Campestanol

Campestanol is a lipid of Sterol Lipids (ST) class. The involved functions are known as Oxidation. The related lipids are campestanol, Sterols, campesterol and 6-oxocampestanol.

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Introduction

To understand associated biological information of Campestanol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Campestanol?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Campestanol

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Campestanol through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Campestanol?

There are no associated biomedical information in the current reference collection.

What functions are associated with Campestanol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Campestanol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Campestanol?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Campestanol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Campestanol

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Authors Title Published Journal PubMed Link
pmid:
Xu G et al. Campestanol (24-methyl-5alpha-cholestan-3beta-ol) absorption and distribution in New Zealand White rabbits: effect of dietary sitostanol. 1999 Metab. Clin. Exp. pmid:10094114
Gylling H and Miettinen TA Cholesterol reduction by different plant stanol mixtures and with variable fat intake. 1999 Metab. Clin. Exp. pmid:10337856
Noguchi T et al. Arabidopsis det2 is defective in the conversion of (24R)-24-methylcholest-4-En-3-one to (24R)-24-methyl-5alpha-cholestan-3-one in brassinosteroid biosynthesis. 1999 Plant Physiol. pmid:10398719
Plat J and Mensink RP Vegetable oil based versus wood based stanol ester mixtures: effects on serum lipids and hemostatic factors in non-hypercholesterolemic subjects. 2000 Atherosclerosis pmid:10580176
Nguyen TT et al. Cholesterol-lowering effect of stanol ester in a US population of mildly hypercholesterolemic men and women: a randomized controlled trial. 1999 Mayo Clin. Proc. pmid:10593347
Hallikainen MA et al. Plant stanol esters affect serum cholesterol concentrations of hypercholesterolemic men and women in a dose-dependent manner. 2000 J. Nutr. pmid:10736328
Sanders DJ et al. The safety evaluation of phytosterol esters. Part 6. The comparative absorption and tissue distribution of phytosterols in the rat. 2000 Food Chem. Toxicol. pmid:10828500
Seto H et al. Synthesis of 6-oxy functionalized campest-4-en-3-ones: efficient hydroperoxidation at C-6 of campest-5-en-3-one with molecular oxygen and silica gel. 2000 Steroids pmid:10936615
Noguchi T et al. Biosynthetic pathways of brassinolide in Arabidopsis. 2000 Plant Physiol. pmid:10982435
Plat J et al. Effects on serum lipids, lipoproteins and fat soluble antioxidant concentrations of consumption frequency of margarines and shortenings enriched with plant stanol esters. 2000 Eur J Clin Nutr pmid:11002377
Salen G et al. Hyperabsorption and retention of campestanol in a sitosterolemic homozygote: comparison with her mother and three control subjects. 2000 J. Lipid Res. pmid:11060358
Wasan KM et al. Assessing plasma pharmacokinetics of cholesterol following oral coadministration with a novel vegetable stanol mixture to fasting rats. 2001 J Pharm Sci pmid:11064375
Asami T et al. Selective interaction of triazole derivatives with DWF4, a cytochrome P450 monooxygenase of the brassinosteroid biosynthetic pathway, correlates with brassinosteroid deficiency in planta. 2001 J. Biol. Chem. pmid:11319239
Plat J and Mensink RP Effects of diets enriched with two different plant stanol ester mixtures on plasma ubiquinol-10 and fat-soluble antioxidant concentrations. 2001 Metab. Clin. Exp. pmid:11319712
Nomura T et al. Accumulation of 6-deoxocathasterone and 6-deoxocastasterone in Arabidopsis, pea and tomato is suggestive of common rate-limiting steps in brassinosteroid biosynthesis. 2001 Phytochemistry pmid:11382232
Volger OL et al. Dietary plant stanol esters reduce VLDL cholesterol secretion and bile saturation in apolipoprotein E*3-Leiden transgenic mice. 2001 Arterioscler. Thromb. Vasc. Biol. pmid:11397718
Volger OL et al. Dietary vegetable oil and wood derived plant stanol esters reduce atherosclerotic lesion size and severity in apoE*3-Leiden transgenic mice. 2001 Atherosclerosis pmid:11472737
Xu G et al. Plant stanol fatty acid esters inhibit cholesterol absorption and hepatic hydroxymethyl glutaryl coenzyme A reductase activity to reduce plasma levels in rabbits. 2001 Metab. Clin. Exp. pmid:11555847
Mensink RP et al. Effects of plant stanol esters supplied in low-fat yoghurt on serum lipids and lipoproteins, non-cholesterol sterols and fat soluble antioxidant concentrations. 2002 Atherosclerosis pmid:11755939
Ostlund RE et al. Gastrointestinal absorption and plasma kinetics of soy Delta(5)-phytosterols and phytostanols in humans. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:11882512
Nakajima N et al. Biosynthesis of cholestanol in higher plants. 2002 Phytochemistry pmid:12031446
Hallikainen M et al. Short-term LDL cholesterol-lowering efficacy of plant stanol esters. 2002 BMC Cardiovasc Disord pmid:12197945
De Graaf J et al. Consumption of tall oil-derived phytosterols in a chocolate matrix significantly decreases plasma total and low-density lipoprotein-cholesterol levels. 2002 Br. J. Nutr. pmid:12425728
Igel M et al. Comparison of the intestinal uptake of cholesterol, plant sterols, and stanols in mice. 2003 J. Lipid Res. pmid:12562824
pmid:12679174
Mezine I et al. Analysis of plant sterol and stanol esters in cholesterol-lowering spreads and beverages using high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectroscopy. 2003 J. Agric. Food Chem. pmid:12952413
Fujioka S and Yokota T Biosynthesis and metabolism of brassinosteroids. 2003 Annu Rev Plant Biol pmid:14502988
Pritchard PH et al. Comparison of cholesterol-lowering efficacy and anti-atherogenic properties of hydrogenated versus non-hydrogenated (Phytrol) tall oil-derived phytosterols in apo E-deficient mice. 2003 Sep-Nov Cardiovasc Drugs Ther pmid:15107599
Nomura T et al. Brassinosteroid deficiency due to truncated steroid 5alpha-reductase causes dwarfism in the lk mutant of pea. 2004 Plant Physiol. pmid:15286289
Koponen PS et al. Postmetamorphic Xenopus laevis shows decreased plasma triiodothyronine concentrations and phosphorylase activity due to subacute phytosterol exposure. 2004 Chemosphere pmid:15519414
Kabouche A et al. Components and antibacterial activity of the roots of Salvia jaminiana. 2005 Fitoterapia pmid:15893885
pmid:15896368
Chen J et al. The missense mutation in Abcg5 gene in spontaneously hypertensive rats (SHR) segregates with phytosterolemia but not hypertension. 2005 BMC Genet. pmid:16026620
pmid:16302759
Fujita S et al. Arabidopsis CYP90B1 catalyses the early C-22 hydroxylation of C27, C28 and C29 sterols. 2006 Plant J. pmid:16460510
de Jong A et al. Plant sterol or stanol consumption does not affect erythrocyte osmotic fragility in patients on statin treatment. 2006 Eur J Clin Nutr pmid:16482072
Nissinen MJ et al. Effects of plant stanol esters supplied in a fat free milieu by pastilles on cholesterol metabolism in colectomized human subjects. 2006 Nutr Metab Cardiovasc Dis pmid:16935701
Ohnishi T et al. CYP724B2 and CYP90B3 function in the early C-22 hydroxylation steps of brassinosteroid biosynthetic pathway in tomato. 2006 Biosci. Biotechnol. Biochem. pmid:16960392
Fassbender K et al. Moderately elevated plant sterol levels are associated with reduced cardiovascular risk--the LASA study. 2008 Atherosclerosis pmid:17137582
Patch CS et al. Plant sterols as dietary adjuvants in the reduction of cardiovascular risk: theory and evidence. 2006 Vasc Health Risk Manag pmid:17319460
pmid:17440516
Han J et al. [Analysis of phytosterol contents in Chinese plant food and primary estimation of its intake of people]. 2007 Wei Sheng Yan Jiu pmid:17712945
Vissers MN et al. Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia. 2008 Eur. J. Clin. Pharmacol. pmid:18320185
Monu E et al. Phytosterol effects on milk and yogurt microflora. 2008 J. Food Sci. pmid:18387114
Jia X et al. Co-administration of berberine and plant stanols synergistically reduces plasma cholesterol in rats. 2008 Atherosclerosis pmid:18430428
Weingärtner O et al. Controversial role of plant sterol esters in the management of hypercholesterolaemia. 2009 Eur. Heart J. pmid:19158117
Lin Y et al. Triterpenic Acids Present in Hawthorn Lower Plasma Cholesterol by Inhibiting Intestinal ACAT Activity in Hamsters. 2011 Evid Based Complement Alternat Med pmid:19228775
pmid:19263798
Lin DS et al. The effects of sterol structure upon sterol esterification. 2010 Atherosclerosis pmid:19679306