| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shimonaka H et al. | Altered microviscosity of in vivo lipid-manipulated membranes in Tetrahymena pyriformis: a fluorescence study. | 1978 | Experientia | pmid:95966 |
| Sajbidor J et al. | Influence of new fenpropimorph fungicides on the growth and sterol composition in Saccharomyces cerevisiae: relationship between structure and activity. | 1998 | J. Pharm. Pharmacol. | pmid:9600722 |
| Sugawara T et al. | YM-170320, a novel lipopeptide antibiotic inducing morphological change of colonies in a mutant of Candida tropicalis pK233. | 1998 | J. Antibiot. | pmid:9630867 |
| Atta-ur-Rahman A et al. | Two new ergostane-type steroidal lactones from Withania coagulans. | 1998 | J. Nat. Prod. | pmid:9644072 |
| Vazquez JA et al. | Stable phenotypic resistance of Candida species to amphotericin B conferred by preexposure to subinhibitory levels of azoles. | 1998 | J. Clin. Microbiol. | pmid:9705415 |
| Tejada-Simon MV and Pestka JJ | Production of polyclonal antibody against ergosterol hemisuccinate using Freund's and Titermax adjuvants. | 1998 | J. Food Prot. | pmid:9713773 |
| Launhardt H et al. | Drug-induced phenotypes provide a tool for the functional analysis of yeast genes. | 1998 | Yeast | pmid:9717239 |
| Wang MM et al. | Role of the sterol superlattice in the partitioning of the antifungal drug nystatin into lipid membranes. | 1998 | Biochemistry | pmid:9718302 |
| Crowley JH et al. | A calcium-dependent ergosterol mutant of Saccharomyces cerevisiae. | 1998 | Curr. Genet. | pmid:9724410 |
| Urbina JA et al. | A carbon-13 nuclear magnetic resonance spectroscopic study of inter-proton pair order parameters: a new approach to study order and dynamics in phospholipid membrane systems. | 1998 | Biophys. J. | pmid:9726938 |
| Fournier I et al. | The structuring effects of amphotericin B on pure and ergosterol- or cholesterol-containing dipalmitoylphosphatidylcholine bilayers: a differential scanning calorimetry study. | 1998 | Biochim. Biophys. Acta | pmid:9733926 |
| De Lucca AJ et al. | Fungicidal properties, sterol binding, and proteolytic resistance of the synthetic peptide D4E1. | 1998 | Can. J. Microbiol. | pmid:9734302 |
| Mukherjee S et al. | Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog. | 1998 | Biophys. J. | pmid:9746532 |
| Marr KA et al. | Rapid, transient fluconazole resistance in Candida albicans is associated with increased mRNA levels of CDR. | 1998 | Antimicrob. Agents Chemother. | pmid:9756759 |
| Orozco AS et al. | Mechanism of fluconazole resistance in Candida krusei. | 1998 | Antimicrob. Agents Chemother. | pmid:9756770 |
| Luo H et al. | Study on kinetics of ergosterol fermentation. | 1998 | Chin. J. Biotechnol. | pmid:9759546 |
| Cotero BV et al. | On the role of sterol in the formation of the amphotericin B channel. | 1998 | Biochim. Biophys. Acta | pmid:9767100 |
| Navashin PS | [Antifungal chemotherapy. Progress and problems]. | 1998 | Antibiot. Khimioter. | pmid:9777098 |
| Togashi H et al. | 4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-alpha activity and the growth of human cancer cells in vitro. | 1998 | Biochem. Pharmacol. | pmid:9783727 |
| Wangspa R and Takemoto JY | Role of ergosterol in growth inhibition of Saccharomyces cerevisiae by syringomycin E. | 1998 | FEMS Microbiol. Lett. | pmid:9809422 |
| Honda M et al. | Accurate detection of Smith-Lemli-Opitz syndrome carriers by measurement of the rate of reduction of the ergosterol C-7 double bond in cultured skin fibroblasts. | 1998 | J. Inherit. Metab. Dis. | pmid:9819706 |
| Penman CS and Duffus JH | Accumulation of ergosterol during the cell cycle of the budding yeast Kluyveromyces fragilis. | 1976 | Z. Allg. Mikrobiol. | pmid:983132 |
| Disch A and Rohmer M | On the absence of the glyceraldehyde 3-phosphate/pyruvate pathway for isoprenoid biosynthesis in fungi and yeasts. | 1998 | FEMS Microbiol. Lett. | pmid:9835029 |
| Swan TM and Watson K | Stress tolerance in a yeast sterol auxotroph: role of ergosterol, heat shock proteins and trehalose. | 1998 | FEMS Microbiol. Lett. | pmid:9851052 |
| el-Mekkawy S et al. | Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. | 1998 | Phytochemistry | pmid:9862140 |
| Qian H and Sheng M | Simultaneous determination of fat-soluble vitamins A, D and E and pro-vitamin D2 in animal feeds by one-step extraction and high-performance liquid chromatography analysis. | 1998 | J Chromatogr A | pmid:9867394 |
| Sandhoff R et al. | Determination of cholesterol at the low picomole level by nano-electrospray ionization tandem mass spectrometry. | 1999 | J. Lipid Res. | pmid:9869658 |
| Woodbury DJ | Nystatin/ergosterol method for reconstituting ion channels into planar lipid bilayers. | 1999 | Meth. Enzymol. | pmid:9916236 |
| Denter J et al. | Changes in the contents of fat-soluble vitamins and provitamins during tempe fermentation. | 1998 | Int. J. Food Microbiol. | pmid:9924943 |
| Abramson D et al. | Relationships among deoxynivalenol, ergosterol and Fusarium exoantigens in Canadian hard and soft wheat. | 1998 | Int. J. Food Microbiol. | pmid:9926999 |
| Beuchet P et al. | Synthesis of 6(alpha, beta)-aminocholestanols as ergosterol biosynthesis inhibitors. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9934483 |
| Ronis MJ et al. | Cytochrome P450 enzymes in the kidney of the bobwhite quail (Colinus virginianus): induction and inhibition by ergosterol biosynthesis inhibiting fungicides. | 1998 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:9972464 |
| Regerat F et al. | [Investigation on ergosterol occurence in fruit bodies of some macromycetes]. | 1976 May-Jun | Ann Pharm Fr | pmid:999160 |