| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Leishmaniasis | D007896 | 19 associated lipids |
| Tinea | D014005 | 5 associated lipids |
| Mycoses | D009181 | 18 associated lipids |
Total
4
Ergosterol
Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Ergosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Ergosterol?
Ergosterol is suspected in Infection, Mycoses, Candidiasis, Chagas Disease, Cyst, Dermatophytosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Ergosterol
PubChem Associated disorders and diseases
What pathways are associated with Ergosterol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Ergosterol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Ergosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Ergosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Ergosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Ergosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Ergosterol?
Knock-out
Knock-out are used in the study 'Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts.' (Pasrija R et al., 2008) and Knock-out are used in the study 'UPC2A is required for high-level azole antifungal resistance in Candida glabrata.' (Whaley SG et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Ergosterol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhang B et al. | Construction of high ergosterol-producing yeast strains and study on the optimal conditions for culture. | 1999 | Chin. J. Biotechnol. | pmid:10668134 |
| Zweytick D et al. | Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae. | 2000 | Eur. J. Biochem. | pmid:10672016 |
| Hing AW et al. | Deuterium NMR investigation of an amphotericin B derivative in mechanically aligned lipid bilayers. | 2000 | Biochim. Biophys. Acta | pmid:10675510 |
| Sridhar KR and Bärlocher F | Initial colonization, nutrient supply, and fungal activity on leaves decaying in streams. | 2000 | Appl. Environ. Microbiol. | pmid:10698779 |
| Hori K et al. | Structure-activity relationships of a new antifungal imidazole, AFK-108, and related compounds. | 2000 | Chem. Pharm. Bull. | pmid:10705477 |
| Kim DS et al. | Aromatase and sulfatase inhibitors from Lepiota americana. | 2000 | Planta Med. | pmid:10705743 |
| Parks LW et al. | Use of sterol mutants as probes for sterol functions in the yeast, Saccharomyces cerevisiae. | 1999 | Crit. Rev. Biochem. Mol. Biol. | pmid:10711784 |
| Böcking T et al. | Effects of singlet oxygen on membrane sterols in the yeast Saccharomyces cerevisiae. | 2000 | Eur. J. Biochem. | pmid:10712590 |
| Bagnat M et al. | Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10716729 |
| Linck LM et al. | Fetal demise with Smith-Lemli-Opitz syndrome confirmed by tissue sterol analysis and the absence of measurable 7-dehydrocholesterol Delta(7)-reductase activity in chorionic villi. | 2000 | Prenat. Diagn. | pmid:10719329 |
| Nose H et al. | PF1163A and B, new antifungal antibiotics produced by Penicillium sp. I. Taxonomy of producing strain, fermentation, isolation and biological activities. | 2000 | J. Antibiot. | pmid:10724005 |
| de Sio F et al. | Analysis of free and esterified ergosterol in tomato products. | 2000 | J. Agric. Food Chem. | pmid:10725149 |
| Gallegos AM et al. | A potential role for sterol carrier protein-2 in cholesterol transfer to mitochondria. | 2000 | Chem. Phys. Lipids | pmid:10727111 |
| Löffler J et al. | Phospholipid and sterol analysis of plasma membranes of azole-resistant Candida albicans strains. | 2000 | FEMS Microbiol. Lett. | pmid:10731607 |
| Soustre I et al. | Sterol metabolism and ERG2 gene regulation in the yeast Saccharomyces cerevisiae. | 2000 | FEBS Lett. | pmid:10734216 |
| Inoue T et al. | Cloning and characterization of a gene complementing the mutation of an ethanol-sensitive mutant of sake yeast. | 2000 | Biosci. Biotechnol. Biochem. | pmid:10737174 |
| Bammert GF and Fostel JM | Genome-wide expression patterns in Saccharomyces cerevisiae: comparison of drug treatments and genetic alterations affecting biosynthesis of ergosterol. | 2000 | Antimicrob. Agents Chemother. | pmid:10770760 |
| Frolov A et al. | High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach. | 2000 | J. Biol. Chem. | pmid:10777574 |
| Habtemariam S et al. | 17-Epiacnistin-A, a further withanolide from the leaves of Discopodium penninervium. | 2000 | J. Nat. Prod. | pmid:10785427 |
| Wu SH et al. | Two novel secoergosterols from the fungus Tylopilus plumbeoviolaceus. | 2000 | J. Nat. Prod. | pmid:10785434 |