from Saccharomyces cerevisiae. | 2003 | FEMS Microbiol. Lett. | pmid:13129623 |
| Söderström C et al. | Use of an electronic tongue to analyze mold growth in liquid media. | 2003 | Int. J. Food Microbiol. | pmid:12745231 |
| Lübbehüsen TL et al. | Morphology and physiology of the dimorphic fungus Mucor circinelloides (syn. M. racemosus) during anaerobic growth. | 2003 | Mycol. Res. | pmid:12747334 |
| Subbiah MT and Abplanalp W | Ergosterol (major sterol of baker's and brewer's yeast extracts) inhibits the growth of human breast cancer cells in vitro and the potential role of its oxidation products. | 2003 | Int J Vitam Nutr Res | pmid:12690907 |
| Fornairon-Bonnefond C and Salmon JM | Impact of oxygen consumption by yeast lees on the autolysis phenomenon during simulation of wine aging on lees. | 2003 | J. Agric. Food Chem. | pmid:12696941 |
| Bahmed K et al. | Relation between cell wall chitin content and susceptibility to amphotericin B in Kluyveromyces, Candida and Schizosaccharomyces species. | 2003 | Res. Microbiol. | pmid:12706511 |
| Gudheti MV et al. | Interaction of apolipoprotein A-I with lecithin-cholesterol vesicles in the presence of phospholipase C. | 2003 | Biochim. Biophys. Acta | pmid:14729075 |
| Landry J and Sternglanz R | Yeast Fms1 is a FAD-utilizing polyamine oxidase. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12670477 |
| Dahlman L et al. | Carbon and nitrogen distribution in the green algal lichens Hypogymnia physodes and Platismatia glauca in relation to nutrient supply. | 2003 | Planta | pmid:12721847 |
| Bracher F | [Attack point of ergosterol biosynthesis. Drugs and pharmacology]. | 2003 | Pharm Unserer Zeit | pmid:12677964 |
| Maebashi K et al. | Proliferation of intracellular structure corresponding to reduced affinity of fluconazole for cytochrome P-450 in two low-susceptibility strains of Candida albicans isolated from a Japanese AIDS patient. | 2003 | Microbiol. Immunol. | pmid:12680714 |
| Hand RA et al. | Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor. | 2003 | Eukaryotic Cell | pmid:12684380 |
| Liebich J et al. | Structural and functional approach to studying pesticide side-effects on specific soil functions. | 2003 | Environ. Toxicol. Chem. | pmid:12685713 |
| Nikolcheva LG et al. | Determining diversity of freshwater fungi on decaying leaves: comparison of traditional and molecular approaches. | 2003 | Appl. Environ. Microbiol. | pmid:12732520 |
| Gu JQ et al. | Minor withanolides from Physalis philadelphica: structures, quinone reductase induction activities, and liquid chromatography (LC)-MS-MS investigation as artifacts. | 2003 | Chem. Pharm. Bull. | pmid:12736452 |
| Urbina JA et al. | Mechanism of action of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the causative agent of Chagas' disease. | 2003 | Antimicrob. Agents Chemother. | pmid:12760897 |
| Avrahami D and Shai Y | Bestowing antifungal and antibacterial activities by lipophilic acid conjugation to D,L-amino acid-containing antimicrobial peptides: a plausible mode of action. | 2003 | Biochemistry | pmid:14674771 |
| Krska R et al. | Zearalenone in maize: stability testing and matrix characterisation of a certified reference material. | 2003 | Food Addit Contam | pmid:14726278 |
| Rahman A et al. | Argyroside from Argyreia nervosa seeds. | 2003 | Pharmazie | pmid:12622256 |
| Rosenfeld E et al. | Oxygen consumption by anaerobic Saccharomyces cerevisiae under enological conditions: effect on fermentation kinetics. | 2003 | Appl. Environ. Microbiol. | pmid:12513985 |
| Loeffler J and Stevens DA | Antifungal drug resistance. | 2003 | Clin. Infect. Dis. | pmid:12516028 |
| McIntosh AL et al. | Fluorescence and multiphoton imaging resolve unique structural forms of sterol in membranes of living cells. | 2003 | J. Biol. Chem. | pmid:12456684 |
| Yang LY et al. | H1-A extracted from Cordyceps sinensis suppresses the proliferation of human mesangial cells and promotes apoptosis, probably by inhibiting the tyrosine phosphorylation of Bcl-2 and Bcl-XL. | 2003 | J. Lab. Clin. Med. | pmid:12518171 |
| Zhao H et al. | Definitive structural identities of Pneumocystis jirovecii sterols. | 2003 | J. Eukaryot. Microbiol. | pmid:14736217 |
| Amborabé BE et al. | Specific perception of ergosterol by plant cells. | 2003 | C. R. Biol. | pmid:12876888 |
| Sanglard D et al. | Candida albicans mutations in the ergosterol biosynthetic pathway and resistance to several antifungal agents. | 2003 | Antimicrob. Agents Chemother. | pmid:12878497 |
| He X et al. | Overexpression of a sterol C-24(28) reductase increases ergosterol production in Saccharomyces cerevisiae. | 2003 | Biotechnol. Lett. | pmid:12882006 |
| Young LY et al. | Disruption of ergosterol biosynthesis confers resistance to amphotericin B in Candida lusitaniae. | 2003 | Antimicrob. Agents Chemother. | pmid:12936965 |
| Sardari S et al. | Modulatory effect of cAMP on fungal ergosterol level and inhibitory activity of azole drugs. | 2003 | Can. J. Microbiol. | pmid:12897828 |
| Hietala AM et al. | Multiplex real-time PCR for monitoring Heterobasidion annosum colonization in Norway spruce clones that differ in disease resistance. | 2003 | Appl. Environ. Microbiol. | pmid:12902224 |
| Higgins VJ et al. | Yeast genome-wide expression analysis identifies a strong ergosterol and oxidative stress response during the initial stages of an industrial lager fermentation. | 2003 | Appl. Environ. Microbiol. | pmid:12902271 |
| Bi Y et al. | [Studies on chemical constituents of mycelium of fungus Cephalosporium sp. AL031(II)]. | 2003 | Zhong Yao Cai | pmid:12858768 |
| Veen M et al. | Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. | 2003 | FEMS Yeast Res. | pmid:14554200 |
| Murtoniemi T et al. | Effect of plasterboard composition on Stachybotrys chartarum growth and biological activity of spores. | 2003 | Appl. Environ. Microbiol. | pmid:12839740 |
| Reeslev M et al. | Quantifying mold biomass on gypsum board: comparison of ergosterol and beta-N-acetylhexosaminidase as mold biomass parameters. | 2003 | Appl. Environ. Microbiol. | pmid:12839773 |
| Uma Devi P and Kamath R | Radiosensitizing effect of withaferin A combined with hyperthermia on mouse fibrosarcoma and melanoma. | 2003 | J. Radiat. Res. | pmid:12841592 |
| Kaneko E et al. | Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist. | 2003 | J. Biol. Chem. | pmid:12847102 |
| Kuo YC et al. | Activation and proliferation signals in primary human T lymphocytes inhibited by ergosterol peroxide isolated from Cordyceps cicadae. | 2003 | Br. J. Pharmacol. | pmid:14504132 |
| Jayaprakasam B et al. | Growth inhibition of human tumor cell lines by withanolides from Withania somnifera leaves. | 2003 | Life Sci. | pmid:14575818 |
| Nicotra VE et al. | 15,21-Cyclowithanolides from Jaborosa bergii. | 2003 | J. Nat. Prod. | pmid:14640521 |
| Song JL et al. | Antifungal activity of fluconazole in combination with lovastatin and their effects on gene expression in the ergosterol and prenylation pathways in Candida albicans. | 2003 | Med. Mycol. | pmid:14653518 |
| Corente Ch and Knülle W | Trophic determinants of hypopus induction in the stored-product mite Lepidoglyphus destructor (Acari: Astigmata). | 2003 | Exp. Appl. Acarol. | pmid:14580061 |
| Puglisi E et al. | Cholesterol, beta-sitosterol, ergosterol, and coprostanol in agricultural soils. | 2003 Mar-Apr | J. Environ. Qual. | pmid:12708669 |
| Zheng SZ et al. | Two new polyporusterones from Polyorus umbellatus. | 2004 | Nat. Prod. Res. | pmid:15248606 |
| Wady L et al. | Heterogeneity in microbial exposure in schools in Sweden, Poland and Jordan revealed by analysis of chemical markers. | 2004 | J Expo Anal Environ Epidemiol | pmid:15254476 |
| Pietri A et al. | Occurrence of mycotoxins and ergosterol in maize harvested over 5 years in Northern Italy. | 2004 | Food Addit Contam | pmid:15204549 |
| Eshwika A et al. | Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to amphotericin B and miconazole. | 2004 | Biometals | pmid:15259362 |
| Veras ML et al. | Cytotoxic epimeric withaphysalins from leaves of Acnistus arborescens. | 2004 | Planta Med. | pmid:15241891 |
| Parveen M et al. | Response of Saccharomyces cerevisiae to a monoterpene: evaluation of antifungal potential by DNA microarray analysis. | 2004 | J. Antimicrob. Chemother. | pmid:15201226 |
| Barker KS et al. | Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans. | 2004 | J. Antimicrob. Chemother. | pmid:15201233 |
| Sorger D et al. | A yeast strain lacking lipid particles bears a defect in ergosterol formation. | 2004 | J. Biol. Chem. | pmid:15155725 |
| Matsumori N et al. | An amphotericin B-ergosterol covalent conjugate with powerful membrane permeabilizing activity. | 2004 | Chem. Biol. | pmid:15157878 |
| Veras ML et al. | Cytotoxic withaphysalins from the leaves of Acnistus arborescens. | 2004 | J. Nat. Prod. | pmid:15104512 |
| Cheng CS et al. | Binding mechanism of nonspecific lipid transfer proteins and their role in plant defense. | 2004 | Biochemistry | pmid:15504025 |
| Mukhopadhyay K et al. | Membrane sphingolipid-ergosterol interactions are important determinants of multidrug resistance in Candida albicans. | 2004 | Antimicrob. Agents Chemother. | pmid:15105135 |
| Fujimoto H et al. | Six immunosuppressive features from an ascomycete, Zopfiella longicaudata, found in a screening study monitored by immunomodulatory activity. | 2004 | Chem. Pharm. Bull. | pmid:15305003 |
| Bruckmann A et al. | Regulation of transcription by Saccharomyces cerevisiae 14-3-3 proteins. | 2004 | Biochem. J. | pmid:15142031 |
| Li SP et al. | Simultaneous determination of ergosterol, nucleosides and their bases from natural and cultured Cordyceps by pressurised liquid extraction and high-performance liquid chromatography. | 2004 | J Chromatogr A | pmid:15146928 |
| Li P et al. | [Simultaneous determination of ergosterol, nucleosides and their bases from natural and cultured Cordyceps by pressurized solvent extraction and high performance liquid chromatography]. | 2004 | Yao Xue Xue Bao | pmid:15696933 |
| Markkola A et al. | Defoliation increases carbon limitation in ectomycorrhizal symbiosis of Betula pubescens. | 2004 | Oecologia | pmid:15148601 |
| Bado S et al. | Lethal and sublethal effects of withanolides from Salpichroa origanifolia and analogues on Ceratitis capitata. | 2004 | J. Agric. Food Chem. | pmid:15137828 |
| Shen YC et al. | Evaluation of the anti-inflammatory activity of zhankuic acids isolated from the fruiting bodies of Antrodia camphorata. | 2004 | Planta Med. | pmid:15095145 |
| Chmel' IaV et al. | [Screening of natural compounds with hypolipidemic activity]. | 2004 | Antibiot. Khimioter. | pmid:15727139 |
| Wüstner D et al. | Different transport routes for high density lipoprotein and its associated free sterol in polarized hepatic cells. | 2004 | J. Lipid Res. | pmid:14679167 |
| Favre B et al. | Biochemical characterization of terbinafine-resistant Trichophyton rubrum isolates. | 2004 | Med. Mycol. | pmid:15682641 |
| Fan N et al. | [Enhanced ergosterol production by recombinant Saccharomyces cerevisiae 1190 harboring Vitreoscilla hemoglobin gene (vgb)]. | 2004 | Sheng Wu Gong Cheng Xue Bao | pmid:15971621 |
| MacKenzie SE et al. | Isolation of sterols from the marine fungus Corollospora lacera. | 2004 | Can. J. Microbiol. | pmid:15714238 |
| Mongrand S et al. | Lipid rafts in higher plant cells: purification and characterization of Triton X-100-insoluble microdomains from tobacco plasma membrane. | 2004 | J. Biol. Chem. | pmid:15190066 |
| Vanden Bossche H et al. | The novel azole R126638 is a selective inhibitor of ergosterol synthesis in Candida albicans, Trichophyton spp., and Microsporum canis. | 2004 | Antimicrob. Agents Chemother. | pmid:15328084 |
| Micelli S et al. | Effect of sterols on beta-amyloid peptide (AbetaP 1-40) channel formation and their properties in planar lipid membranes. | 2004 | Biophys. J. | pmid:15041662 |
| Liu JY et al. | Aspergillus fumigatus CY018, an endophytic fungus in Cynodon dactylon as a versatile producer of new and bioactive metabolites. | 2004 | J. Biotechnol. | pmid:15522437 |
| Coutinho A et al. | Cholesterol and ergosterol influence nystatin surface aggregation: relation to pore formation. | 2004 | Biophys. J. | pmid:15315952 |
| Hao M et al. | Effects of cholesterol depletion and increased lipid unsaturation on the properties of endocytic membranes. | 2004 | J. Biol. Chem. | pmid:14734557 |
| Riaz N et al. | Cholinesterase-inhibiting withanolides from Ajuga bracteosa. | 2004 | Chem. Biodivers. | pmid:17191906 |
| Edqvist J et al. | Plants express a lipid transfer protein with high similarity to mammalian sterol carrier protein-2. | 2004 | J. Biol. Chem. | pmid:15456765 |
| Tedrick K et al. | Enhanced membrane fusion in sterol-enriched vacuoles bypasses the Vrp1p requirement. | 2004 | Mol. Biol. Cell | pmid:15254266 |
| Soubias O et al. | Understanding sterol-membrane interactions, part II: complete 1H and 13C assignments by solid-state NMR spectroscopy and determination of the hydrogen-bonding partners of cholesterol in a lipid bilayer. | 2004 | Chemistry | pmid:15497136 |
| Karst F et al. | Farnesyl diphosphate synthase activity affects ergosterol level and proliferation of yeast Saccharomyces cerevisae. | 2004 | Cell Biol. Int. | pmid:14984745 |
| Song JL et al. | The Candida albicans lanosterol 14-alpha-demethylase (ERG11) gene promoter is maximally induced after prolonged growth with antifungal drugs. | 2004 | Antimicrob. Agents Chemother. | pmid:15047513 |
| Gallegos AM et al. | Structure and cholesterol domain dynamics of an enriched caveolae/raft isolate. | 2004 | Biochem. J. | pmid:15149285 |
| Bibikova MV et al. | [Lovastatin effect on ergosterol production and growth of Tolypocladium inflatum 106]. | 2004 | Antibiot. Khimioter. | pmid:15460015 |
| Mo C et al. | The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). | 2004 | Biochim. Biophys. Acta | pmid:15522820 |
| Kadakal C and Artik N | A new quality parameter in tomato and tomato products: ergosterol. | 2004 | Crit Rev Food Sci Nutr | pmid:15540647 |
| Nöllmann M et al. | The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin. | 2004 | Biophys. J. | pmid:15111427 |