lauric acid

lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.

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Introduction

To understand associated biological information of lauric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with lauric acid?

lauric acid is suspected in Renal tubular disorder, Hypertensive disease, Infection, Renal vascular disorder, Obesity, Mycoses and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with lauric acid

MeSH term MeSH ID Detail
Peripheral Arterial Disease D058729 7 associated lipids
Vascular System Injuries D057772 2 associated lipids
Atherosclerosis D050197 85 associated lipids
Stroke D020521 32 associated lipids
Brain Infarction D020520 17 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Vasculitis D014657 14 associated lipids
Thrombosis D013927 49 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Starvation D013217 47 associated lipids
Per page 10 20 50 | Total 33

PubChem Associated disorders and diseases

What pathways are associated with lauric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with lauric acid?

Related references are published most in these journals:

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What functions are associated with lauric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with lauric acid?

Related references are published most in these journals:

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What genes are associated with lauric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with lauric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with lauric acid

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Authors Title Published Journal PubMed Link
Otten N et al. Experimental treatment of equine sarcoid using a xanthate compound and recombinant human tumour necrosis factor alpha. 1994 Zentralbl Veterinarmed A pmid:7653114
Mohan S and Raetz CR Endotoxin biosynthesis in Pseudomonas aeruginosa: enzymatic incorporation of laurate before 3-deoxy-D-manno-octulosonate. 1994 J. Bacteriol. pmid:7961456
Lee CK et al. Relationship between lipophilicity and skin permeability of various drugs from an ethanol/water/lauric acid system. 1994 Biol. Pharm. Bull. pmid:7874070
Komata Y et al. Effect of fatty acid on the accumulation of thiamine disulfide in rat skin. 1994 Biol. Pharm. Bull. pmid:7920438
Keegan FP and Blum JJ Incorporation of label from acetate and laurate into the mannan of Leishmania donovani via the glyoxylate cycle. 1993 Nov-Dec J. Eukaryot. Microbiol. pmid:7904877
Sawamura A et al. Catalytic properties of rabbit kidney fatty acid omega-hydroxylase cytochrome P-450ka2 (CYP4A7). 1993 Biochim. Biophys. Acta pmid:8504139
Mustad VA et al. Comparison of the effects of diets rich in stearic acid versus myristic acid and lauric acid on platelet fatty acids and excretion of thromboxane A2 and PGI2 metabolites in healthy young men. 1993 Metab. Clin. Exp. pmid:8487669
Yasuda H et al. An animal model of chronic ischemic neuropathy with proliferative changes of nerve microvessel wall. 1993 J. Neurol. Sci. pmid:8289080
Doktycz MJ et al. Studies of DNA dumbbells. IV. Preparation and melting of a DNA dumbbell with the 16 base-pair sequence 5'G-T-A-T-C-C-C-T-C-T-G-G-A-T-A-C3' linked on the ends by dodecyl chains. 1993 Biopolymers pmid:8268405
Imaoka S et al. Identification of CYP2C23 expressed in rat kidney as an arachidonic acid epoxygenase. 1993 J. Pharmacol. Exp. Ther. pmid:8246128
Carlson GP Formation of fatty acid propyl esters in liver, lung and pancreas of rats administered 1-propanol. 1993 Res. Commun. Chem. Pathol. Pharmacol. pmid:8210685
Tenma T et al. Development of new lipophilic derivatives of tetragastrin: physicochemical characteristics and intestinal absorption of acyl-tetragastrin derivatives in rats. 1993 Pharm. Res. pmid:8272412
Straub P et al. Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity. 1993 Arch. Biochem. Biophys. pmid:8215458
Miwa T et al. Modulation of morphine action by lauric acid. 1993 Biol. Pharm. Bull. pmid:8220329
Smith SW and Anderson BD Salt and mesophase formation in aqueous suspensions of lauric acid. 1993 Pharm. Res. pmid:8272419
Orlowski M et al. Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids. 1993 Biochemistry pmid:8431436
Goldberg ML and Enig MG Palmitic and lauric acids and serum cholesterol. 1993 Am. J. Clin. Nutr. pmid:8338054
Mustranta A et al. Applications of immobilized lipases to transesterification and esterification reactions in nonaqueous systems. 1993 Enzyme Microb. Technol. pmid:7763454
Vorum H et al. Fatty acid and drug binding to a low-affinity component of human serum albumin, purified by affinity chromatography. 1992 Int. J. Pept. Protein Res. pmid:1483836
Hornung B et al. Medium chain length fatty acids stimulate triacylglycerol synthesis in tissue culture cells. 1992 Biochem. Pharmacol. pmid:1739406
Voelker TA et al. Fatty acid biosynthesis redirected to medium chains in transgenic oilseed plants. 1992 Science pmid:1621095
van Wijk GM et al. Antiviral nucleoside diphosphate diglycerides: improved synthesis and facilitated purification. 1992 J. Lipid Res. pmid:1331283
Knickle LC et al. The suppression of hepatic cytochrome P4504A mRNA mediated by the interferon inducer polyinosinic acid.polycytidylic acid. 1992 Biochem. Pharmacol. pmid:1380810
Denke MA and Grundy SM Comparison of effects of lauric acid and palmitic acid on plasma lipids and lipoproteins. 1992 Am. J. Clin. Nutr. pmid:1415008
Sohlenius AK et al. The effects of perfluoro-octanoic acid on hepatic peroxisome proliferation and related parameters show no sex-related differences in mice. 1992 Biochem. J. pmid:1497616
Ng TK et al. Dietary palmitic and oleic acids exert similar effects on serum cholesterol and lipoprotein profiles in normocholesterolemic men and women. 1992 J Am Coll Nutr pmid:1506599
Himejima M and Kubo I Antimicrobial agents from Licaria puchuri-major and their synergistic effect with polygodial. 1992 J. Nat. Prod. pmid:1517735
Miko M and Devínsky F Biochemical basis of cytotoxic activity of some new N'-oxides of N',N'-dimethylaminoalkylamides of dodecanoic acid. 1992 Drug Metabol Drug Interact pmid:1424644
Lemaire P et al. Subterminal hydroxylation of lauric acid by microsomes from a marine fish. 1992 Lipids pmid:1522763
Jin SJ et al. Incomplete fatty acid oxidation. The production and epimerization of 3-hydroxy fatty acids. 1992 J. Biol. Chem. pmid:1730577
Salaün JP et al. Stereochemistry of oxidized fatty acids generated during catalytic oxygenation of lauric acid and unsaturated analogs by plant microsomes. 1992 FEBS Lett. pmid:1607005
Garfinkel M et al. Insulinotropic potency of lauric acid: a metabolic rationale for medium chain fatty acids (MCF) in TPN formulation. 1992 J. Surg. Res. pmid:1593871
Okita RT and Okita JR Characterization of a cytochrome P450 from di(2-ethylhexyl) phthalate-treated rats which hydroxylates fatty acids. 1992 Arch. Biochem. Biophys. pmid:1567203
Adachi H et al. Inhibitory effect of prostaglandin E1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: optimized topical formulation with beta-cyclodextrin derivative and penetration enhancer HPE-101. 1992 J. Pharm. Pharmacol. pmid:1361553
Komata Y et al. In vitro percutaneous absorption of thiamine disulfide from a mixture of propylene glycol and fatty acid. 1992 J Pharm Sci pmid:1403716
Lundgren B et al. Effects of dietary treatment with 11 dicarboxylic acids, diethylcarboxylic esters and fatty acids on peroxisomal fatty acid beta-oxidation, epoxide hydrolases and lauric acid omega-hydroxylation in mouse liver. 1992 Biochem. Pharmacol. pmid:1540233
Blum JJ Effects of osmotic pressure on the oxidative metabolism of Leishmania major promastigotes. 1991 May-Jun J. Protozool. pmid:1679134
Hvattum E et al. Microsomal oxidation of dodecylthioacetic acid (a 3-thia fatty acid) in rat liver. 1991 Mar 15-Apr 1 Biochem. Pharmacol. pmid:1672593
Salerno JW and Smith DE The use of sesame oil and other vegetable oils in the inhibition of human colon cancer growth in vitro. 1991 Jan-Feb Anticancer Res. pmid:2018355
Bergeron N et al. Interaction between dietary proteins and lipids in the regulation of serum and liver lipids in the rabbit. Effect of fish protein. 1991 Lipids pmid:1762524
Hare WR and Wahle KW The participation of soluble factors in the omega-oxidation of fatty acids in the liver of the sheep. 1991 Lipids pmid:2051891
Giera DD and van Lier RB A convenient method for the determination of hepatic lauric acid omega-oxidation based on solvent partition. 1991 Fundam Appl Toxicol pmid:2055365
Nordström T et al. Inhibition of CD3-induced Ca2+ signals in Jurkat T-cells by myristic acid. 1991 Cell Calcium pmid:1834341
Ogiso T et al. Enhancement effect of lauric acid on the rectal absorption of propranolol from suppository in rats. 1991 Chem. Pharm. Bull. pmid:1806286
Watanabe T et al. Co-suppression by nicardipine, a calcium antagonist, of induction of microsomal lauric acid hydroxylation with peroxisome proliferation in clofibrate-treated rat liver. 1991 Chem. Pharm. Bull. pmid:1914008
Hara H et al. Effect of (+/-)-2-(dimethylamino)-1-[[o-(m-methoxyphenethyl)phenoxy] methyl]ethyl hydrogen succinate on experimental models of peripheral obstructive disease. 1991 Arzneimittelforschung pmid:1930349
Swinney DC et al. A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase. 1991 Biochem. Pharmacol. pmid:1662512
Ogiso T et al. Enhancement by fatty acids of the rectal absorption of propranolol: in vitro evaluation in the rat. 1991 J. Pharmacobio-dyn. pmid:1802986
Yamada J et al. Assay of fatty acid omega-hydroxylation using high-performance liquid chromatography with fluorescence labeling reagent, 3-bromomethyl-7-methoxy-1,4-benzoxazin-2-one (BrMB). 1991 Anal. Biochem. pmid:1839651
Dirven HA et al. Determination of the cytochrome P-450 IV marker, omega-hydroxylauric acid, by high-performance liquid chromatography and fluorimetric detection. 1991 J. Chromatogr. pmid:1860919
Maurich V et al. p-nitrophenyllaurate: a substrate for the high-performance liquid chromatographic determination of lipase activity. 1991 J. Chromatogr. pmid:1939456
Yamazaki M et al. The effect of fatty acids on the rectal absorption of acyclovir in rats. 1990 J. Pharm. Pharmacol. pmid:1979629
Radom J et al. Influence of chain length of pyrene fatty acids on their uptake and metabolism by Epstein-Barr-virus-transformed lymphoid cell lines from a patient with multisystemic lipid storage myopathy and from control subjects. 1990 Biochem. J. pmid:2165389
Ogiso T and Shintani M Mechanism for the enhancement effect of fatty acids on the percutaneous absorption of propranolol. 1990 J Pharm Sci pmid:2079652
Bergman T and Postlind H Characterization of pig kidney microsomal cytochrome P-450 catalysing 25-hydroxylation of vitamin D3 and C27 steroids. 1990 Biochem. J. pmid:2169238
Sauer G et al. Systemic treatment of a human epidermoid non-small cell lung carcinoma xenograft with a xanthate compound causes extensive intratumoral necrosis. 1990 Cancer Lett. pmid:2170004
Pedersen AO et al. Thermodynamic parameters for binding of fatty acids to human serum albumin. 1990 Eur. J. Biochem. pmid:2373077
Mensink RP and Katan MB Effect of dietary trans fatty acids on high-density and low-density lipoprotein cholesterol levels in healthy subjects. 1990 N. Engl. J. Med. pmid:2374566
Hickey AJ et al. Effect of hydrophobic coating on the behavior of a hygroscopic aerosol powder in an environment of controlled temperature and relative humidity. 1990 J Pharm Sci pmid:2292762
Aoyama T et al. Clofibrate-inducible rat hepatic P450s IVA1 and IVA3 catalyze the omega- and (omega-1)-hydroxylation of fatty acids and the omega-hydroxylation of prostaglandins E1 and F2 alpha. 1990 J. Lipid Res. pmid:2280187
Boddupalli SS et al. Fatty acid monooxygenation by cytochrome P-450BM-3. 1990 J. Biol. Chem. pmid:2407733
Brozek KA and Raetz CR Biosynthesis of lipid A in Escherichia coli. Acyl carrier protein-dependent incorporation of laurate and myristate. 1990 J. Biol. Chem. pmid:2203778
Miranda CL et al. Regiospecificity in the hydroxylation of lauric acid by rainbow trout hepatic cytochrome P450 isozymes. 1990 Biochem. Biophys. Res. Commun. pmid:2403346
Nakamura J et al. Effect of straight chain fatty acids on seizures induced by picrotoxin and pentylenetetrazole in mice. 1990 J. Pharmacobio-dyn. pmid:2341972
Menke G et al. Kinetics of drug binding to human serum albumin: allosteric and competitive inhibition at the benzodiazepine binding site by free fatty acids of various chain lengths. 1989 Jan-Feb Naunyn Schmiedebergs Arch. Pharmacol. pmid:2471088
Wada M et al. Mechanism of biosynthesis of unsaturated fatty acids in Pseudomonas sp. strain E-3, a psychrotrophic bacterium. 1989 J. Bacteriol. pmid:2753856
Ryals PE et al. Lipid modification during cytodifferentiation of Tetrahymena vorax. Whole cell phospholipids and triacylglycerols of microstomal and macrostomal phenotypes. 1989 Biochim. Biophys. Acta pmid:2730920
Sharma RK et al. Role of hepatic and renal cytochrome P-450 IVA1 in the metabolism of lipid substrates. 1989 Biochem. Pharmacol. pmid:2554928
Makowska JM et al. Species differences in the hepatic response to a potent peroxisome proliferator. 1989 Biochem. Soc. Trans. pmid:2628085
Laignelet L et al. Induction and inhibition of rat liver cytochrome(s) P-450 by an imidazole fungicide (prochloraz). 1989 Toxicology pmid:2631296
Jarabak R and Westley J The sulfur-cyanolysis sites of serum albumin: metabolite competition studies. 1989 J. Biochem. Toxicol. pmid:2634097
Leon W et al. Fatty acid composition of amastigote and trypomastigote forms of Trypanosoma cruzi. 1989 Acta Trop. pmid:2565074
Woolfrey SG et al. The effect of Miglycol 812 oil on the oral absorption of propranolol in the rat. 1989 J. Pharm. Pharmacol. pmid:2571709
Miranda CL et al. Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout. 1989 Arch. Biochem. Biophys. pmid:2536262
Imai Y et al. Structure-function relationships of cytochrome P-450 laurate (omega-1)-hydroxylase. 1989 Drug Metab. Rev. pmid:2680391
Graham SA Cuphea: a new plant source of medium-chain fatty acids. 1989 Crit Rev Food Sci Nutr pmid:2653730
Mishima M et al. Promotion of nasal absorption of insulin by glycyrrhetinic acid derivatives. I. 1989 J. Pharmacobio-dyn. pmid:2656985
Morisaki H [Inhibition of neutrophil function by solvent of injectable sedatives--effects of propylene glycol, ethanol and benzyl alcohol]. 1989 Masui pmid:2614886
Kocarek TA and Feller DR Quantitative assessment of enzyme induction by peroxisome proliferators and application to determination of effects on triglyceride biosynthesis in primary cultures of rat hepatocytes. 1989 Biochem. Pharmacol. pmid:2597188
Fibach E et al. Analysis of cellular heterogeneity in the response of human leukemic cells to photosensitization induced by pyrene-containing fatty acid. 1989 Leuk. Res. pmid:2559259
Yokotani N et al. Two forms of omega-hydroxylase toward prostaglandin A and laurate. cDNA cloning and their expression. 1989 J. Biol. Chem. pmid:2600085
Khodari M et al. Applications in drug analysis of carbon paste electrodes modified by fatty acids. 1989 J Pharm Biomed Anal pmid:2490534
Imai Y and Nakamura M Point mutations at threonine-301 modify substrate specificity of rabbit liver microsomal cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase). 1989 Biochem. Biophys. Res. Commun. pmid:2493247
Borlakoglu JT et al. Evidence for the induction of cytochrome P-452 in rat liver by Aroclor 1254, a commercial mixture of polychlorinated biphenyls. 1989 FEBS Lett. pmid:2497034
Aarsaether N et al. Changes in peroxisomes and mitochondria in liver of ethionine exposed rats: a biochemical and morphological investigation. 1989 Carcinogenesis pmid:2498002
Thomas H et al. Effect of hypolipidemic compounds on lauric acid hydroxylation and phase II enzymes. 1989 Biochem. Pharmacol. pmid:2500933
Uno T and Imai Y Identification of regions functioning in substrate interaction of rabbit liver cytochrome P-450 (laurate (omega-1)-hydroxylase). 1989 J. Biochem. pmid:2691506
Boiteux-Antoine AF et al. Comparative induction of drug-metabolizing enzymes by hypolipidaemic compounds. 1989 Gen. Pharmacol. pmid:2502468
Tambo F et al. Auto-oxidation of Lingula unguis and Siphonosoma cumanense hemerythrins induced by some perturbants. 1989 Biochem. Int. pmid:2764951
Thomas OR and White GF Metabolic pathway for the biodegradation of sodium dodecyl sulfate by Pseudomonas sp. C12B. 1989 Biotechnol. Appl. Biochem. pmid:2503014
Sharma RK et al. Differential induction of peroxisomal and microsomal fatty-acid-oxidising enzymes by peroxisome proliferators in rat liver and kidney. Characterisation of a renal cytochrome P-450 and implications for peroxisome proliferation. 1989 Eur. J. Biochem. pmid:2776771
Green PG et al. Enhanced in vitro skin permeation of cationic drugs. 1989 Pharm. Res. pmid:2798314
Ohhira S and Matsui H [Determination of dibutyltin compounds in polyvinyl chloride resin by capillary gas chromatography]. 1989 Nihon Eiseigaku Zasshi pmid:2746975
Imaoka S et al. Omega- and (omega-1)-hydroxylation of lauric acid and arachidonic acid by rat renal cytochrome P-450. 1989 Biochem. Int. pmid:2504167
Wong KL et al. Dietary cis-fatty acids that increase protein F1 phosphorylation enhance spatial memory. 1989 Brain Res. pmid:2598047
Stucki JW et al. Acylation of proteins by myristic acid in isolated mitochondria. 1989 J. Biol. Chem. pmid:2703494
Bugaut M In vivo incorporation of lauric acid into rat adipose tissue triacylglycerols. 1989 Lipids pmid:2761351
Leakey JE et al. Effects of aging and caloric restriction on hepatic drug metabolizing enzymes in the Fischer 344 rat. I: The cytochrome P-450 dependent monooxygenase system. 1989 Mech. Ageing Dev. pmid:2661932
Sanglard D and Loper JC Characterization of the alkane-inducible cytochrome P450 (P450alk) gene from the yeast Candida tropicalis: identification of a new P450 gene family. 1989 Gene pmid:2663647
Frolov AF et al. Fatty acid composition of lipopolysaccharides of the strains of different species of Yersinia. 1989 J Hyg Epidemiol Microbiol Immunol pmid:2723424