Beta-sitosterol is a lipid of Sterol Lipids (ST) class. Beta-sitosterol is associated with abnormalities such as Obesity, Diabetes, Cholestasis, Systemic disease and Diabetes Mellitus. The involved functions are known as Increased Cholesterol Synthesis, Synthesis, cholesterol metabolism, GLUCOSE TOLERANCE and cholesterol absorption. Beta-sitosterol often locates in Blood, Back, Cell membrane, soluble fraction and Body tissue. The related lipids are Sterols, lathosterol, Total cholesterol, campesterol and Cholestanes.
To understand associated biological information of Beta-sitosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Beta-sitosterol is suspected in Obesity, Cholestasis, Diabetes, Systemic disease, Diabetes Mellitus, Diabetes Mellitus, Insulin-Dependent and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Beta-sitosterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Hyperandrogenism | D017588 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Swar G et al. | Activity based evaluation of a traditional Ayurvedic medicinal plant: Saraca asoca (Roxb.) de Wilde flowers as estrogenic agents using ovariectomized rat model. | 2017 | J Ethnopharmacol | pmid:27884717 |
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| Hamdan IJA et al. | Sterols in infant formulas: validation of a gas chromatographic method. | 2017 | Int J Food Sci Nutr | pmid:28276904 |
| Debele TA et al. | Synthesis and characterization of redox-sensitive heparin-β-sitosterol micelles: Their application as carriers for the pharmaceutical agent, doxorubicin, and investigation of their antimetastatic activities in vitro. | 2017 | Mater Sci Eng C Mater Biol Appl | pmid:28415422 |
| Mba Nguekeu YM et al. | A kaempferol triglycoside from Tephrosia preussii Taub. (Fabaceae). | 2017 | Nat. Prod. Res. | pmid:28403640 |
| George S et al. | Melicodenine I, a new quinolinone alkaloid from Melicope denhamii leaves. | 2017 | Nat. Prod. Res. | pmid:27817202 |
| Rached MB et al. | Pedologic Factors Affecting Virgin Olive Oil Quality of "Chemlali" Olive Trees (Olea europaea L.). | 2017 | J Oleo Sci | pmid:28701656 |
| Paniagua-Pérez R et al. | EVALUATION OF THE ANTI-INFLAMMATORY CAPACITY OF BETA-SITOSTEROL IN RODENT ASSAYS. | 2017 | Afr J Tradit Complement Altern Med | pmid:28480389 |
| Mofidi Tabatabaei S et al. | A nor-diterpene from Salvia sahendica leaves. | 2017 | Nat. Prod. Res. | pmid:28278660 |
| Sabir A et al. | Discrimination of red and white rice bran from Indonesia using HPLC fingerprint analysis combined with chemometrics. | 2017 | Food Chem | pmid:27979152 |
| Xiao H et al. | Biological evaluation of phytoconstituents from Polygonum hydropiper. | 2017 | Nat. Prod. Res. | pmid:28000515 |
| Procházková T et al. | Phytoestrogens and sterols in waters with cyanobacterial blooms - Analytical methods and estrogenic potencies. | 2017 | Chemosphere | pmid:27974267 |
| Andrade I et al. | Cholesterol absorption and synthesis markers in Portuguese hypercholesterolemic adults: A cross-sectional study. | 2016 | Eur. J. Intern. Med. | pmid:26577223 |
| Maiyo F et al. | PHYTOCHEMISTRY, CYTOTOXICITY AND APOPTOSIS STUDIES OF B-SITOSTEROL-3-O-GLUCOSIDE AND Î’ -AMYRIN FROM PRUNUS AFRICANA. | 2016 | Afr J Tradit Complement Altern Med | pmid:28852726 |
| Contreras Cárdenas AV et al. | Antimicrobial, cytotoxic, and anti-inflammatory activities of Pleopeltis polylepis. | 2016 | J Ethnopharmacol | pmid:27794508 |
| Miras-Moreno B et al. | Bioactivity of Phytosterols and Their Production in Plant in Vitro Cultures. | 2016 | J. Agric. Food Chem. | pmid:27615454 |
| Rocha MJ et al. | Pollution by oestrogenic endocrine disruptors and β-sitosterol in a south-western European river (Mira, Portugal). | 2016 | Environ Monit Assess | pmid:27004433 |
| Ango PY et al. | Thonningiiflavanonol A and thonningiiflavanonol B, two novel flavonoids, and other constituents of Ficus thonningii Blume (Moraceae). | 2016 | Z. Naturforsch., C, J. Biosci. | pmid:26959540 |
| Zhao D et al. | Structural Features and Potent Antidepressant Effects of Total Sterols and β-sitosterol Extracted from Sargassum horneri. | 2016 | Mar Drugs | pmid:27367705 |
| Wrońska N et al. | The Role of fadD19 and echA19 in Sterol Side Chain Degradation by Mycobacterium smegmatis. | 2016 | Molecules | pmid:27164074 |
| Mishra RK et al. | Exploration of anti-Malassezia potential of Nyctanthes arbor-tristis L. and their application to combat the infection caused by Mala s1 a novel allergen. | 2016 | BMC Complement Altern Med | pmid:27036961 |
| Othman N et al. | Cyclopenta[b]benzofuran and Secodammarane Derivatives from the Stems of Aglaia stellatopilosa. | 2016 | J. Nat. Prod. | pmid:26974604 |
| Brzeska M et al. | Current Knowledge about Oxysterols: A Review. | 2016 | J. Food Sci. | pmid:27561087 |
| Wocheslander S et al. | Identification of Acyl Chain Oxidation Products upon Thermal Treatment of a Mixture of Phytosteryl/-stanyl Linoleates. | 2016 | J. Agric. Food Chem. | pmid:27933991 |
| Ras RT et al. | Increases in plasma plant sterols stabilize within four weeks of plant sterol intake and are independent of cholesterol metabolism. | 2016 | Nutr Metab Cardiovasc Dis | pmid:26806045 |
| Mendiara I et al. | Online solid-phase extraction-liquid chromatography-mass spectrometry to determine free sterols in human serum. | 2015 | Talanta | pmid:25476366 |
| Chaudhary S et al. | Evaluation of antioxidant and anticancer activity of extract and fractions of Nardostachys jatamansi DC in breast carcinoma. | 2015 | BMC Complement Altern Med | pmid:25886964 |
| Suttiarporn P et al. | Structures of phytosterols and triterpenoids with potential anti-cancer activity in bran of black non-glutinous rice. | 2015 | Nutrients | pmid:25756784 |
| Zanqui AB et al. | Subcritical extraction of flaxseed oil with n-propane: Composition and purity. | 2015 | Food Chem | pmid:26041217 |
| Mannock DA et al. | A comparative calorimetric and spectroscopic study of the effects of cholesterol and of the plant sterols β-sitosterol and stigmasterol on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine bilayer membranes. | 2015 | Biochim. Biophys. Acta | pmid:25911208 |
| Ras RT et al. | The effect of a low-fat spread with added plant sterols on vascular function markers: results of the Investigating Vascular Function Effects of Plant Sterols (INVEST) study. | 2015 | Am. J. Clin. Nutr. | pmid:25809853 |
| Semwal S et al. | Chemical constituents from rhizomes of Cautleya spicata (Sm.) Baker (Zingiberaceae). | 2015 | Nat. Prod. Res. | pmid:25751012 |
| Wang X et al. | Plasma cholesterol-lowering activity of dietary dihydrocholesterol in hypercholesterolemia hamsters. | 2015 | Atherosclerosis | pmid:26184696 |
| Aoki K et al. | Anagliptin decreases serum lathosterol level in patients with type 2 diabetes: a pilot study. | 2015 | Expert Opin Pharmacother | pmid:26098722 |
| Weingärtner O et al. | Vascular effects of oxysterols and oxyphytosterols in apoE -/- mice. | 2015 | Atherosclerosis | pmid:25765595 |
| Doukyu N and Nihei S | Cholesterol oxidase with high catalytic activity from Pseudomonas aeruginosa: Screening, molecular genetic analysis, expression and characterization. | 2015 | J. Biosci. Bioeng. | pmid:25573142 |
| Rameshkumar KB et al. | Curcuma ecalcarata - new natural source of pinocembrin and piperitenone. | 2015 | Nat. Prod. Res. | pmid:25553726 |
| Li H et al. | β-sitosterol interacts with pneumolysin to prevent Streptococcus pneumoniae infection. | 2015 | Sci Rep | pmid:26631364 |
| Nakamoto M et al. | Diversification of sterol methyltransferase enzymes in plants and a role for β-sitosterol in oriented cell plate formation and polarized growth. | 2015 | Plant J. | pmid:26426526 |
| Mishra MK et al. | Characterization of Arabidopsis sterol glycosyltransferase TTG15/UGT80B1 role during freeze and heat stress. | 2015 | Plant Signal Behav | pmid:26382564 |
| Styrczewska M et al. | Flax Fiber Hydrophobic Extract Inhibits Human Skin Cells Inflammation and Causes Remodeling of Extracellular Matrix and Wound Closure Activation. | 2015 | Biomed Res Int | pmid:26347154 |
| Bu C et al. | Transcriptome Analysis of the Carmine Spider Mite, Tetranychus cinnabarinus (Boisduval, 1867) (Acari: Tetranychidae), and Its Response to β-Sitosterol. | 2015 | Biomed Res Int | pmid:26078964 |
| Lomenick B et al. | Identification and characterization of β-sitosterol target proteins. | 2015 | Bioorg. Med. Chem. Lett. | pmid:25804720 |
| Ikeda I | Factors affecting intestinal absorption of cholesterol and plant sterols and stanols. | 2015 | J Oleo Sci | pmid:25742922 |
| Matsuoka K et al. | Competitive Solubilization of Cholesterol/Cholesteryl Oleate and Seven Species of Sterol/Stanol in Model Intestinal Solution System. | 2015 | J Oleo Sci | pmid:26136176 |
| Dey P et al. | Chemical characterization and assessment of antioxidant potentiality of Streptocaulon sylvestre Wight, an endangered plant of sub-Himalayan plains of West Bengal and Sikkim. | 2015 | BMC Complement Altern Med | pmid:25888746 |
| Rosqvist F et al. | Potential role of milk fat globule membrane in modulating plasma lipoproteins, gene expression, and cholesterol metabolism in humans: a randomized study. | 2015 | Am. J. Clin. Nutr. | pmid:26016870 |
| Cole C et al. | Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice. | 2015 | BMC Complement Altern Med | pmid:26243305 |