Beta-sitosterol is a lipid of Sterol Lipids (ST) class. Beta-sitosterol is associated with abnormalities such as Obesity, Diabetes, Cholestasis, Systemic disease and Diabetes Mellitus. The involved functions are known as Increased Cholesterol Synthesis, Synthesis, cholesterol metabolism, GLUCOSE TOLERANCE and cholesterol absorption. Beta-sitosterol often locates in Blood, Back, Cell membrane, soluble fraction and Body tissue. The related lipids are Sterols, lathosterol, Total cholesterol, campesterol and Cholestanes.
To understand associated biological information of Beta-sitosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Beta-sitosterol is suspected in Obesity, Cholestasis, Diabetes, Systemic disease, Diabetes Mellitus, Diabetes Mellitus, Insulin-Dependent and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Beta-sitosterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Hyperandrogenism | D017588 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Goepel M et al. | Saw palmetto extracts potently and noncompetitively inhibit human alpha1-adrenoceptors in vitro. | 1999 | Prostate | pmid:10068345 |
| Baker VA et al. | Safety evaluation of phytosterol esters. Part 1. Assessment of oestrogenicity using a combination of in vivo and in vitro assays. | 1999 | Food Chem. Toxicol. | pmid:10069478 |
| Wilt TJ et al. | beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. | 1999 | BJU Int. | pmid:10368239 |
| Bouic PJ et al. | The effects of B-sitosterol (BSS) and B-sitosterol glucoside (BSSG) mixture on selected immune parameters of marathon runners: inhibition of post marathon immune suppression and inflammation. | 1999 | Int J Sports Med | pmid:10376483 |
| Bouic PJ and Lamprecht JH | Plant sterols and sterolins: a review of their immune-modulating properties. | 1999 | Altern Med Rev | pmid:10383481 |
| Goese M et al. | Biosynthesis of bitter acids in hops. A (13)C-NMR and (2)H-NMR study on the building blocks of humulone. | 1999 | Eur. J. Biochem. | pmid:10406953 |
| Mora MP et al. | Optimisation of plant sterols incorporation in human keratinocyte plasma membrane and modulation of membrane fluidity. | 1999 | Chem. Phys. Lipids | pmid:10533266 |
| Bortolomeazzi R et al. | Mass spectrometry characterization of the 5alpha-, 7alpha-, and 7beta-hydroxy derivatives of beta-sitosterol, campesterol, stigmasterol, and brassicasterol. | 1999 | J. Agric. Food Chem. | pmid:10552610 |
| Mensenkamp AR et al. | Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver. | 1999 | J. Biol. Chem. | pmid:10585451 |