| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Regerat F et al. | [Presence of ergosterol and portensterol in mycelial cultures of Tricholoma portentosum and Rhodopaxillus nudus]. | 1976 Sep-Oct | Ann Pharm Fr | pmid:1035071 |
| Sekiya T et al. | Effects of lipid-phase separation on the filipin action on membranes of ergosterol-replaced Tetrahymena cells, as studied by freeze-fracture electron microscopy. | 1979 | Biochim. Biophys. Acta | pmid:103584 |
| Bailly JD et al. | Evaluation of a fluorodensitometric method for analysis of ergosterol as a fungal marker in compound feeds. | 1999 | J. Food Prot. | pmid:10382663 |
| Park KS et al. | Differential inhibitory effects of protoberberines on sterol and chitin biosyntheses in Candida albicans. | 1999 | J. Antimicrob. Chemother. | pmid:10382888 |
| Piecková E and Jesenská Z | Microscopic fungi in dwellings and their health implications in humans. | 1999 | Ann Agric Environ Med | pmid:10384209 |
| Lin CY et al. | Inhibition of activated human mesangial cell proliferation by the natural product of Cordyceps sinensis (H1-A): an implication for treatment of IgA mesangial nephropathy. | 1999 | J. Lab. Clin. Med. | pmid:10385482 |
| Boissy G et al. | The 2.1 A structure of an elicitin-ergosterol complex: a recent addition to the Sterol Carrier Protein family. | 1999 | Protein Sci. | pmid:10386869 |
| Siau H and Kerridge D | 5-Fluorocytosine antagonizes the action of sterol biosynthesis inhibitors in Candida glabrata. | 1999 | J. Antimicrob. Chemother. | pmid:10404315 |
| Vauthrin S et al. | Elicitins trap and transfer sterols from micelles, liposomes and plant plasma membranes. | 1999 | Biochim. Biophys. Acta | pmid:10407084 |
| Wrenn SP et al. | A fluorescence energy transfer study of lecithin-cholesterol vesicles in the presence of phospholipase C. | 1999 | J. Lipid Res. | pmid:10428985 |